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  2. Rare Disease Genes
  3. ALG10

ALG10 gene related symptoms and diseases

All the information presented here about the ALG10 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,NCBIGENE,HGNC, Mendelian Rare Disease Search Engine.

Table of contents:

Top 5 symptoms and clinical features associated to ALG10 gene

Symptoms // Phenotype % Cases
Seizures Very Common - Between 80% and 100% cases
Arrhythmia Very Common - Between 80% and 100% cases
Sudden cardiac death Very Common - Between 80% and 100% cases
Syncope Very Common - Between 80% and 100% cases
Cardiac arrest Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with ALG10 gene alterations may also develop some of the following symptoms and phenotypes:

  • Commonly - More than 50% cases

  • Ventricular tachycardia
  • Ventricular arrhythmia
  • Ventricular fibrillation
  • Prolonged QT interval
  • Epileptic spasms
  • Torsade de pointes
  • Abnormal T-wave
  • Atrial arrhythmia

And 1 more phenotypes, you can get all of them using our tools for rare diseases.

Rare diseases associated to ALG10 gene

Here you will find a list of rare diseases related to the ALG10. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


LONG QT SYNDROME 2; LQT2

Description

Congenital long QT syndrome is electrocardiographically characterized by a prolonged QT interval and polymorphic ventricular arrhythmias (torsade de pointes). These cardiac arrhythmias may result in recurrent syncope, seizure, or sudden death (Jongbloed et al., 1999).For a discussion of genetic heterogeneity of long QT syndrome, see LQT1 (OMIM ).

Most common symptoms of LONG QT SYNDROME 2; LQT2

  • Seizures
  • Arrhythmia
  • Sudden cardiac death
  • Syncope
  • Cardiac arrest


More info about LONG QT SYNDROME 2; LQT2

SOURCES: OMIM


Potential gene panels for ALG10 gene

Cardiac conduction changes (NGS panel for 27 genes) Panel

Portugal.

By CGC Genetics Cardiac conduction changes (NGS panel for 27 genes) that also includes the following genes: RYR2 SCN1B SCN4B SCN5A SNTA1 TRDN CACNA1C CACNB2 CALM1 CASQ2

More info about this panel
Portugal.

Long QT syndrome (NGS panel for 14 genes) Panel

Portugal.

By CGC Genetics Long QT syndrome (NGS panel for 14 genes) that also includes the following genes: SCN4B SCN5A SNTA1 CACNA1C CAV3 ALG10 AKAP9 ANK2 KCNE1 KCNE2

More info about this panel
Portugal.

Cardiomyopathy and changes in cardiac conduction (NGS panel for 59 genes) Panel

Portugal.

By CGC Genetics Cardiomyopathy and changes in cardiac conduction (NGS panel for 59 genes) that also includes the following genes: RYR2 SCN1B SCN4B SCN5A SGCD SNTA1 TCAP TNNC1 TNNI3 TNNT2

More info about this panel
Portugal.

ALG10 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the ALG10 gene.

More info about this panel
United States.

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