XRCC3 gene related symptoms and diseases
All the information presented here about the XRCC3 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,OMIM,NCBIGENE, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to XRCC3 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Neoplasm | Very Common - Between 80% and 100% cases |
| Pain | Uncommon - Between 30% and 50% cases |
| Carcinoma | Uncommon - Between 30% and 50% cases |
| Gynecomastia | Uncommon - Between 30% and 50% cases |
| Breast carcinoma | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with XRCC3 gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Sarcoma
- Ovarian neoplasm
- Prostate cancer
- Retinoblastoma
- Neoplasm of the breast
- Soft tissue sarcoma
- Endometrial carcinoma
- Melanoma
Rare diseases associated to XRCC3 gene
Here you will find a list of rare diseases related to the XRCC3. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
BREAST CANCER
Alternate names
BREAST CANCER Is also known as breast cancer, familial
Description
Breast cancer (referring to mammary carcinoma, not mammary sarcoma) is histopathologically and almost certainly etiologically and genetically heterogeneous. Important genetic factors have been indicated by familial occurrence and bilateral involvement.
Most common symptoms of BREAST CANCER
- Neoplasm
- Pain
- Carcinoma
- Gynecomastia
- Breast carcinoma
More info about BREAST CANCER
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 6; CMM6
Description
Malignant melanoma is a neoplasm of pigment-producing cells called melanocytes that occurs most often in the skin, but may also occur in the eyes, ears, gastrointestinal tract, leptomeninges, and oral and genital mucous membranes (summary by Habif, 2010).For a discussion of genetic heterogeneity of cutaneous malignant melanoma, see {155600}.
Most common symptoms of MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 6; CMM6
- Neoplasm
- Melanoma
More info about MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 6; CMM6
SOURCES: OMIM
Search interest in XRCC3
Potential gene panels for XRCC3 gene
Melanoma, cutaneous malignant, familial type 6, susceptibility to Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the XRCC3 gene.
More info about this panel Germany.
Breast cancer, susceptibility to Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the XRCC3 gene.
More info about this panel Germany.
Hereditary Cancer NGS Panel Panel
United States.
By Fulgent Genetics Fulgent Genetics Hereditary Cancer NGS Panel that also includes the following genes: ROBO2 BLM SDHA SDHB SDHC SDHD BMPR1A BRCA1 BRCA2 SMARCB1
More info about this panel United States.
XRCC3 Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the XRCC3 gene.
More info about this panel United States.
Comprehensive Cancer Panel Panel
United States.
By Fulgent Genetics Fulgent Genetics Comprehensive Cancer Panel that also includes the following genes: ROBO2 RUNX1 BLM SDHA SDHB SDHC SDHD BMPR1A BRCA1 BRCA2
More info about this panel United States.
Tempus xT assay Panel
United States.
By Tempus Labs, Inc. Tempus xT assay that also includes the following genes: BCL6 RIT1 BCL7A BCR ROS1 RPL5 RPS15 RPS6KB1 RUNX1 RXRA
More info about this panel United States.
CEN4GEN Comprehensive Hereditary Cancer Syndrome: Gene sequencing Panel Panel
Canada.
By CEN4GEN Institute for Genomics and Molecular Diagnostics CEN4GEN Comprehensive Hereditary Cancer Syndrome: Gene sequencing Panel that also includes the following genes: RNASEL RUNX1 BLM SDHA SDHB SDHC SDHD BMPR1A BRCA1 BRCA2
More info about this panel Canada.
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