WNK4 gene related symptoms and diseases
All the information presented here about the WNK4 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,ORPHANET,HGNC,OMIM, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to WNK4 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Hypertension | Very Common - Between 80% and 100% cases |
| Acidosis | Very Common - Between 80% and 100% cases |
| Hypoglycemia | Very Common - Between 80% and 100% cases |
| Hyperkalemia | Very Common - Between 80% and 100% cases |
| Renal tubular acidosis | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with WNK4 gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Pseudohypoaldosteronism
- Proximal renal tubular acidosis
- Hyperchloremic metabolic acidosis
- Hyperchloremia
Rare diseases associated to WNK4 gene
Here you will find a list of rare diseases related to the WNK4. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
PSEUDOHYPOALDOSTERONISM TYPE 2B
Alternate names
PSEUDOHYPOALDOSTERONISM TYPE 2B Is also known as pha2b
Most common symptoms of PSEUDOHYPOALDOSTERONISM TYPE 2B
- Hypertension
- Acidosis
- Hypoglycemia
- Hyperkalemia
- Renal tubular acidosis
More info about PSEUDOHYPOALDOSTERONISM TYPE 2B
Search interest in WNK4
Potential gene panels for WNK4 gene
ExomePLUS Electrolyte & Kidney Stone Panel
United States.
By Laboratory for Molecular Medicine Partners HealthCare Personalized Medicine ExomePLUS Electrolyte & Kidney Stone that also includes the following genes: SCNN1A SCNN1B SLC12A1 SLC12A3 SLC2A2 VDR WNK4 CASR BSND CDC73
More info about this panel United States.
WNK4. Sequencing of the exons 7 and 17 Panel
Spain.
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the WNK4 gene.
More info about this panel Spain.
WNK4. Complete sequencing Panel
Spain.
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the WNK4 gene.
More info about this panel Spain.
Pseudohypoaldosteronism type IIB (sequence analysis of WNK4 gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the WNK4 gene.
More info about this panel Portugal.
Pseudohypoaldosteronism (NGS panel of 9 genes) Panel
Portugal.
By CGC Genetics Pseudohypoaldosteronism (NGS panel of 9 genes) that also includes the following genes: SCNN1A SCNN1B SCNN1G WNK1 WNK4 CUL3 CYP11B2 KLHL3 NR3C2
More info about this panel Portugal.
Pseudohypoaldosteronism (NGS panel of 9 genes) Panel
Portugal.
By CGC Genetics Pseudohypoaldosteronism (NGS panel of 9 genes) that also includes the following genes: SCNN1A SCNN1B SCNN1G WNK1 WNK4 CUL3 CYP11B2 KLHL3 NR3C2
More info about this panel Portugal.
PSEUDOHYPOALDOSTERONISM, TYPE IIB Panel
Germany.
By Laboratory for Molecular Diagnostics Center for Nephrology and Metabolic Disorders
This panel specifically test the WNK4 gene.
More info about this panel Germany.
Wilms tumor, type 1 Panel
Germany.
By Laboratory for Molecular Diagnostics Center for Nephrology and Metabolic Disorders
This panel specifically test the WNK4 gene.
More info about this panel Germany.
Pseudohypoaldosteronism Type IIB Panel
United Kingdom.
By Exeter Molecular Genetics Laboratory
This panel specifically test the WNK4 gene.
More info about this panel United Kingdom.
Pseudohypoaldosteronism Type II Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Pseudohypoaldosteronism Type II Sequencing Panel with CNV Detection that also includes the following genes: WNK1 WNK4 CUL3 KLHL3
More info about this panel United States.
Pseudohypoaldosteronism Type II via WNK4 Gene Sequencing with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics
This panel specifically test the WNK4 gene.
More info about this panel United States.
Hypertension Panel
Germany.
By Institute of Human Genetics Uniklinik RWTH Aachen Hypertension that also includes the following genes: SCNN1A SCNN1G SDHA SDHB SDHC SDHD WNK1 WNK4 CUL3 CYP17A1
More info about this panel Germany.
Hereditary kidney disorders - different panels Panel
Germany.
By Institute of Human Genetics Uniklinik RWTH Aachen Hereditary kidney disorders - different panels that also includes the following genes: BCS1L ROBO2 CNNM2 CFB SALL1 ATXN10 SCNN1A SCNN1B SCNN1G SDCCAG8
More info about this panel Germany.
Nephrology Endocrinology and Electrolytes - panels Panel
Germany.
By MGZ Medical Genetics Center Nephrology Endocrinology and Electrolytes - panels that also includes the following genes: ROBO2 SALL1 BLK BMP4 BMP7 SIX1 SIX2 SIX5 SLC12A1 SLC12A3
More info about this panel Germany.
Bartter Syndrome panel Panel
Germany.
By Centogene AG - the Rare Disease Company Bartter Syndrome panel that also includes the following genes: SCNN1A SCNN1B SCNN1G SLC12A1 SLC12A2 SLC12A3 SLC12A7 SLC4A4 CA2 SLC12A5
More info about this panel Germany.
Pseudohypoaldosteronism, type IIB Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the WNK4 gene.
More info about this panel Germany.
Pseudohypoaldosteronism Panel Panel
Germany.
By CeGaT GmbH Pseudohypoaldosteronism Panel that also includes the following genes: SCNN1A SCNN1B SCNN1G WNK1 WNK4 CUL3 HSD11B2 KLHL3 NR3C2
More info about this panel Germany.
BARTTER SYNDROME Panel
Spain.
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases BARTTER SYNDROME that also includes the following genes: SCNN1A SCNN1B SCNN1G SLC12A1 SLC12A2 SLC12A3 SLC12A7 SLC4A4 CA2 SLC12A5
More info about this panel Spain.
Pseudohypoaldosteronism Type 2 NGS Panel Panel
United States.
By Fulgent Genetics Fulgent Genetics Pseudohypoaldosteronism Type 2 NGS Panel that also includes the following genes: WNK1 WNK4 CUL3 KLHL3
More info about this panel United States.
WNK4 Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the WNK4 gene.
More info about this panel United States.
KidneySeq - 264 Genes Panel
United States.
By Iowa Institute of Human Genetics University of Iowa KidneySeq - 264 Genes that also includes the following genes: ROBO2 CNNM2 SALL1 ATXN10 SCNN1A SCNN1B SCNN1G SDCCAG8 BMP4 SEMA3E
More info about this panel United States.
Pseudohypoaldosteronism Panel Panel
Finland.
By Blueprint Genetics Pseudohypoaldosteronism Panel that also includes the following genes: SCNN1A SCNN1B SCNN1G WNK1 WNK4 CUL3 HSD11B2 KCNJ5 KLHL3 NR3C2
More info about this panel Finland.
Pseudohypoaldosteronism Type II NGS and Deletion/Duplication Panel Panel
United States.
By DDC Clinic Molecular Diagnostics Laboratory DDC Clinic, Center for Special Needs Children Pseudohypoaldosteronism Type II NGS and Deletion/Duplication Panel that also includes the following genes: WNK1 WNK4 CUL3 KLHL3
More info about this panel United States.
WNK4 Gene Sequencing and Deletion/Duplication Analysis Panel
United States.
By DDC Clinic Molecular Diagnostics Laboratory DDC Clinic, Center for Special Needs Children
This panel specifically test the WNK4 gene.
More info about this panel United States.
PSEUDOHYPOALDOSTERONISM, TYPE 2 - GORDON SYNDROME (AUTOSOMAL DOMINANT) Panel
Spain.
By Laboratorio de Genetica Clinica SL PSEUDOHYPOALDOSTERONISM, TYPE 2 - GORDON SYNDROME (AUTOSOMAL DOMINANT) that also includes the following genes: WNK1 WNK4 CUL3 KLHL3
More info about this panel Spain.
PSEUDOHYPOALDOSTERONISM NGS PANEL Panel
Spain.
By Laboratorio de Genetica Clinica SL PSEUDOHYPOALDOSTERONISM NGS PANEL that also includes the following genes: SCNN1A SCNN1B SCNN1G WNK1 WNK4 CUL3 HSD11B2 KLHL3 NR3C2
More info about this panel Spain.
BARTTER SYNDROME NGS PANEL Panel
Spain.
By Laboratorio de Genetica Clinica SL BARTTER SYNDROME NGS PANEL that also includes the following genes: SCNN1A SCNN1B SCNN1G SLC12A1 SLC12A2 SLC12A3 SLC12A7 SLC4A4 CA2 SLC12A5
More info about this panel Spain.
Pseudohypoaldosteronism Type IIB , Sequencing WNK4 Panel
Spain.
By Reference Laboratory Genetics
This panel specifically test the WNK4 gene.
More info about this panel Spain.
Bartter Syndrome and related disorders , Panel Massive Sequencing (NGS) 22 Genes Panel
Spain.
By Reference Laboratory Genetics Bartter Syndrome and related disorders , Panel Massive Sequencing (NGS) 22 Genes that also includes the following genes: SCNN1A SCNN1B SCNN1G SLC12A1 SLC12A3 CA2 WNK1 WNK4 CASR BSND
More info about this panel Spain.
Pseudohypoaldosteronism , Panel Massive Sequencing (NGS) 9 Genes Panel
Spain.
By Reference Laboratory Genetics Pseudohypoaldosteronism , Panel Massive Sequencing (NGS) 9 Genes that also includes the following genes: SCNN1A SCNN1B SCNN1G WNK1 WNK4 CUL3 HSD11B2 KLHL3 NR3C2
More info about this panel Spain.
Tempus xO assay Panel
United States.
By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2
More info about this panel United States.
Pseudohypoaldosteronism Type II: gene sequencing panel Panel
Canada.
By CEN4GEN Institute for Genomics and Molecular Diagnostics Pseudohypoaldosteronism Type II: gene sequencing panel that also includes the following genes: WNK1 WNK4 CUL3 KLHL3
More info about this panel Canada.
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