VEGFC gene related symptoms and diseases

All the information presented here about the VEGFC gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,NCBIGENE,OMIM,HGNC, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to VEGFC gene

Symptoms // Phenotype % Cases
Hyperkeratosis Uncommon - Between 30% and 50% cases
Lymphedema Uncommon - Between 30% and 50% cases
Cellulitis Uncommon - Between 30% and 50% cases
Hydrocele testis Uncommon - Between 30% and 50% cases
Prominent superficial veins Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with VEGFC gene alterations may also develop some of the following symptoms and phenotypes:
  • Not very common - Between 30% and 50% cases

  • Toenail dysplasia

Rare diseases associated to VEGFC gene

Here you will find a list of rare diseases related to the VEGFC. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


LYMPHEDEMA, HEREDITARY, ID; LMPH1D

Most common symptoms of LYMPHEDEMA, HEREDITARY, ID; LMPH1D

  • Hyperkeratosis
  • Lymphedema
  • Cellulitis
  • Hydrocele testis
  • Prominent superficial veins


More info about LYMPHEDEMA, HEREDITARY, ID; LMPH1D

SOURCES: OMIM

MILROY DISEASE

Alternate names

MILROY DISEASE Is also known as hereditary lymphedema type i, nonne-milroy lymphedema, congenital primary lymphedema

Description

Milroy disease is a frequent form of primary lymphedema (see this term) characterized generally by painless, chronic lower-limb lymphedema found at birth or developing in the early neonatal period.


More info about MILROY DISEASE

SOURCES: ORPHANET


Potential gene panels for VEGFC gene

NGS Vascular Disorders Panel Panel

United States.

By Greenwood Genetic Center Diagnostic Laboratories Greenwood Genetic Center NGS Vascular Disorders Panel that also includes the following genes: SOX18 TEK VEGFC GLMN KRIT1 STAMBP GJC2 ACVRL1 CCM2 CCBE1

More info about this panel
United States.

Lymphedema NGS Multi-Gene Panel (36 Genes) Panel

Netherlands.

By Laboratory of genome diagnostics Academic Medical Center, University of Amsterdam Lymphedema NGS Multi-Gene Panel (36 Genes) that also includes the following genes: BRAF SOS1 SOX18 VEGFC CBL SHOC2 GJC2 TUBGCP6 CDK19 SPRED1

More info about this panel
Netherlands.

Lymphedema hereditary, IA (sequence analysis of VEGFC gene) Panel

Portugal.

By CGC Genetics

This panel specifically test the VEGFC gene.

More info about this panel
Portugal.

Lymphedema Sequencing Panel with CNV Detection Panel

United States.

By PreventionGenetics PreventionGenetics Lymphedema Sequencing Panel with CNV Detection that also includes the following genes: SOX18 VEGFC GJC2 FAT4 PIEZO1 CCBE1 FLT4 FOXC2 GATA2 GJA1

More info about this panel
United States.

Vascular and lymphatic disorders Panel Panel

Germany.

By CeGaT GmbH Vascular and lymphatic disorders Panel that also includes the following genes: SOX18 TREX1 SERPING1 VEGFC KRIT1 GJC2 ACVRL1 CCM2 FAT4 CCBE1

More info about this panel
Germany.

Primary lymphedema and Hydrops fetalis Panel

Belgium.

By Center for Human Genetics Cliniques Universitaires Saint Luc Primary lymphedema and Hydrops fetalis that also includes the following genes: SOS1 SOX18 VEGFC GJC2 FAT4 PIEZO1 CCBE1 EPHB4 FLT4 FOXC2

More info about this panel
Belgium.

VEGFC Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the VEGFC gene.

More info about this panel
United States.

MILROY SYNDROME SANGER PANEL Panel

Spain.

By Laboratorio de Genetica Clinica SL MILROY SYNDROME SANGER PANEL that also includes the following genes: VEGFC GJC2 FLT4

More info about this panel
Spain.

Lymphedema-Lethal Restrictive Dermopathy , Panel Massive Sequencing (NGS) 7 Genes Panel

Spain.

By Reference Laboratory Genetics Lymphedema-Lethal Restrictive Dermopathy , Panel Massive Sequencing (NGS) 7 Genes that also includes the following genes: SOX18 VEGFC ZMPSTE24 FLT4 FOXC2 GATA2 KIF11

More info about this panel
Spain.

Tempus xO assay Panel

United States.

By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2

More info about this panel
United States.

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