TRPC6 gene related symptoms and diseases

All the information presented here about the TRPC6 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,OMIM,NCBIGENE,ORPHANET, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to TRPC6 gene

Symptoms // Phenotype % Cases
Proteinuria Uncommon - Between 30% and 50% cases
Stage 5 chronic kidney disease Uncommon - Between 30% and 50% cases
Nephrotic syndrome Uncommon - Between 30% and 50% cases
Chronic kidney disease Uncommon - Between 30% and 50% cases
Glomerulosclerosis Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with TRPC6 gene alterations may also develop some of the following symptoms and phenotypes:
  • Not very common - Between 30% and 50% cases

  • Focal segmental glomerulosclerosis

Rare diseases associated to TRPC6 gene

Here you will find a list of rare diseases related to the TRPC6. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


FOCAL SEGMENTAL GLOMERULOSCLEROSIS 2; FSGS2

Alternate names

FOCAL SEGMENTAL GLOMERULOSCLEROSIS 2; FSGS2 Is also known as glomerulosclerosis, focal segmental, 2

Description

Focal segmental glomerulosclerosis (FSGS) is a pathologic entity associated clinically with proteinuria, the nephrotic syndrome (NPHS), and progressive loss of renal function. It is a common cause of end-stage renal disease (ESRD) (review by Meyrier, 2005).For a general phenotypic description and a discussion of genetic heterogeneity of focal segmental glomerulosclerosis and nephrotic syndrome (NPHS), see FSGS1 (OMIM ).

Most common symptoms of FOCAL SEGMENTAL GLOMERULOSCLEROSIS 2; FSGS2

  • Proteinuria
  • Stage 5 chronic kidney disease
  • Nephrotic syndrome
  • Chronic kidney disease
  • Glomerulosclerosis


More info about FOCAL SEGMENTAL GLOMERULOSCLEROSIS 2; FSGS2

SOURCES: MESH OMIM

FAMILIAL IDIOPATHIC STEROID-RESISTANT NEPHROTIC SYNDROME WITH FOCAL SEGMENTAL HYALINOSIS

Alternate names

FAMILIAL IDIOPATHIC STEROID-RESISTANT NEPHROTIC SYNDROME WITH FOCAL SEGMENTAL HYALINOSIS Is also known as familial idiopathic steroid-resistant nephrotic syndrome with focal segmental glomerulosclerosis


More info about FAMILIAL IDIOPATHIC STEROID-RESISTANT NEPHROTIC SYNDROME WITH FOCAL SEGMENTAL HYALINOSIS

SOURCES: ORPHANET


Potential gene panels for TRPC6 gene

TRPC6 DNA Sequencing Test Panel

United States.

By Athena Diagnostics Inc

This panel specifically test the TRPC6 gene.

More info about this panel
United States.

Inherited Focal and Segmental Glomerulosclerosis (FSGS) Evaluation Panel

United States.

By Athena Diagnostics Inc Inherited Focal and Segmental Glomerulosclerosis (FSGS) Evaluation that also includes the following genes: TRPC6 NPHS2 ACTN4 INF2

More info about this panel
United States.

Test for Focal Segmental Glomerulosclerosis 2 Panel

Netherlands.

By Genome Diagnostics Laboratory University Medical Center Utrecht

This panel specifically test the TRPC6 gene.

More info about this panel
Netherlands.

FSGS Panel Panel

Netherlands.

By Genome Diagnostics Laboratory University Medical Center Utrecht FSGS Panel that also includes the following genes: TRPC6 NPHS2 CD2AP ACTN4 NPHS1

More info about this panel
Netherlands.

Exome PLUS Proteinuria/FSGS & Hematuria Panel

United States.

By Laboratory for Molecular Medicine Partners HealthCare Personalized Medicine Exome PLUS Proteinuria/FSGS & Hematuria that also includes the following genes: CFB TRPC6 TSC1 TSC2 C1QA C1QC WT1 C3 NPHS2 ADAMTS13

More info about this panel
United States.

Familial idiopathic steroid-resistant nephrotic syndrome with focal segmental hyalinosis (sequence analysis of TRPC6) Panel

Portugal.

By CGC Genetics

This panel specifically test the TRPC6 gene.

More info about this panel
Portugal.

Focal glomerulonephrosis (NGS panel for 11 genes) Panel

Portugal.

By CGC Genetics Focal glomerulonephrosis (NGS panel for 11 genes) that also includes the following genes: TRPC6 WT1 NPHS2 ANLN CD2AP ACTN4 CRB2 INF2 MYO1E NPHS1

More info about this panel
Portugal.

Focal Segmental Glomerulosclerosis 2 Panel

Belgium.

By Centre de Genetique Humaine Institut de Pathologie et de Genetique

This panel specifically test the TRPC6 gene.

More info about this panel
Belgium.

Focal segmental glomerulosclerosis 2 Panel

Germany.

By Laboratory for Molecular Diagnostics Center for Nephrology and Metabolic Disorders

This panel specifically test the TRPC6 gene.

More info about this panel
Germany.

Nephrotic Syndrome (NS)/Focal Segmental Glomerulosclerosis (FSGS) Sequencing Panel with CNV Detection Panel

United States.

By PreventionGenetics PreventionGenetics Nephrotic Syndrome (NS)/Focal Segmental Glomerulosclerosis (FSGS) Sequencing Panel with CNV Detection that also includes the following genes: SGPL1 SMARCAL1 TRPC6 WT1 NPHS2 ANLN CD2AP TP53RK ACTN4 SCARB2

More info about this panel
United States.

Steroid-Resistant Nephrotic Syndrome (SRNS)/ Focal Segmental Glomerulosclerosis (FSGS) via TRPC6 Gene Sequencing with CNV Detection Panel

United States.

By PreventionGenetics PreventionGenetics

This panel specifically test the TRPC6 gene.

More info about this panel
United States.

Nephrotic syndrome and related disorders Comprehensive panel Panel

United States.

By Connective Tissue Gene Tests Nephrotic syndrome and related disorders Comprehensive panel that also includes the following genes: SGPL1 SMARCAL1 TRPC6 WT1 NPHS2 ANLN CD2AP ACTN4 SCARB2 PLCE1

More info about this panel
United States.

Nephrotic syndrome and related disorders NGS panel Panel

United States.

By Connective Tissue Gene Tests Nephrotic syndrome and related disorders NGS panel that also includes the following genes: SGPL1 SMARCAL1 TRPC6 WT1 NPHS2 ANLN CD2AP ACTN4 SCARB2 PLCE1

More info about this panel
United States.

Nephrotic syndrome and related disorders Deletion / Duplication panel Panel

United States.

By Connective Tissue Gene Tests Nephrotic syndrome and related disorders Deletion / Duplication panel that also includes the following genes: SGPL1 SMARCAL1 TRPC6 WT1 NPHS2 ANLN CD2AP ACTN4 SCARB2 PLCE1

More info about this panel
United States.

Focal segmental glomerulosclerosis 2 Panel

Germany.

By Institute of Human Genetics Uniklinik RWTH Aachen

This panel specifically test the TRPC6 gene.

More info about this panel
Germany.

Hereditary kidney disorders - different panels Panel

Germany.

By Institute of Human Genetics Uniklinik RWTH Aachen Hereditary kidney disorders - different panels that also includes the following genes: BCS1L ROBO2 CNNM2 CFB SALL1 ATXN10 SCNN1A SCNN1B SCNN1G SDCCAG8

More info about this panel
Germany.

Nephrology Endocrinology and Electrolytes - panels Panel

Germany.

By MGZ Medical Genetics Center Nephrology Endocrinology and Electrolytes - panels that also includes the following genes: ROBO2 SALL1 BLK BMP4 BMP7 SIX1 SIX2 SIX5 SLC12A1 SLC12A3

More info about this panel
Germany.

Focal Segmental Glomerulosclerosis 2 Panel

Germany.

By Bioscientia GmbH Center for Human Genetics

This panel specifically test the TRPC6 gene.

More info about this panel
Germany.

Focal segmental glomerulosclerosis type 2 Panel

Germany.

By Centogene AG - the Rare Disease Company

This panel specifically test the TRPC6 gene.

More info about this panel
Germany.

Focal Segmental Glomerulosclerosis Panel Panel

Germany.

By CeGaT GmbH Focal Segmental Glomerulosclerosis Panel that also includes the following genes: TRPC6 ANLN CD2AP ALDH1A2 ACTN4 CRB2 COQ6 INF2 ARHGAP24 WDR73

More info about this panel
Germany.

NEPHROTIC SYNDROME Panel

Spain.

By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases NEPHROTIC SYNDROME that also includes the following genes: STS TRPC6 WT1 NPHS2 CD2AP PLCE1 COQ6 INF2 ITGA3 LAMB2

More info about this panel
Spain.

Glomerulosclerosis, focal segmental Panel

Spain.

By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases Glomerulosclerosis, focal segmental that also includes the following genes: TRPC6 WT1 NPHS2 CD2AP ACTN4 PLCE1 INF2 MYO1E NPHS1 PAX2

More info about this panel
Spain.

TRPC6 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the TRPC6 gene.

More info about this panel
United States.

KidneySeq - 264 Genes Panel

United States.

By Iowa Institute of Human Genetics University of Iowa KidneySeq - 264 Genes that also includes the following genes: ROBO2 CNNM2 SALL1 ATXN10 SCNN1A SCNN1B SCNN1G SDCCAG8 BMP4 SEMA3E

More info about this panel
United States.

Nephrotic Syndrome Panel Panel

Finland.

By Blueprint Genetics Nephrotic Syndrome Panel that also includes the following genes: SGPL1 SMARCAL1 TRPC6 WT1 NPHS2 ANLN CD2AP ACTN4 SCARB2 PLCE1

More info about this panel
Finland.

Nephrotic Syndrome and Focal Segmental Glomerulosclerosis Gene Set Panel

United States.

By Genomics and Pathology Services Washington University in St. Louis Nephrotic Syndrome and Focal Segmental Glomerulosclerosis Gene Set that also includes the following genes: SMARCAL1 TRPC6 WT1 NPHS2 ANLN CD2AP ACTN4 SCARB2 PLCE1 CRB2

More info about this panel
United States.

SYNDROME WITH FOCAL SEGMENTAL GLOMERULOSCLEROSIS NGS PANEL Panel

Spain.

By Laboratorio de Genetica Clinica SL SYNDROME WITH FOCAL SEGMENTAL GLOMERULOSCLEROSIS NGS PANEL that also includes the following genes: SGPL1 TRPC6 WT1 NPHS2 ANLN CD2AP ACTN4 PLCE1 NUP205 CRB2

More info about this panel
Spain.

STEROID-RESISTANT NEPHROTIC SYNDROME WITH FOCAL SEGMENTAL GLOMERULOSCLEROSIS. Panel

Spain.

By Laboratorio de Genetica Clinica SL STEROID-RESISTANT NEPHROTIC SYNDROME WITH FOCAL SEGMENTAL GLOMERULOSCLEROSIS. that also includes the following genes: TRPC6 CD2AP ACTN4 INF2 ARHGAP24 MYO1E

More info about this panel
Spain.

Focal Segmental Glomerulosclerosis Type 2 , Sequencing TRPC6 Gene Panel

Spain.

By Reference Laboratory Genetics

This panel specifically test the TRPC6 gene.

More info about this panel
Spain.

Congenital Nephrotic Syndrome , Panel Massive Sequencing (NGS) 13 Genes Panel

Spain.

By Reference Laboratory Genetics Congenital Nephrotic Syndrome , Panel Massive Sequencing (NGS) 13 Genes that also includes the following genes: TRPC6 WT1 NPHS2 CD2AP PLCE1 COQ6 INF2 ITGA3 LAMB2 ARHGDIA

More info about this panel
Spain.

Focal Segmental Glomerulosclerosis , Panel Massive Sequencing (NGS) 10 Genes Panel

Spain.

By Reference Laboratory Genetics Focal Segmental Glomerulosclerosis , Panel Massive Sequencing (NGS) 10 Genes that also includes the following genes: TRPC6 WT1 NPHS2 CD2AP ACTN4 PLCE1 INF2 MYO1E NPHS1 PAX2

More info about this panel
Spain.

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