TF gene related symptoms and diseases
All the information presented here about the TF gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,OMIM,HGNC,ORPHANET, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to TF gene
Symptoms // Phenotype | % Cases |
---|---|
Growth delay | Very Common - Between 80% and 100% cases |
Abnormality of the liver | Very Common - Between 80% and 100% cases |
Hypochromic anemia | Very Common - Between 80% and 100% cases |
Hypochromic microcytic anemia | Very Common - Between 80% and 100% cases |
Abnormality of the pancreas | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with TF gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Microcytic anemia
- Abnormality of the cardiovascular system
- Cirrhosis
- Scarring
- Pallor
- Anemia
- Arthritis
- Hypothyroidism
And 6 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to TF gene
Here you will find a list of rare diseases related to the TF. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
CONGENITAL ATRANSFERRINEMIA
Alternate names
CONGENITAL ATRANSFERRINEMIA Is also known as hypotransferrinemia, familial, congenital hypotransferrinemia
Description
Congenital atransferrinemia is a very rare hematologic disease caused by a transferrin (TF) deficiency and characterized by microcytic, hypochromic anemia (manifesting with pallor, fatigue and growth retardation) and iron overload, and that can be fatal if left untreated.
Most common symptoms of CONGENITAL ATRANSFERRINEMIA
- Growth delay
- Anemia
- Hepatomegaly
- Fatigue
- Congestive heart failure
Search interest in TF
Potential gene panels for TF gene
Hyperferritinemia Panel Panel
By Molecular Genetics Laboratory Centro de Investigaciones Endocrinologicas "Dr. Cesar Bergada" Hyperferritinemia Panel that also includes the following genes: SEC23B SLC40A1 TF TFR2 HAMP CDAN1 CP STEAP3 SLC25A38 ALAS2
More info about this panelATRANSFERRINEMIA Panel
By BLOODGENETICS BLOODGENETICS
This panel specifically test the TF gene.
More info about this panelNGS Panel for Iron related Anemias (including Aceruloplasminemia, Atransferrinemia, IRIDA, DMT1-deficiency =AHMIO1, Hypochromic microcytic anemia with iron overload 2=AHMIO2) Panel
By BLOODGENETICS BLOODGENETICS NGS Panel for Iron related Anemias (including Aceruloplasminemia, Atransferrinemia, IRIDA, DMT1-deficiency =AHMIO1, Hypochromic microcytic anemia with iron overload 2=AHMIO2) that also includes the following genes: SLC11A2 TF TMPRSS6 ACVR1 CP STEAP3 ATP4A ATP7B
More info about this panelTF Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the TF gene.
More info about this panelComprehensive Hematology Panel Panel
By Blueprint Genetics Comprehensive Hematology Panel that also includes the following genes: RHAG RIT1 RPL11 RPL15 RPL35A RPL5 RPS10 RPS19 RPS24 RPS26
More info about this panelAnemia Panel Panel
By Blueprint Genetics Anemia Panel that also includes the following genes: RHAG RPL11 RPL15 RPL35A RPL5 RPS10 RPS19 RPS24 RPS26 RPS29
More info about this panelAtransferrinemia , Sequencing TF Gene Panel
By Reference Laboratory Genetics
This panel specifically test the TF gene.
More info about this panelIf you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like CDKAL1 DBH CYP3A5 TBX4 OGDH DYNC1H1 IFNGR1