TEX11 gene related symptoms and diseases
All the information presented here about the TEX11 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,OMIM,NCBIGENE,HGNC, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to TEX11 gene
Symptoms // Phenotype | % Cases |
---|---|
Azoospermia | Very Common - Between 80% and 100% cases |
Abnormality of metabolism/homeostasis | Uncommon - Between 30% and 50% cases |
Infertility | Uncommon - Between 30% and 50% cases |
Male infertility | Uncommon - Between 30% and 50% cases |
Testicular atrophy | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with TEX11 gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Decreased testicular size
- Increased circulating gonadotropin level
- Abnormal spermatogenesis
- Obstructive azoospermia
- Non-obstructive azoospermia
Rare diseases associated to TEX11 gene
Here you will find a list of rare diseases related to the TEX11. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
SPERMATOGENIC FAILURE, X-LINKED, 2; SPGFX2
Alternate names
SPERMATOGENIC FAILURE, X-LINKED, 2; SPGFX2 Is also known as male infertility from defect in meiosis
Most common symptoms of SPERMATOGENIC FAILURE, X-LINKED, 2; SPGFX2
- Abnormality of metabolism/homeostasis
- Infertility
- Azoospermia
- Male infertility
- Testicular atrophy
More info about SPERMATOGENIC FAILURE, X-LINKED, 2; SPGFX2
SOURCES: OMIM
MALE INFERTILITY WITH AZOOSPERMIA OR OLIGOZOOSPERMIA DUE TO SINGLE GENE MUTATION
Description
Male infertility with azoospermia or oligospermia due to single gene mutation is a rare, genetic male infertility due to sperm disorder characterized by the absence of a measurable amount of spermatozoa in the ejaculate (azoospermia), or a number of sperm in the ejaculate inferior to 15 million/mL (oligozoospermia), resulting from a mutation in a single gene known to cause azoo- or oligo-spermia. Sperm morphology may be normal.
Most common symptoms of MALE INFERTILITY WITH AZOOSPERMIA OR OLIGOZOOSPERMIA DUE TO SINGLE GENE MUTATION
- Decreased testicular size
- Azoospermia
- Increased circulating gonadotropin level
- Abnormal spermatogenesis
- Obstructive azoospermia
More info about MALE INFERTILITY WITH AZOOSPERMIA OR OLIGOZOOSPERMIA DUE TO SINGLE GENE MUTATION
SOURCES: ORPHANET
Search interest in TEX11
Potential gene panels for TEX11 gene
Male Infertility Sequencing Panel with CNV Detection Panel
By PreventionGenetics PreventionGenetics Male Infertility Sequencing Panel with CNV Detection that also includes the following genes: SEMA3A SEMA3E FOXL2 BRDT SOX10 SOX2 SOX3 SOX9 SRA1 SRD5A2
More info about this panelDisorders of Sex Development (DSD) and Infertility Sequencing Panel with CNV Detection Panel
By PreventionGenetics PreventionGenetics Disorders of Sex Development (DSD) and Infertility Sequencing Panel with CNV Detection that also includes the following genes: ROR2 SALL1 BMP15 BMP4 SEMA3A SEMA3E BMP7 FOXL2 BRDT SOS1
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