SYCE1 gene related symptoms and diseases
All the information presented here about the SYCE1 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,ORPHANET,NCBIGENE,OMIM, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to SYCE1 gene
Symptoms // Phenotype | % Cases |
---|---|
Azoospermia | Common - Between 50% and 80% cases |
Non-obstructive azoospermia | Common - Between 50% and 80% cases |
Increased circulating gonadotropin level | Common - Between 50% and 80% cases |
Aspiration | Uncommon - Between 30% and 50% cases |
Varicocele | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with SYCE1 gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Microphthalmia
- Amenorrhea
- Primary amenorrhea
- Macular dystrophy
- Decreased testicular size
- Abnormal spermatogenesis
- Obstructive azoospermia
Rare diseases associated to SYCE1 gene
Here you will find a list of rare diseases related to the SYCE1. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
SPERMATOGENIC FAILURE 15; SPGF15
Most common symptoms of SPERMATOGENIC FAILURE 15; SPGF15
- Aspiration
- Azoospermia
- Varicocele
- Non-obstructive azoospermia
More info about SPERMATOGENIC FAILURE 15; SPGF15
SOURCES: OMIM
PREMATURE OVARIAN FAILURE 12; POF12
Most common symptoms of PREMATURE OVARIAN FAILURE 12; POF12
- Microphthalmia
- Amenorrhea
- Primary amenorrhea
- Macular dystrophy
- Increased circulating gonadotropin level
More info about PREMATURE OVARIAN FAILURE 12; POF12
SOURCES: OMIM
MALE INFERTILITY WITH AZOOSPERMIA OR OLIGOZOOSPERMIA DUE TO SINGLE GENE MUTATION
Description
Male infertility with azoospermia or oligospermia due to single gene mutation is a rare, genetic male infertility due to sperm disorder characterized by the absence of a measurable amount of spermatozoa in the ejaculate (azoospermia), or a number of sperm in the ejaculate inferior to 15 million/mL (oligozoospermia), resulting from a mutation in a single gene known to cause azoo- or oligo-spermia. Sperm morphology may be normal.
Most common symptoms of MALE INFERTILITY WITH AZOOSPERMIA OR OLIGOZOOSPERMIA DUE TO SINGLE GENE MUTATION
- Decreased testicular size
- Azoospermia
- Increased circulating gonadotropin level
- Abnormal spermatogenesis
- Obstructive azoospermia
More info about MALE INFERTILITY WITH AZOOSPERMIA OR OLIGOZOOSPERMIA DUE TO SINGLE GENE MUTATION
SOURCES: ORPHANET
Search interest in SYCE1
Potential gene panels for SYCE1 gene
Female Infertility Sequencing Panel with CNV Detection Panel
By PreventionGenetics PreventionGenetics Female Infertility Sequencing Panel with CNV Detection that also includes the following genes: BMP15 SEMA3A SEMA3E FOXL2 SOX10 SOX2 SOX3 SOX9 SRA1 SRD5A2
More info about this panelMale Infertility Sequencing Panel with CNV Detection Panel
By PreventionGenetics PreventionGenetics Male Infertility Sequencing Panel with CNV Detection that also includes the following genes: SEMA3A SEMA3E FOXL2 BRDT SOX10 SOX2 SOX3 SOX9 SRA1 SRD5A2
More info about this panelDisorders of Sex Development (DSD) and Infertility Sequencing Panel with CNV Detection Panel
By PreventionGenetics PreventionGenetics Disorders of Sex Development (DSD) and Infertility Sequencing Panel with CNV Detection that also includes the following genes: ROR2 SALL1 BMP15 BMP4 SEMA3A SEMA3E BMP7 FOXL2 BRDT SOS1
More info about this panelSYCE1 Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the SYCE1 gene.
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