SUN5 gene related symptoms and diseases
All the information presented here about the SUN5 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,NCBIGENE,OMIM, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to SUN5 gene
Symptoms // Phenotype | % Cases |
---|---|
Infertility | Very Common - Between 80% and 100% cases |
Male infertility | Very Common - Between 80% and 100% cases |
Abnormality of the head | Very Common - Between 80% and 100% cases |
Reduced sperm motility | Very Common - Between 80% and 100% cases |
Abnormal sperm morphology | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with SUN5 gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Acephalic spermatozoa
Rare diseases associated to SUN5 gene
Here you will find a list of rare diseases related to the SUN5. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
SPERMATOGENIC FAILURE 16; SPGF16
Alternate names
SPERMATOGENIC FAILURE 16; SPGF16 Is also known as acephalic spermatozoa syndrome
Description
Spermatogenic failure-16 is characterized by acephalic spermatozoa causing male infertility. Semen from affected men consistently shows nearly 100% abnormally shaped spermatozoa, mostly made up of headless tails, with a small proportion of intact spermatozoa with an abnormal head-tail junction, as well as a few tailless heads. Ultrastructurally, the anomaly involves absence of the implantation fossa and basal plate between the sperm head and the tail (summary by Zhu et al., 2016).For a discussion of genetic heterogeneity of spermatogenic failure, see SPGF1 (OMIM ).
Most common symptoms of SPERMATOGENIC FAILURE 16; SPGF16
- Infertility
- Male infertility
- Abnormality of the head
- Reduced sperm motility
- Abnormal sperm morphology
More info about SPERMATOGENIC FAILURE 16; SPGF16
SOURCES: OMIM
Search interest in SUN5
Potential gene panels for SUN5 gene
Male Infertility Sequencing Panel with CNV Detection Panel
By PreventionGenetics PreventionGenetics Male Infertility Sequencing Panel with CNV Detection that also includes the following genes: SEMA3A SEMA3E FOXL2 BRDT SOX10 SOX2 SOX3 SOX9 SRA1 SRD5A2
More info about this panelDisorders of Sex Development (DSD) and Infertility Sequencing Panel with CNV Detection Panel
By PreventionGenetics PreventionGenetics Disorders of Sex Development (DSD) and Infertility Sequencing Panel with CNV Detection that also includes the following genes: ROR2 SALL1 BMP15 BMP4 SEMA3A SEMA3E BMP7 FOXL2 BRDT SOS1
More info about this panelSUN5 Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the SUN5 gene.
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