SUN5 gene related symptoms and diseases

All the information presented here about the SUN5 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,NCBIGENE,OMIM, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to SUN5 gene

Symptoms // Phenotype % Cases
Infertility Very Common - Between 80% and 100% cases
Male infertility Very Common - Between 80% and 100% cases
Abnormality of the head Very Common - Between 80% and 100% cases
Reduced sperm motility Very Common - Between 80% and 100% cases
Abnormal sperm morphology Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with SUN5 gene alterations may also develop some of the following symptoms and phenotypes:
  • Commonly - More than 50% cases

  • Acephalic spermatozoa

Rare diseases associated to SUN5 gene

Here you will find a list of rare diseases related to the SUN5. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


SPERMATOGENIC FAILURE 16; SPGF16

Alternate names

SPERMATOGENIC FAILURE 16; SPGF16 Is also known as acephalic spermatozoa syndrome

Description

Spermatogenic failure-16 is characterized by acephalic spermatozoa causing male infertility. Semen from affected men consistently shows nearly 100% abnormally shaped spermatozoa, mostly made up of headless tails, with a small proportion of intact spermatozoa with an abnormal head-tail junction, as well as a few tailless heads. Ultrastructurally, the anomaly involves absence of the implantation fossa and basal plate between the sperm head and the tail (summary by Zhu et al., 2016).For a discussion of genetic heterogeneity of spermatogenic failure, see SPGF1 (OMIM ).

Most common symptoms of SPERMATOGENIC FAILURE 16; SPGF16

  • Infertility
  • Male infertility
  • Abnormality of the head
  • Reduced sperm motility
  • Abnormal sperm morphology


More info about SPERMATOGENIC FAILURE 16; SPGF16

SOURCES: OMIM


Potential gene panels for SUN5 gene

Male Infertility Sequencing Panel with CNV Detection Panel

United States.

By PreventionGenetics PreventionGenetics Male Infertility Sequencing Panel with CNV Detection that also includes the following genes: SEMA3A SEMA3E FOXL2 BRDT SOX10 SOX2 SOX3 SOX9 SRA1 SRD5A2

More info about this panel
United States.

Disorders of Sex Development (DSD) and Infertility Sequencing Panel with CNV Detection Panel

United States.

By PreventionGenetics PreventionGenetics Disorders of Sex Development (DSD) and Infertility Sequencing Panel with CNV Detection that also includes the following genes: ROR2 SALL1 BMP15 BMP4 SEMA3A SEMA3E BMP7 FOXL2 BRDT SOS1

More info about this panel
United States.

SUN5 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the SUN5 gene.

More info about this panel
United States.

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