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SLC11A1 gene related symptoms and diseases

All the information presented here about the SLC11A1 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,HGNC,OMIM,NCBIGENE, Mendelian Rare Disease Search Engine.

Table of contents:

Top 5 symptoms and clinical features associated to SLC11A1 gene

Symptoms // Phenotype % Cases
Fever Common - Between 50% and 80% cases
Fatigue Common - Between 50% and 80% cases
Weight loss Common - Between 50% and 80% cases
Cough Common - Between 50% and 80% cases
Pain Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with SLC11A1 gene alterations may also develop some of the following symptoms and phenotypes:

  • Not very common - Between 30% and 50% cases

  • Immunodeficiency
  • Chest pain
  • Hemoptysis
  • Night sweats
  • Edema
  • Abnormal lung morphology

Rare diseases associated to SLC11A1 gene

Here you will find a list of rare diseases related to the SLC11A1. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO

Description

Mycobacterium tuberculosis latently infects approximately one-third of humanity and is comparable only to human immunodeficiency virus (HIV; see {609423}) as a leading infectious cause of mortality worldwide. Obstacles for controlling TB infection include lengthy treatment regimens of 6 to 9 months, drug resistance, lack of a highly efficacious vaccine, and incomplete understanding of the factors that control infectivity and disease progression. Although only 10% of individuals infected with M. tuberculosis develop active disease, the immune responses associated with TB susceptibility or resistance are not known. In addition, it is not known why some individuals have disseminated TB that spreads to the meninges and central nervous system, while most people have localized disease in the lungs. A number of studies suggest that host genetic factors influence susceptibility and resistance to TB (review by Berrington and Hawn, 2007).

Most common symptoms of MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO

  • Pain
  • Fever
  • Fatigue
  • Immunodeficiency
  • Weight loss


More info about MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO

SOURCES: OMIM MESH

BURULI ULCER, SUSCEPTIBILITY TO

Alternate names

BURULI ULCER, SUSCEPTIBILITY TO Is also known as mycobacterium ulcerans, susceptibility to

Description

Buruli ulcer is an infectious disease prevalent in many tropical and subtropical regions caused by infection with Mycobacterium ulcerans. It is the third most frequent mycobacterial disease in humans worldwide, after tuberculosis (OMIM ) and leprosy (OMIM ). Lesions are most common on exposed parts of the body, especially the limbs. Buruli ulcer derives its name from a county in Uganda, East Africa, north of Kampala, where the disease was found in the late 1950s in hundreds of people living near marshes and riverine areas near the Nile River (Clancey et al., 1961; Barker, 1971). The disease was first described in the medical literature in 1948 in a report on patients in Australia (MacCallum et al., 1948). Patients have also been reported from tropical areas in Latin America and Asia (Stienstra et al., 2006; van der Werf et al., 2005).

Most common symptoms of BURULI ULCER, SUSCEPTIBILITY TO

  • Edema


More info about BURULI ULCER, SUSCEPTIBILITY TO

SOURCES: OMIM

TUBERCULOSIS

Description

Tuberculosis (TB) is a contagious-infectious disease caused mainly by Mycobacterium tuberculosis that in most individuals is usually asymptomatic but that in at risk individuals (e.g. with diabetes or with HIV infection) can cause weakness, fever, weight loss, night sweat, and respiratory anomalies such as chronic cough, chest pain, hemoptysis or respiratory insufficiency.

Most common symptoms of TUBERCULOSIS

  • Fever
  • Fatigue
  • Weight loss
  • Cough
  • Abnormal lung morphology


More info about TUBERCULOSIS

SOURCES: ORPHANET


Potential gene panels for SLC11A1 gene

SLC11A1 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the SLC11A1 gene.

More info about this panel
United States.

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