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  2. Genes
  3. SERPIND1

SERPIND1 gene related symptoms and diseases

All the information presented here about the SERPIND1 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,OMIM,HGNC, Mendelian Rare Disease Search Engine.

Table of contents:

Top 5 symptoms and clinical features associated to SERPIND1 gene

Symptoms // Phenotype % Cases
Venous thrombosis Very Common - Between 80% and 100% cases
Thromboembolism Very Common - Between 80% and 100% cases
Pulmonary embolism Very Common - Between 80% and 100% cases
Deep venous thrombosis Very Common - Between 80% and 100% cases
Disseminated intravascular coagulation Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with SERPIND1 gene alterations may also develop some of the following symptoms and phenotypes:

  • Commonly - More than 50% cases

  • Recurrent deep vein thrombosis
  • Post-angioplasty coronary artery restenosis

Rare diseases associated to SERPIND1 gene

Here you will find a list of rare diseases related to the SERPIND1. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


HEPARIN COFACTOR II DEFICIENCY

Alternate names

HEPARIN COFACTOR II DEFICIENCY Is also known as thrombophilia due to heparin cofactor ii deficiency, thph10, hcf ii deficiency, hcf2 deficiency

Description

Heparin cofactor II (HCF2 ) rapidly inhibits thrombin in plasma in the presence of dermatan sulfate or heparin. Congenital HCF2 deficiency is associated with thromboembolism and is classified into type I (quantitative) or type II (qualitative) deficiency (Kondo et al., 1996).

Most common symptoms of HEPARIN COFACTOR II DEFICIENCY

  • Venous thrombosis
  • Thromboembolism
  • Pulmonary embolism
  • Deep venous thrombosis
  • Disseminated intravascular coagulation


More info about HEPARIN COFACTOR II DEFICIENCY

SOURCES: OMIM MESH


Potential gene panels for SERPIND1 gene

aCGH Deletion/Duplication Analysis Panel

United States.

By BloodCenter of Wisconsin Diagnostic Laboratories BloodCenter of Wisconsin, part of Versiti aCGH Deletion/Duplication Analysis that also includes the following genes: CFB RUNX1 STXBP2 TBXA2R THBD VWF WAS C3 C4BPA C4BPB

More info about this panel
United States.

SERPIND1 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the SERPIND1 gene.

More info about this panel
United States.

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