RAD54B gene related symptoms and diseases
All the information presented here about the RAD54B gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,HGNC,NCBIGENE, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to RAD54B gene
Symptoms // Phenotype | % Cases |
---|---|
Neoplasm | Very Common - Between 80% and 100% cases |
Hereditary nonpolyposis colorectal carcinoma | Uncommon - Between 30% and 50% cases |
T-cell lymphoma | Uncommon - Between 30% and 50% cases |
Chronic lymphatic leukemia | Uncommon - Between 30% and 50% cases |
B-cell lymphoma | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with RAD54B gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Hodgkin lymphoma
- Lymphoma
- Leukemia
- Uterine leiomyosarcoma
- Neoplasm of the stomach
- Transitional cell carcinoma of the bladder
- Carcinoma
- Colorectal polyposis
And 9 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to RAD54B gene
Here you will find a list of rare diseases related to the RAD54B. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
COLORECTAL CANCER; CRC
Alternate names
COLORECTAL CANCER; CRC Is also known as colon cancer
Description
Colorectal cancer is a heterogeneous disease that is common in both men and women. In addition to lifestyle and environmental risk factors, gene defects can contribute to an inherited predisposition to CRC. CRC is caused by changes in different molecular pathogenic pathways, such as chromosomal instability, CpG island methylator phenotype, and microsatellite instability. Chromosome instability is the most common alteration and is present in almost 85% of all cases (review by Schweiger et al., 2013).
Most common symptoms of COLORECTAL CANCER; CRC
- Neoplasm
- Carcinoma
- Oligodontia
- Colon cancer
- Colitis
More info about COLORECTAL CANCER; CRC
SOURCES: OMIM
NON-HODGKIN LYMPHOMA
Alternate names
NON-HODGKIN LYMPHOMA Is also known as nhl, non-hodgkin lymphoma
Description
Non-Hodgkin malignant lymphomas(NHL) is a heterogeneous group of malignant tumors of the lymphoid system.
Most common symptoms of NON-HODGKIN LYMPHOMA
- Neoplasm
- Leukemia
- Lymphoma
- Hodgkin lymphoma
- B-cell lymphoma
More info about NON-HODGKIN LYMPHOMA
Search interest in RAD54B
Potential gene panels for RAD54B gene
RAD54B Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the RAD54B gene.
More info about this panelSolid Tumor Gene Set Panel
By Genomics and Pathology Services Washington University in St. Louis Solid Tumor Gene Set that also includes the following genes: RIT1 ROS1 RXRA FOXL2 BRAF BRCA1 BRCA2 SMARCA4 SMARCB1 KDM5C
More info about this panelBreast Tumors Gene Set Panel
By Genomics and Pathology Services Washington University in St. Louis Breast Tumors Gene Set that also includes the following genes: RUNX1 BRAF BRCA1 BRCA2 STK11 TP53 FBXW7 RAD54B CDH1 CDK4
More info about this panelTempus xO assay Panel
By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2
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