PTPRJ gene related symptoms and diseases
All the information presented here about the PTPRJ gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,HGNC,OMIM, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to PTPRJ gene
Symptoms // Phenotype | % Cases |
---|---|
Neoplasm | Very Common - Between 80% and 100% cases |
Carcinoma | Very Common - Between 80% and 100% cases |
Oligodontia | Very Common - Between 80% and 100% cases |
Colon cancer | Very Common - Between 80% and 100% cases |
Colitis | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with PTPRJ gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Renal cell carcinoma
- Ulcerative colitis
- Retinoblastoma
- Leiomyosarcoma
- Endometrial carcinoma
- Colorectal polyposis
- Transitional cell carcinoma of the bladder
- Hereditary nonpolyposis colorectal carcinoma
And 2 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to PTPRJ gene
Here you will find a list of rare diseases related to the PTPRJ. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
COLORECTAL CANCER; CRC
Alternate names
COLORECTAL CANCER; CRC Is also known as colon cancer
Description
Colorectal cancer is a heterogeneous disease that is common in both men and women. In addition to lifestyle and environmental risk factors, gene defects can contribute to an inherited predisposition to CRC. CRC is caused by changes in different molecular pathogenic pathways, such as chromosomal instability, CpG island methylator phenotype, and microsatellite instability. Chromosome instability is the most common alteration and is present in almost 85% of all cases (review by Schweiger et al., 2013).
Most common symptoms of COLORECTAL CANCER; CRC
- Neoplasm
- Carcinoma
- Oligodontia
- Colon cancer
- Colitis
More info about COLORECTAL CANCER; CRC
SOURCES: OMIM
Search interest in PTPRJ
Potential gene panels for PTPRJ gene
PTPRJ Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the PTPRJ gene.
More info about this panelTempus xO assay Panel
By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2
More info about this panelIf you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like RNU4ATAC NCKAP5 RGR PCK2 VANGL1 CALM2 LAS1L