PRCC gene related symptoms and diseases
All the information presented here about the PRCC gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,OMIM,ORPHANET,HGNC, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to PRCC gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Neoplasm | Uncommon - Between 30% and 50% cases |
| Obesity | Uncommon - Between 30% and 50% cases |
| Carcinoma | Uncommon - Between 30% and 50% cases |
| Renal cell carcinoma | Uncommon - Between 30% and 50% cases |
| Renal neoplasm | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with PRCC gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Papillary renal cell carcinoma
- Clear cell renal cell carcinoma
Rare diseases associated to PRCC gene
Here you will find a list of rare diseases related to the PRCC. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
PAPILLARY RENAL CELL CARCINOMA
Alternate names
PAPILLARY RENAL CELL CARCINOMA Is also known as papillary renal cell adenocarcinoma
Description
Papillary renal cell carcinoma is a rare subtype of renal cell carcinoma, arising from the renal tubular epithelium and showing a papillary growth pattern, which typically manifests with hematuria, flank pain, palpable abdominal mass or nonspecific symptoms, such as fatigue, weight loss or fever. Symptoms related to metastatic spread, such as bone pain or persistent cough, are frequently associated since early diagnosis is not common. It is typically multifocal, bilateral, and in most cases sporadic, although different hereditary syndromes, such as Hereditary leiomyoma renal cell carcinoma, Birt-Hogg-Dubé syndrome and Tuberous sclerosis, may predispose to the development of papillary renal cell carcinoma.
Most common symptoms of PAPILLARY RENAL CELL CARCINOMA
- Neoplasm
- Obesity
- Carcinoma
- Renal cell carcinoma
- Renal neoplasm
More info about PAPILLARY RENAL CELL CARCINOMA
MIT FAMILY TRANSLOCATION RENAL CELL CARCINOMA
Alternate names
MIT FAMILY TRANSLOCATION RENAL CELL CARCINOMA Is also known as carcinoma associated with mitf/tfe translocation, translocation renal cell carcinoma
Description
MiT family translocation renal cell carcinoma (t-RCC) is a rare subtype of renal cell carcinoma with recurrent genetic abnormalities, harboring rearrangements of the TFE3 (Xp11 t-RCC) or TFEB [t(6;11) t-RCC] genes. The t(6;11) t-RCC has distinctive histologic features of biphasic appearance with larger epitheloid and smaller eosinophilic cells. The symptoms are usually non-specific and include hematuria, flank pain, palpable abdominal mass and/or systemic symptoms of anemia, fatigue and fever.
More info about MIT FAMILY TRANSLOCATION RENAL CELL CARCINOMA
SOURCES: ORPHANET
Search interest in PRCC
Potential gene panels for PRCC gene
PRCC Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the PRCC gene.
More info about this panel United States.
Caris MI TumorSeek 592-Gene NGS Panel Panel
United States.
By Caris Life Sciences Caris MI TumorSeek 592-Gene NGS Panel that also includes the following genes: BCL6 BCL7A BCL9 BCR ROS1 RPL10 RPL22 RPL5 RPN1 RUNX1
More info about this panel United States.
Tempus xT assay Panel
United States.
By Tempus Labs, Inc. Tempus xT assay that also includes the following genes: BCL6 RIT1 BCL7A BCR ROS1 RPL5 RPS15 RPS6KB1 RUNX1 RXRA
More info about this panel United States.
Tempus xO assay Panel
United States.
By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2
More info about this panel United States.
If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like ATM REN TPP2 PAH RFX6 LAS1L SCN10A