PLUT gene related symptoms and diseases

All the information presented here about the PLUT gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,HGNC, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to PLUT gene

Symptoms // Phenotype % Cases
Type II diabetes mellitus Very Common - Between 80% and 100% cases
Maturity-onset diabetes of the young Uncommon - Between 30% and 50% cases
Diabetes mellitus Uncommon - Between 30% and 50% cases
Insulin resistance Uncommon - Between 30% and 50% cases
Type I diabetes mellitus Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with PLUT gene alterations may also develop some of the following symptoms and phenotypes:
  • Not very common - Between 30% and 50% cases

  • Hyperinsulinemia
  • Hyperglycemia
  • Glucose intolerance
  • Fasting hyperinsulinemia
  • Decreased waist to hip ratio

Rare diseases associated to PLUT gene

Here you will find a list of rare diseases related to the PLUT. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 4; MODY4

Alternate names

MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 4; MODY4 Is also known as mody, type 4

Description

Monogenic diabetes caused by inactivating mutation(s) in the PDX1 gene, encoding pancreas/duodenum homeobox protein 1. Homozygous PDX1 mutations result in permanent neonatal diabetes.

Most common symptoms of MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 4; MODY4

  • Type II diabetes mellitus
  • Maturity-onset diabetes of the young


More info about MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 4; MODY4

SOURCES: MESH OMIM

DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM

Alternate names

DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM Is also known as noninsulin-dependent diabetes mellitus, maturity-onset diabetes, diabetes mellitus, type ii, t2d

Most common symptoms of DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM

  • Diabetes mellitus
  • Type II diabetes mellitus
  • Insulin resistance
  • Type I diabetes mellitus
  • Hyperinsulinemia


More info about DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM

SOURCES: OMIM ORPHANET



If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like NTF3 LGI4 CEP85L VWA3B KIT STAP1 TCN1