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  2. Rare Disease Genes
  3. PLCG1

PLCG1 gene related symptoms and diseases

All the information presented here about the PLCG1 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,NCBIGENE,OMIM, Mendelian Rare Disease Search Engine.

Table of contents:

Top 5 symptoms and clinical features associated to PLCG1 gene

Symptoms // Phenotype % Cases
Neoplasm Very Common - Between 80% and 100% cases
Lymphadenopathy Very Common - Between 80% and 100% cases
Abnormal immunoglobulin level Very Common - Between 80% and 100% cases
Abnormal lymphocyte morphology Very Common - Between 80% and 100% cases
T-cell lymphoma Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with PLCG1 gene alterations may also develop some of the following symptoms and phenotypes:

  • Commonly - More than 50% cases

  • Lichenification
  • Abnormality of the pleura
  • Gangrene
  • Irregular hyperpigmentation
  • Erythroderma
  • Ectropion
  • Neoplasm of the skin
  • Thickened skin

And 21 more phenotypes, you can get all of them using our tools for rare diseases.

Rare diseases associated to PLCG1 gene

Here you will find a list of rare diseases related to the PLCG1. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


SÉZARY SYNDROME

Alternate names

SÉZARY SYNDROME Is also known as sÉzary lymphoma

Description

Sézary syndrome (SS) is an aggressive form of cutaneous T-cell lymphoma characterized by a triad of erythroderma, lymphadenopathy and circulating atypical lymphocytes (Sézary cells).

Most common symptoms of SÉZARY SYNDROME

  • Neoplasm
  • Abnormal facial shape
  • Peripheral neuropathy
  • Hepatomegaly
  • Fever


More info about SÉZARY SYNDROME

SOURCES: MESH ORPHANET


Potential gene panels for PLCG1 gene

PLCG1 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the PLCG1 gene.

More info about this panel
United States.

Tempus xO assay Panel

United States.

By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2

More info about this panel
United States.

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