OGG1 gene related symptoms and diseases
All the information presented here about the OGG1 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,NCBIGENE,HGNC,ORPHANET, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to OGG1 gene
Symptoms // Phenotype | % Cases |
---|---|
Neoplasm | Uncommon - Between 30% and 50% cases |
Renal neoplasm | Uncommon - Between 30% and 50% cases |
Cerebellar hemangioblastoma | Uncommon - Between 30% and 50% cases |
Small cell lung carcinoma | Uncommon - Between 30% and 50% cases |
Clear cell renal cell carcinoma | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with OGG1 gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Burkitt lymphoma
- Fibrosarcoma
- Papillary renal cell carcinoma
- Retinoblastoma
- Renal cell carcinoma
- Hypertension
- Polycythemia
- Nephroblastoma
And 7 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to OGG1 gene
Here you will find a list of rare diseases related to the OGG1. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
RENAL CELL CARCINOMA, NONPAPILLARY; RCC
Alternate names
RENAL CELL CARCINOMA, NONPAPILLARY; RCC Is also known as hypernephroma, adenocarcinoma of kidney
Description
The Heidelberg histologic classification of renal cell tumors subdivides renal cell tumors into benign and malignant parenchymal neoplasms and, where possible, limits each subcategory to the most common documented genetic abnormalities (Kovacs et al., 1997). Malignant tumors are subclassified into common or conventional renal cell carcinoma (clear cell); papillary renal cell carcinoma; chromophobe renal cell carcinoma; collecting duct carcinoma, with medullary carcinoma of the kidney; and unclassified renal cell carcinoma. The common or conventional type accounts for about 75% of renal cell neoplasms and is characterized genetically by a highly specific deletion of chromosome 3p. Papillary renal cell carcinoma (see {605074}) accounts for about 10% of renal cell tumors. Chromophobe renal cell carcinoma accounts for approximately 5% of renal cell neoplasms. Genetically, chromophobe RCC is characterized by a combination of loss of heterozygosity of chromosomes 1, 2, 6, 10, 13, 17, and 21 and hypodiploid DNA content. Collecting duct carcinoma accounts for about 1% of renal cell carcinoma.Renal cell carcinoma occurs nearly twice as often in men as in women; incidence in the United States is equivalent among whites and blacks. Cigarette smoking doubles the likelihood of renal cell carcinoma and contributes to as many as one-third of cases. Obesity is also a risk factor, particularly in women. Other risk factors include hypertension, unopposed estrogen therapy, and occupational exposure to petroleum products, heavy metals, or asbestos (summary by Motzer et al., 1996).
Most common symptoms of RENAL CELL CARCINOMA, NONPAPILLARY; RCC
- Neoplasm
- Hypertension
- Obesity
- Carcinoma
- Falls
HEREDITARY CLEAR CELL RENAL CELL CARCINOMA
Alternate names
HEREDITARY CLEAR CELL RENAL CELL CARCINOMA Is also known as hereditary clear cell renal cell adenocarcinoma
Description
Hereditary clear cell renal cell carcinoma (ccRCC) is a hereditary renal cancer syndrome defined as development of ccRCC in two or more family members without evidence of constitutional chromosome 3 translocation, von Hippel-Lindau disease or other tumor predisposing syndromes associated with ccRCC, such as tuberous sclerosis or Birt-Hogg-Dubbé syndrome.
More info about HEREDITARY CLEAR CELL RENAL CELL CARCINOMASOURCES: ORPHANET
Search interest in OGG1
Potential gene panels for OGG1 gene
MitoMet®Plus aCGH Analysis Panel
By Baylor Miraca Genetics Laboratories MitoMet®Plus aCGH Analysis that also includes the following genes: RGS9 RHO GRK1 RLBP1 RNASEL BCS1L RP1 RP2 RP9 RPE65
More info about this panelComprehensive mitochondrial disorders panel Panel
By Centogene AG - the Rare Disease Company Comprehensive mitochondrial disorders panel that also includes the following genes: RNASEL BCS1L MRPL3 SARDH SCO1 SCO2 SCP2 SDHA SDHB SDHC
More info about this panelNuclear-Mito NGS Panel Panel
By Fulgent Genetics Fulgent Genetics Nuclear-Mito NGS Panel that also includes the following genes: RNASEL BCS1L RPL35A MRPL3 RYR1 RYR2 SACS ACSM3 SARDH ATXN7
More info about this panelOGG1 Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the OGG1 gene.
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