MUC5B gene related symptoms and diseases
All the information presented here about the MUC5B gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,NCBIGENE,ORPHANET,HGNC, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to MUC5B gene
Symptoms // Phenotype | % Cases |
---|---|
Bronchiectasis | Very Common - Between 80% and 100% cases |
Respiratory insufficiency | Very Common - Between 80% and 100% cases |
Exertional dyspnea | Very Common - Between 80% and 100% cases |
Respiratory failure | Very Common - Between 80% and 100% cases |
Dyspnea | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with MUC5B gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Clubbing
- Cough
- Crackles
Not very common - Between 30% and 50% cases
- Neoplasm
- Hypocapnia
- Reticular pattern on pulmonary HRCT
- Honeycomb lung
- Ground-glass opacification on pulmonary HRCT
And 39 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to MUC5B gene
Here you will find a list of rare diseases related to the MUC5B. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
IDIOPATHIC PULMONARY FIBROSIS
Alternate names
IDIOPATHIC PULMONARY FIBROSIS Is also known as cfa, uip, usual interstitial pneumonia, interstitial pneumonitis, usual, idiopathic pulmonary fibrosis, familial, cryptogenic fibrosing alveolitis, fibrosing alveolitis, cryptogenic, fibrocystic pulmonary dysplasia
Description
Idiopathic pulmonary fibrosis (IPF) is a nonneoplastic pulmonary disease that is characterized by the formation of scar tissue within the lungs in the absence of any known cause.
Most common symptoms of IDIOPATHIC PULMONARY FIBROSIS
- Neoplasm
- Hypertension
- Fever
- Respiratory insufficiency
- Respiratory distress
More info about IDIOPATHIC PULMONARY FIBROSIS
DIFFUSE PANBRONCHIOLITIS
Alternate names
DIFFUSE PANBRONCHIOLITIS Is also known as pblt, dpb
Description
Diffuse panbronchiolitis is a rare chronic inflammatory obstructive pulmonary disease primarily affecting the respiratory bronchioles throughout both lungs and inducing sinobronchial infection. Onset occurs in the second to fifth decade of life and manifests by chronic cough, exertional dyspnea, and sputum production. Most patients also have chronic paranasal sinusitis
Most common symptoms of DIFFUSE PANBRONCHIOLITIS
- Respiratory insufficiency
- Dilatation
- Respiratory failure
- Weight loss
- Dyspnea
More info about DIFFUSE PANBRONCHIOLITIS
Search interest in MUC5B
Potential gene panels for MUC5B gene
Comprehensive Pulmonary Panel Panel
By Greenwood Genetic Center Diagnostic Laboratories Greenwood Genetic Center Comprehensive Pulmonary Panel that also includes the following genes: RPGR SCNN1A SCNN1B SCNN1G BMPR1B BMPR2 SFTPA1 SFTPA2 SFTPB SFTPC
More info about this panelHermansky-Pudlak and Pulmonary Fibrosis Panel Panel
By Greenwood Genetic Center Diagnostic Laboratories Greenwood Genetic Center Hermansky-Pudlak and Pulmonary Fibrosis Panel that also includes the following genes: SFTPA1 SFTPA2 SFTPB SFTPC SFTPD TERC TERT TINF2 NKX2-1 HPS3
More info about this panelBasic Fibrosis Panel (12 Genes) Panel
By Laboratory for Molecular Medicine Partners HealthCare Personalized Medicine Basic Fibrosis Panel (12 Genes) that also includes the following genes: SFTPA1 SFTPA2 SFTPB SFTPC SFTPD TERC TERT NKX2-1 CSF2RA ELMOD2
More info about this panelPulmoGene Panel (64 Genes) Panel
By Laboratory for Molecular Medicine Partners HealthCare Personalized Medicine PulmoGene Panel (64 Genes) that also includes the following genes: RPGR BDNF SCNN1A SCNN1B SCNN1G BMPR2 SFTPA1 SFTPA2 SFTPB SFTPC
More info about this panelPulmonary Fibrosis - Hermansky Pudlak Panel (21 Genes) Panel
By Laboratory for Molecular Medicine Partners HealthCare Personalized Medicine Pulmonary Fibrosis - Hermansky Pudlak Panel (21 Genes) that also includes the following genes: SFTPA1 SFTPA2 SFTPB SFTPC SFTPD TERC TERT NKX2-1 HPS3 HPS4
More info about this panelPulmonary fibrosis, idiopathic (sequence analysis of MUC5B gene) Panel
By CGC Genetics
This panel specifically test the MUC5B gene.
More info about this panelComprehensive pulmonary disease panel Panel
By Centogene AG - the Rare Disease Company Comprehensive pulmonary disease panel that also includes the following genes: BDNF SCNN1A SCNN1B SCNN1G BMPR2 SFTPA1 SFTPA2 SFTPB SFTPC SFTPD
More info about this panelPulmonary fibrosis, idiopathic, and Surfactant protein deficiency Panel
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases Pulmonary fibrosis, idiopathic, and Surfactant protein deficiency that also includes the following genes: SFTPA2 SFTPB SFTPC SFTPD TERC TERT CSF2RA CSF2RB DMBT1 ABCA3
More info about this panelPulmonary Disease: Comprehensive Sequencing Panel Panel
By EGL Genetic Diagnostics Eurofins Clinical Diagnostics Pulmonary Disease: Comprehensive Sequencing Panel that also includes the following genes: BDNF SCNN1A SCNN1B SCNN1G BMPR2 SFTPB SFTPC SFTPD STAT3 TERT
More info about this panelPulmonary Fibrosis and Hermansky-Pudlak Syndrome: Sequencing Panel Panel
By EGL Genetic Diagnostics Eurofins Clinical Diagnostics Pulmonary Fibrosis and Hermansky-Pudlak Syndrome: Sequencing Panel that also includes the following genes: SFTPA1 SFTPB SFTPC SFTPD TERT HPS3 HPS4 DTNBP1 HPS6 BLOC1S3
More info about this panelLung Disorders NGS Panel Panel
By Fulgent Genetics Fulgent Genetics Lung Disorders NGS Panel that also includes the following genes: BDNF SCNN1A SCNN1B SCNN1G BMPR2 SFTPA1 SFTPA2 SFTPB SFTPC TERC
More info about this panelMUC5B Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the MUC5B gene.
More info about this panelPULMONARY FIBROSIS, IDIOPATHIC Panel
By Laboratorio de Genetica Clinica SL PULMONARY FIBROSIS, IDIOPATHIC that also includes the following genes: SFTPA2 SFTPC TERC TERT RTEL1 MUC5B PARN
More info about this panelFamilial Pulmonary Fibrosis and Pulmonary Surfactant Metabolism Dysfunction , Panel Massive Sequencing (NGS) 9 Genes Panel
By Reference Laboratory Genetics Familial Pulmonary Fibrosis and Pulmonary Surfactant Metabolism Dysfunction , Panel Massive Sequencing (NGS) 9 Genes that also includes the following genes: SFTPA2 SFTPB SFTPC TERC TERT CSF2RA CSF2RB ABCA3 MUC5B
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