MSH3 gene related symptoms and diseases
All the information presented here about the MSH3 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,ORPHANET,HGNC,NCBIGENE, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to MSH3 gene
Symptoms // Phenotype | % Cases |
---|---|
Neoplasm | Uncommon - Between 30% and 50% cases |
Carcinoma | Uncommon - Between 30% and 50% cases |
Astrocytoma | Uncommon - Between 30% and 50% cases |
Stomach cancer | Uncommon - Between 30% and 50% cases |
Papilloma | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with MSH3 gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Thyroid adenoma
- Endometrial carcinoma
Rare diseases associated to MSH3 gene
Here you will find a list of rare diseases related to the MSH3. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
MSH3-RELATED ATTENUATED FAMILIAL ADENOMATOUS POLYPOSIS
Alternate names
MSH3-RELATED ATTENUATED FAMILIAL ADENOMATOUS POLYPOSIS Is also known as msh3-related attenuated familial polyposis coli, msh3-related attenuated fap, msh3-related afap
Description
Familial adenomatous polyposis-4 is an autosomal recessive tumor predisposition syndrome characterized by the development of multiple colonic adenomas in adulthood, often with progression to colorectal cancer. Proliferative lesions in other tissues may also occur (summary by Adam et al., 2016).For a discussion of genetic heterogeneity of familial adenomatous polyposis, see FAP1 (OMIM ).
Most common symptoms of MSH3-RELATED ATTENUATED FAMILIAL ADENOMATOUS POLYPOSIS
- Neoplasm
- Carcinoma
- Astrocytoma
- Stomach cancer
- Papilloma
More info about MSH3-RELATED ATTENUATED FAMILIAL ADENOMATOUS POLYPOSIS
ENDOMETRIAL CANCER
Description
Cancer that forms in the tissue lining the uterus (the small, hollow, pear-shaped organ in a woman's pelvis in which a fetus develops). Most endometrial cancers are adenocarcinomas (cancers that begin in cells that make and release mucus and other fluids).
Most common symptoms of ENDOMETRIAL CANCER
- Endometrial carcinoma
More info about ENDOMETRIAL CANCER
SOURCES: OMIM
Search interest in MSH3
Potential gene panels for MSH3 gene
Hereditary Cancer Panel- Comprehensive63 Panel
By Human Genetics Laboratory, Munroe-Meyer Institute University of Nebraska Medical Center Hereditary Cancer Panel- Comprehensive63 that also includes the following genes: BLM SDHA SDHB SDHC SDHD BMPR1A BRCA1 BRCA2 SMARCA4 STK11
More info about this panelEndometrial carcinoma, somatic (sequence analysis of MSH3 gene) Panel
By CGC Genetics
This panel specifically test the MSH3 gene.
More info about this panelHereditary colon cancer (panel NGS of 21 genes) Panel
By CGC Genetics Hereditary colon cancer (panel NGS of 21 genes) that also includes the following genes: BMPR1A STK11 EPCAM TGFBR2 TP53 CDH1 GALNT12 APC SMAD4 MLH1
More info about this panelHereditary nonpolyposis colorectal cancer (metilation analysis and deletions/duplications analysis of MLH1, MLH3, MSH2, MSH3, MSH6, PMS2 and MGMT by MS-MLPA) Panel
By CGC Genetics Hereditary nonpolyposis colorectal cancer (metilation analysis and deletions/duplications analysis of MLH1, MLH3, MSH2, MSH3, MSH6, PMS2 and MGMT by MS-MLPA) that also includes the following genes: MLH1 MLH3 MSH2 MSH3 MSH6 PMS2
More info about this panelHereditary nonpolyposis colorectal cancer (metilation analysis and deletions/duplications analysis of MLH1, MLH3, MSH2, MSH3, MSH6, PMS2 and MGMT by MS-MLPA) Panel
By CGC Genetics Hereditary nonpolyposis colorectal cancer (metilation analysis and deletions/duplications analysis of MLH1, MLH3, MSH2, MSH3, MSH6, PMS2 and MGMT by MS-MLPA) that also includes the following genes: MLH1 MLH3 MSH2 MSH3 MSH6 PMS2
More info about this panelHereditary colon cancer (panel NGS of 21 genes) Panel
By CGC Genetics Hereditary colon cancer (panel NGS of 21 genes) that also includes the following genes: BMPR1A STK11 EPCAM TGFBR2 TP53 CDH1 GALNT12 APC SMAD4 MLH1
More info about this panelCancer Sequencing Panel with CNV Detection Panel
By PreventionGenetics PreventionGenetics Cancer Sequencing Panel with CNV Detection that also includes the following genes: RUNX1 BLM SDHA SDHB SDHC SDHD BMPR1A BRCA1 BRCA2 SMARCA4
More info about this panelHereditary Polyposis Sequencing Panel with CNV Detection Panel
By PreventionGenetics PreventionGenetics Hereditary Polyposis Sequencing Panel with CNV Detection that also includes the following genes: APC MSH3 MUTYH NTHL1 POLD1 POLE
More info about this panelHnpcc Deep Intronic Panel
By MGZ Medical Genetics Center Hnpcc Deep Intronic that also includes the following genes: EPCAM MLH1 MLH3 MSH2 MSH3 MSH6 PMS1 PMS2
More info about this panelEndometrial carcinoma Panel
By Centogene AG - the Rare Disease Company
This panel specifically test the MSH3 gene.
More info about this panelMMR genes methylation analysis Panel
By Centogene AG - the Rare Disease Company MMR genes methylation analysis that also includes the following genes: MGMT MLH1 MLH3 MSH2 MSH3 MSH6 PMS2
More info about this panelBreast and Ovarian Cancer - extended Diagnostic Panel Panel
By CeGaT GmbH Breast and Ovarian Cancer - extended Diagnostic Panel that also includes the following genes: SDHB SDHC SDHD BRCA1 BRCA2 STK11 EPCAM TP53 XRCC2 CDH1
More info about this panelSingle gene testing MSH3 Panel
By CeGaT GmbH
This panel specifically test the MSH3 gene.
More info about this panelCOLON CANCER Panel
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases COLON CANCER that also includes the following genes: BMPR1A STK11 EPCAM FLCN ENG APC SMAD4 MLH1 MSH2 MSH3
More info about this panelHereditary Cancer NGS Panel Panel
By Fulgent Genetics Fulgent Genetics Hereditary Cancer NGS Panel that also includes the following genes: ROBO2 BLM SDHA SDHB SDHC SDHD BMPR1A BRCA1 BRCA2 SMARCB1
More info about this panelComprehensive Cancer Panel Panel
By Fulgent Genetics Fulgent Genetics Comprehensive Cancer Panel that also includes the following genes: ROBO2 RUNX1 BLM SDHA SDHB SDHC SDHD BMPR1A BRCA1 BRCA2
More info about this panelMSH3 Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the MSH3 gene.
More info about this panelFoundationOne® Heme Panel
By Foundation Medicine, Inc. FoundationOne® Heme that also includes the following genes: BCL6 BCL7A ROS1 RUNX1 BLM SDHA SDHB SDHC SDHD SF3B1
More info about this panelCOLORECTAL CANCER HEREDITARY NGS PANEL Panel
By Laboratorio de Genetica Clinica SL COLORECTAL CANCER HEREDITARY NGS PANEL that also includes the following genes: BMPR1A STK11 EPCAM TGFBR2 TP53 GREM1 APC SMAD4 MLH1 MLH3
More info about this panelBREAST AND OVARIAN CANCER NGS PANEL Panel
By Laboratorio de Genetica Clinica SL BREAST AND OVARIAN CANCER NGS PANEL that also includes the following genes: BLM BRCA1 BRCA2 STK11 EPCAM TP53 WRN CDH1 PSMC3IP TNFRSF13B
More info about this panelPOLYPOSIS, FAMILIAL ADENOMATOUS (FAP) & POLYPOSIS, JUVENILE NGS PANEL Panel
By Laboratorio de Genetica Clinica SL POLYPOSIS, FAMILIAL ADENOMATOUS (FAP) & POLYPOSIS, JUVENILE NGS PANEL that also includes the following genes: BMPR1A APC SMAD4 MSH3 MUTYH AXIN2 PTEN
More info about this panelHereditary Colon Cancer , Panel Massive Sequencing (NGS) 14 Genes Panel
By Reference Laboratory Genetics Hereditary Colon Cancer , Panel Massive Sequencing (NGS) 14 Genes that also includes the following genes: BMPR1A STK11 EPCAM FLCN ENG APC SMAD4 MLH1 MSH2 MSH3
More info about this panelTempus xT assay Panel
By Tempus Labs, Inc. Tempus xT assay that also includes the following genes: BCL6 RIT1 BCL7A BCR ROS1 RPL5 RPS15 RPS6KB1 RUNX1 RXRA
More info about this panelTempus xO assay Panel
By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2
More info about this panelCEN4GEN Colorectal cancer: Extended Sequencing Panel Panel
By CEN4GEN Institute for Genomics and Molecular Diagnostics CEN4GEN Colorectal cancer: Extended Sequencing Panel that also includes the following genes: BRAF TCF7L2 TGFBR2 TP53 CASP8 TCERG1 GALNT17 FBXW7 ACVR1B CDC27
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