MN1 gene related symptoms and diseases
All the information presented here about the MN1 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,HGNC,OMIM,ORPHANET, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to MN1 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Neoplasm | Uncommon - Between 30% and 50% cases |
| Meningioma | Uncommon - Between 30% and 50% cases |
| Medulloblastoma | Uncommon - Between 30% and 50% cases |
| Neoplasm of the central nervous system | Uncommon - Between 30% and 50% cases |
Rare diseases associated to MN1 gene
Here you will find a list of rare diseases related to the MN1. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
MENINGIOMA, FAMILIAL, SUSCEPTIBILITY TO
Description
Meningiomas are, in general, slowly growing benign tumors derived from the arachnoidal cap cells of the leptomeninges, the soft coverings of the brain and spinal cord. Meningiomas are believed to be the most common primary tumors of the central nervous system in man. The vast majority of meningiomas are sporadic; familial occurrence of meningioma is rare (Zang, 2001).Familial or multiple meningiomas may also be seen in tumor predisposition syndromes. Some patients with schwannomatosis (OMIM ), caused by mutation in the SMARCB1 gene, may develop meningiomas. One patient with malignant gliomas (GLM2 ) associated with a mutation in the PTEN gene (OMIM ) developed a meningioma (Staal et al., 2002).
Most common symptoms of MENINGIOMA, FAMILIAL, SUSCEPTIBILITY TO
- Neoplasm
- Meningioma
- Medulloblastoma
- Neoplasm of the central nervous system
More info about MENINGIOMA, FAMILIAL, SUSCEPTIBILITY TO
FAMILIAL MULTIPLE MENINGIOMA
Description
Familial multiple meningioma is a rare, benign neoplasm of the central nervous system characterized by the development of multiple or, rarely, solitary meningiomas in two or more blood relatives, without other apparent syndromic manifestations. Depending on the localization, growth rate and size of the tumors, patients can present with subtle, gradually worsening or abrupt and severe neurological compromise or can be completely asymptomatic.
More info about FAMILIAL MULTIPLE MENINGIOMA
SOURCES: ORPHANET
Search interest in MN1
Potential gene panels for MN1 gene
RT-PCR t(12;22) (TEL/MN1) Panel
Portugal.
By CGC Genetics RT-PCR t(12;22) (TEL/MN1) that also includes the following genes: ETV6 MN1
More info about this panel Portugal.
Meningioma Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the MN1 gene.
More info about this panel Germany.
FAMILIAL MULTIPLE MENINGIOMA Panel
Spain.
By Hereditary Cancer Group - Genetic Diagnostic Unit Germans Trias I Pujol Research Institute FAMILIAL MULTIPLE MENINGIOMA that also includes the following genes: SMARCE1 SUFU MN1 NF2 PDGFB PTEN
More info about this panel Spain.
Meningioma, Familial multiple: MN1 gene sequence analysis Panel
Spain.
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases
This panel specifically test the MN1 gene.
More info about this panel Spain.
Solid Tumor Gene Set Panel
United States.
By Genomics and Pathology Services Washington University in St. Louis Solid Tumor Gene Set that also includes the following genes: RIT1 ROS1 RXRA FOXL2 BRAF BRCA1 BRCA2 SMARCA4 SMARCB1 KDM5C
More info about this panel United States.
CNS Tumor Gene Set Panel
United States.
By Genomics and Pathology Services Washington University in St. Louis CNS Tumor Gene Set that also includes the following genes: SHH BRAF SMARCA4 SMARCB1 SMO TERT MED12 TP53 WNT1 WT1
More info about this panel United States.
Caris MI TumorSeek 592-Gene NGS Panel Panel
United States.
By Caris Life Sciences Caris MI TumorSeek 592-Gene NGS Panel that also includes the following genes: BCL6 BCL7A BCL9 BCR ROS1 RPL10 RPL22 RPL5 RPN1 RUNX1
More info about this panel United States.
Familiy Multiple Meningioma , Sequencing MN1 Gene Panel
Spain.
By Reference Laboratory Genetics
This panel specifically test the MN1 gene.
More info about this panel Spain.
Familial Meningioma , Panel Massive Sequencing (NGS) 6 Genes Panel
Spain.
By Reference Laboratory Genetics Familial Meningioma , Panel Massive Sequencing (NGS) 6 Genes that also includes the following genes: SMARCE1 SUFU MN1 NF2 PDGFB PTEN
More info about this panel Spain.
Tempus xO assay Panel
United States.
By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2
More info about this panel United States.
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