MGMT gene related symptoms and diseases
All the information presented here about the MGMT gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,HGNC,NCBIGENE,OMIM, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to MGMT gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Retinopathy | Uncommon - Between 30% and 50% cases |
| Dry skin | Uncommon - Between 30% and 50% cases |
| Nevus | Uncommon - Between 30% and 50% cases |
| Abnormality of extrapyramidal motor function | Uncommon - Between 30% and 50% cases |
| Abnormality of the hair | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with MGMT gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Melanoma
- Freckling
- Neoplasm of the pancreas
- Abnormality of the lymphatic system
- Neoplasm of the breast
- Neoplasm of the stomach
Rare diseases associated to MGMT gene
Here you will find a list of rare diseases related to the MGMT. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
GLIOSARCOMA
GIANT CELL GLIOBLASTOMA
FAMILIAL MELANOMA
Description
Familial melanoma (FM) is a rare inherited form of melanoma characterized by development of histologically confirmed melanoma in two first degrees relatives or more relatives in an affected family.
Most common symptoms of FAMILIAL MELANOMA
- Retinopathy
- Dry skin
- Nevus
- Abnormality of extrapyramidal motor function
- Abnormality of the hair
More info about FAMILIAL MELANOMA
SOURCES: ORPHANET
Search interest in MGMT
Potential gene panels for MGMT gene
MGMT Promoter Methylation assay Panel
United States.
By UCSF Molecular Diagnostics Laboratory University of California, San Francisco
This panel specifically test the MGMT gene.
More info about this panel United States.
HopeSeq Glioma Panel
United States.
By Clinical Molecular Diagnostic Laboratory City of Hope National Medical Center
This panel specifically test the MGMT gene.
More info about this panel United States.
Glioma (methilation analysis of MGMT gene promoter and frequent mutations on IDH1 e IDH2 genes) Panel
Portugal.
By CGC Genetics Glioma (methilation analysis of MGMT gene promoter and frequent mutations on IDH1 e IDH2 genes) that also includes the following genes: IDH1 IDH2 MGMT
More info about this panel Portugal.
Glioma (methilation analysis of MGMT gene promoter and frequent mutations on IDH1 e IDH2 genes) Panel
Portugal.
By CGC Genetics Glioma (methilation analysis of MGMT gene promoter and frequent mutations on IDH1 e IDH2 genes) that also includes the following genes: IDH1 IDH2 MGMT
More info about this panel Portugal.
MGMT promoter methylation Panel
United States.
By Molecular Diagnostics Laboratory University of Toledo Medical Center
This panel specifically test the MGMT gene.
More info about this panel United States.
MMR genes methylation analysis Panel
Germany.
By Centogene AG - the Rare Disease Company MMR genes methylation analysis that also includes the following genes: MGMT MLH1 MLH3 MSH2 MSH3 MSH6 PMS2
More info about this panel Germany.
Hereditary Cancer Syndrome: Sequencing Panel Panel
United States.
By EGL Genetic Diagnostics Eurofins Clinical Diagnostics Hereditary Cancer Syndrome: Sequencing Panel that also includes the following genes: BLM SDHB SDHC SDHD BMPR1A BRCA1 BRCA2 SMARCA4 SMARCB1 STK11
More info about this panel United States.
MGMT Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the MGMT gene.
More info about this panel United States.
Tempus xT assay Panel
United States.
By Tempus Labs, Inc. Tempus xT assay that also includes the following genes: BCL6 RIT1 BCL7A BCR ROS1 RPL5 RPS15 RPS6KB1 RUNX1 RXRA
More info about this panel United States.
Tempus xO assay Panel
United States.
By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2
More info about this panel United States.
Melanoma: Gene Sequencing Panel Panel
Canada.
By CEN4GEN Institute for Genomics and Molecular Diagnostics Melanoma: Gene Sequencing Panel that also includes the following genes: BRCA1 TP53 WRN CDK4 CDKN2A KIT MGMT NRAS BAP1 PTEN
More info about this panel Canada.
Hereditary Cancer Syndrome: Gene Sequencing Panel Panel
Canada.
By CEN4GEN Institute for Genomics and Molecular Diagnostics Hereditary Cancer Syndrome: Gene Sequencing Panel that also includes the following genes: BLM SDHB SDHC SDHD BMPR1A BRCA1 BRCA2 SMARCA4 SMARCB1 STK11
More info about this panel Canada.
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