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MEIS2 gene related symptoms and diseases

All the information presented here about the MEIS2 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,NCBIGENE,ORPHANET,HGNC, Mendelian Rare Disease Search Engine.

Table of contents:

Top 5 symptoms and clinical features associated to MEIS2 gene

Symptoms // Phenotype % Cases
Intellectual disability Very Common - Between 80% and 100% cases
Atrial septal defect Very Common - Between 80% and 100% cases
Narrow forehead Very Common - Between 80% and 100% cases
Abnormal cardiac septum morphology Very Common - Between 80% and 100% cases
Cleft lip Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with MEIS2 gene alterations may also develop some of the following symptoms and phenotypes:

  • Commonly - More than 50% cases

  • Deeply set eye
  • Tented upper lip vermilion
  • Global developmental delay
  • Highly arched eyebrow
  • Oral cleft
  • Ventricular septal defect
  • Motor delay
  • Low-set ears

And 58 more phenotypes, you can get all of them using our tools for rare diseases.

Rare diseases associated to MEIS2 gene

Here you will find a list of rare diseases related to the MEIS2. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


CLEFT PALATE, CARDIAC DEFECTS, AND MENTAL RETARDATION; CPCMR

Alternate names

CLEFT PALATE, CARDIAC DEFECTS, AND MENTAL RETARDATION; CPCMR Is also known as cardiac malformation, cleft lip/palate, microcephaly, and digital anomalies

Most common symptoms of CLEFT PALATE, CARDIAC DEFECTS, AND MENTAL RETARDATION; CPCMR

  • Intellectual disability
  • Global developmental delay
  • Short stature
  • Microcephaly
  • Abnormal facial shape


More info about CLEFT PALATE, CARDIAC DEFECTS, AND MENTAL RETARDATION; CPCMR

SOURCES: MESH OMIM

15Q14 MICRODELETION SYNDROME

Alternate names

15Q14 MICRODELETION SYNDROME Is also known as del(15)(q14), monosomy 15q14

Description

15q14 microdeletion syndrome is a recently described syndrome characterized by developmental delay, short stature and facial dysmorphism.

Most common symptoms of 15Q14 MICRODELETION SYNDROME

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Short stature
  • Generalized hypotonia


More info about 15Q14 MICRODELETION SYNDROME

SOURCES: OMIM ORPHANET


Potential gene panels for MEIS2 gene

Mental retardation - different panels Panel

Germany.

By Institute of Human Genetics Uniklinik RWTH Aachen Mental retardation - different panels that also includes the following genes: RGS7 RIT1 RMRP BCS1L RPL10 RPS6KA3 RRAS SALL1 SC5D ATXN10

More info about this panel
Germany.

Invitae Congenital Heart Defects and Heterotaxy Panel Panel

United States.

By Invitae Invitae Congenital Heart Defects and Heterotaxy Panel that also includes the following genes: RIT1 RPGR BRAF SOS1 SPAG1 TBX1 TBX5 RSPH1 ZIC3 CFAP298

More info about this panel
United States.

Invitae Congenital Heart Disease Panel Panel

United States.

By Invitae Invitae Congenital Heart Disease Panel that also includes the following genes: RIT1 BRAF SOS1 TBX1 TBX5 ZIC3 NSD1 ACTC1 CRELD1 CBL

More info about this panel
United States.

MEIS2 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the MEIS2 gene.

More info about this panel
United States.

Congenital Structural Heart Disease Panel Panel

Finland.

By Blueprint Genetics Congenital Structural Heart Disease Panel that also includes the following genes: BMPR2 SOS2 TBX1 TBX20 TBX5 TFAP2B TLL1 ZIC3 ACTA2 ACTB

More info about this panel
Finland.

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