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  1. Mendelian
  2. Rare Disease Genes
  3. MCC

MCC gene related symptoms and diseases

All the information presented here about the MCC gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,NCBIGENE,OMIM, Mendelian Rare Disease Search Engine.

Table of contents:

Top 5 symptoms and clinical features associated to MCC gene

Symptoms // Phenotype % Cases
Intellectual disability Uncommon - Between 30% and 50% cases
Left ventricular failure Uncommon - Between 30% and 50% cases
Chronic hemolytic anemia Uncommon - Between 30% and 50% cases
Hypochromic anemia Uncommon - Between 30% and 50% cases
Chronic myelogenous leukemia Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with MCC gene alterations may also develop some of the following symptoms and phenotypes:

  • Not very common - Between 30% and 50% cases

  • Microalbuminuria
  • Abnormal hemoglobin
  • Night sweats
  • Abnormality of the spleen
  • Hypoxemia
  • Pure red cell aplasia
  • Increased mean corpuscular volume
  • Atelectasis

And 72 more phenotypes, you can get all of them using our tools for rare diseases.

Rare diseases associated to MCC gene

Here you will find a list of rare diseases related to the MCC. You can also use our tool to get a more accurate diagnosis based on your current symptoms.

SICKLE CELL ANEMIA

Alternate names

SICKLE CELL ANEMIA Is also known as sickle cell disease

Description

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Most common symptoms of SICKLE CELL ANEMIA

  • Intellectual disability
  • Pain
  • Anemia
  • Hypertension
  • Hepatomegaly
More info about SICKLE CELL ANEMIA

SOURCES: OMIM MESH ORPHANET

COLORECTAL CANCER; CRC

Alternate names

COLORECTAL CANCER; CRC Is also known as colon cancer

Description

Colorectal cancer is a heterogeneous disease that is common in both men and women. In addition to lifestyle and environmental risk factors, gene defects can contribute to an inherited predisposition to CRC. CRC is caused by changes in different molecular pathogenic pathways, such as chromosomal instability, CpG island methylator phenotype, and microsatellite instability. Chromosome instability is the most common alteration and is present in almost 85% of all cases (review by Schweiger et al., 2013).

Most common symptoms of COLORECTAL CANCER; CRC

  • Neoplasm
  • Carcinoma
  • Oligodontia
  • Colon cancer
  • Colitis
More info about COLORECTAL CANCER; CRC

SOURCES: OMIM

Potential gene panels for MCC gene

MCC Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the MCC gene.

More info about this panel
United States.

PrimBio Colorectal Cancer Panel Panel

United States.

By PrimBio Research Institute PrimBio Research Institute PrimBio Colorectal Cancer Panel that also includes the following genes: BLM BMPR1A SCG5 BRAF BRCA1 STK11 BUB1B EPCAM TCF7L2 TGFBR2

More info about this panel
United States.

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