MAP3K8 gene related symptoms and diseases

All the information presented here about the MAP3K8 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,HGNC,NCBIGENE, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to MAP3K8 gene

Symptoms // Phenotype % Cases
Neoplasm Very Common - Between 80% and 100% cases
Sarcoma Very Common - Between 80% and 100% cases
Alveolar cell carcinoma Very Common - Between 80% and 100% cases
Small cell lung carcinoma Very Common - Between 80% and 100% cases
Lung adenocarcinoma Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with MAP3K8 gene alterations may also develop some of the following symptoms and phenotypes:
  • Commonly - More than 50% cases

  • Neoplasm of the lung
  • Hemoptysis
  • Wheezing
  • Squamous cell carcinoma
  • Chest pain
  • Pain
  • Leukemia
  • Cough

And 6 more phenotypes, you can get all of them using our tools for rare diseases.

Rare diseases associated to MAP3K8 gene

Here you will find a list of rare diseases related to the MAP3K8. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


LUNG CANCER

Description

Lung cancer is the leading cause of cancer deaths in the U.S. and worldwide. The 2 major forms of lung cancer are nonsmall cell lung cancer and small cell lung cancer (see {182280}), which account for 85% and 15% of all lung cancers, respectively. Nonsmall cell lung cancer can be divided into 3 major histologic subtypes: squamous cell carcinoma, adenocarcinoma, and large cell lung cancer. Cigarette smoking causes all types of lung cancer, but it is most strongly linked with small cell lung cancer and squamous cell carcinoma. Adenocarcinoma is the most common type in patients who have never smoked. Nonsmall cell lung cancer is often diagnosed at an advanced stage and has a poor prognosis (summary by Herbst et al., 2008).

Most common symptoms of LUNG CANCER

  • Neoplasm
  • Pain
  • Fatigue
  • Respiratory distress
  • Diarrhea


More info about LUNG CANCER

SOURCES: OMIM


Potential gene panels for MAP3K8 gene

Noonan Spectrum Disorders/Rasopathies Sequencing Panel with CNV Detection Panel

United States.

By PreventionGenetics PreventionGenetics Noonan Spectrum Disorders/Rasopathies Sequencing Panel with CNV Detection that also includes the following genes: RIT1 RRAS BRAF SOS1 SOS2 SPRY1 CBL SHOC2 KAT6B A2ML1

More info about this panel
United States.

MAP3K8 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the MAP3K8 gene.

More info about this panel
United States.

Tempus xO assay Panel

United States.

By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2

More info about this panel
United States.

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