LRP6 gene related symptoms and diseases
All the information presented here about the LRP6 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,NCBIGENE,HGNC,OMIM, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to LRP6 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Oligodontia | Common - Between 50% and 80% cases |
| Hypertension | Uncommon - Between 30% and 50% cases |
| Glucose intolerance | Uncommon - Between 30% and 50% cases |
| Abnormality of the face | Uncommon - Between 30% and 50% cases |
| Microdontia | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with LRP6 gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Hypoplasia of the maxilla
- Micrognathia
- Taurodontia
- Agenesis of permanent teeth
- Gout
- Hypercholesterolemia
- Osteoporosis
- Hyperlipidemia
And 8 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to LRP6 gene
Here you will find a list of rare diseases related to the LRP6. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
CORONARY ARTERY DISEASE, AUTOSOMAL DOMINANT 2; ADCAD2
Most common symptoms of CORONARY ARTERY DISEASE, AUTOSOMAL DOMINANT 2; ADCAD2
- Hypertension
- Osteoporosis
- Diabetes mellitus
- Stroke
- Sudden cardiac death
More info about CORONARY ARTERY DISEASE, AUTOSOMAL DOMINANT 2; ADCAD2
TOOTH AGENESIS, SELECTIVE, 7; STHAG7
Most common symptoms of TOOTH AGENESIS, SELECTIVE, 7; STHAG7
- Oligodontia
- Agenesis of permanent teeth
- Taurodontia
More info about TOOTH AGENESIS, SELECTIVE, 7; STHAG7
SOURCES: OMIM
OLIGODONTIA
Alternate names
OLIGODONTIA Is also known as selective tooth agenesis
Description
Oligodontia is a rare developmental dental anomaly in humans characterized by the absence of six or more teeth.
Most common symptoms of OLIGODONTIA
- Micrognathia
- Hypoplasia of the maxilla
- Microdontia
- Abnormality of the face
- Oligodontia
More info about OLIGODONTIA
SOURCES: ORPHANET
Search interest in LRP6
Potential gene panels for LRP6 gene
Hypercholesterolemia, familial (NGS panel for 15 genes) Panel
Portugal.
By CGC Genetics Hypercholesterolemia, familial (NGS panel for 15 genes) that also includes the following genes: ABCG5 ABCG8 APTX PPP1R17 LDLRAP1 PCSK9 EPHX2 GHR ITIH4 LDLR
More info about this panel Portugal.
Oligodontia - Selective tooth agenesis Comprehensive panel Panel
United States.
By Connective Tissue Gene Tests Oligodontia - Selective tooth agenesis Comprehensive panel that also includes the following genes: WNT10B WNT10A EDA LRP6 LTBP3 MSX1 PAX9 AXIN2 PTH1R
More info about this panel United States.
Oligodontia - Selective tooth agenesis NGS panel Panel
United States.
By Connective Tissue Gene Tests Oligodontia - Selective tooth agenesis NGS panel that also includes the following genes: WNT10B WNT10A EDA LRP6 LTBP3 MSX1 PAX9 AXIN2 PTH1R
More info about this panel United States.
Oligodontia - Selective tooth agenesis Deletion / Duplication panel Panel
United States.
By Connective Tissue Gene Tests Oligodontia - Selective tooth agenesis Deletion / Duplication panel that also includes the following genes: WNT10B WNT10A EDA LRP6 LTBP3 MSX1 PAX9 AXIN2 PTH1R
More info about this panel United States.
Inherited Cardiovascular Diseases and Sudden Death Panel Panel
Spain.
By Health in Code Inherited Cardiovascular Diseases and Sudden Death Panel that also includes the following genes: MRPL3 RYR2 SCN10A SCN1B SCN2B SCN4B SCN5A BMPR1B BMPR2 SGCA
More info about this panel Spain.
Cardiovascular Diseases_General Panel Panel
Spain.
By Health in Code Cardiovascular Diseases_General Panel that also includes the following genes: RIT1 MRPL3 RRAS RYR1 RYR2 SAR1B BLK SCN10A SCN1B SCN2B
More info about this panel Spain.
Dyslipidemias / Early atherosclerosis Panel
Spain.
By Health in Code Dyslipidemias / Early atherosclerosis that also includes the following genes: RYR1 SAR1B BLK SLCO1B1 SLC22A8 SLC2A2 HNF1A HNF1B KLF11 WFS1
More info about this panel Spain.
qGenEx Craniofacial Anomalies Panel
Spain.
By Quantitative Genomic Medicine Laboratories, SL qGenEx Craniofacial Anomalies that also includes the following genes: RUNX2 SALL1 TSHZ1 BMP4 SEMA3E SF3B4 SH3BP2 SHH SIX1 SIX3
More info about this panel Spain.
Sudden Death Syndrome NGS Panel Panel
United States.
By Fulgent Genetics Fulgent Genetics Sudden Death Syndrome NGS Panel that also includes the following genes: RYR2 SCN1B SCN4B SCN5A SGCD SLC25A4 SNTA1 TAZ TCAP TGFB3
More info about this panel United States.
LRP6 Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the LRP6 gene.
More info about this panel United States.
Ectodermal Dysplasia Panel Panel
Finland.
By Blueprint Genetics Ectodermal Dysplasia Panel that also includes the following genes: RMRP BCS1L IFT122 WNT10A EDARADD TP63 MPLKIP CDH3 PORCN EVC2
More info about this panel Finland.
Tempus xO assay Panel
United States.
By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2
More info about this panel United States.
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