LIN28B gene related symptoms and diseases
All the information presented here about the LIN28B gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,ORPHANET,NCBIGENE,HGNC, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to LIN28B gene
Symptoms // Phenotype | % Cases |
---|---|
Ataxia | Very Common - Between 80% and 100% cases |
Spinal cord compression | Very Common - Between 80% and 100% cases |
Elevated urinary homovanillic acid | Very Common - Between 80% and 100% cases |
Elevated urinary catecholamines | Very Common - Between 80% and 100% cases |
Elevated urinary dopamine | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with LIN28B gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Abdominal mass
- Opsoclonus
- Adrenal calcification
- Ganglioneuroblastoma
- Horner syndrome
- Neoplasm of the nervous system
- Ganglioneuroma
- Paraganglioma
And 17 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to LIN28B gene
Here you will find a list of rare diseases related to the LIN28B. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
NEUROBLASTOMA
Description
Neuroblastoma is a malignant tumor of neural crest cells, the cells that give rise to the sympathetic nervous system, which is observed in children.
Most common symptoms of NEUROBLASTOMA
- Ataxia
- Neoplasm
- Failure to thrive
- Pain
- Anemia
More info about NEUROBLASTOMA
Search interest in LIN28B
Potential gene panels for LIN28B gene
LIN28B Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the LIN28B gene.
More info about this panelIf you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like EBF3 GTPBP3 TJP2 ATXN10 FH ARSE SLCO1B1