LCT gene related symptoms and diseases
All the information presented here about the LCT gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,HGNC,OMIM,ORPHANET, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to LCT gene
Symptoms // Phenotype | % Cases |
---|---|
Diarrhea | Very Common - Between 80% and 100% cases |
Carious teeth | Very Common - Between 80% and 100% cases |
Metabolic acidosis | Very Common - Between 80% and 100% cases |
Dehydration | Very Common - Between 80% and 100% cases |
Atherosclerosis | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with LCT gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Fructose intolerance
- Lactose intolerance
- Decreased small intestinal mucosa lactase activity
Rare diseases associated to LCT gene
Here you will find a list of rare diseases related to the LCT. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
CONGENITAL LACTASE DEFICIENCY
Alternate names
CONGENITAL LACTASE DEFICIENCY Is also known as disaccharide intolerance ii, alactasia, congenital
Description
Congenital lactase deficiency is a rare severe gastrointestinal disorder in newborns primarily reported in Finland and characterized clinically by watery diarrhea on feeding with breast-milk or lactose-containing formula.
Most common symptoms of CONGENITAL LACTASE DEFICIENCY
- Diarrhea
- Carious teeth
- Metabolic acidosis
- Dehydration
- Atherosclerosis
Search interest in LCT
Potential gene panels for LCT gene
LCT. Detection of the mutation c.4170T>A (p.Tyr1390Ter) by sequencing Panel
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the LCT gene.
More info about this panelLCT. Complete sequencing Panel
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the LCT gene.
More info about this panelCongenital Diarrhea Seq Analysis Panel
By Division of Genomic Diagnostics The Children's Hospital of Philadelphia Congenital Diarrhea Seq Analysis that also includes the following genes: SAR1B SI SKIV2L SLC5A1 SLC9A3 SPINT2 STX3 EPCAM NEUROG3 CFTR
More info about this panelCongenital Diarrhea Del/Dup Panel Panel
By Division of Genomic Diagnostics The Children's Hospital of Philadelphia Congenital Diarrhea Del/Dup Panel that also includes the following genes: SAR1B SI SKIV2L SLC5A1 SLC9A3 SPINT2 STX3 EPCAM NEUROG3 CFTR
More info about this panelCongenital Diarrhea Seq + Del/Dup Panel Panel
By Division of Genomic Diagnostics The Children's Hospital of Philadelphia Congenital Diarrhea Seq + Del/Dup Panel that also includes the following genes: SAR1B SI SKIV2L SLC5A1 SLC9A3 SPINT2 STX3 EPCAM NEUROG3 CFTR
More info about this panelCongenital lactase deficiency (sequence analysis of LCT gene) Panel
By CGC Genetics
This panel specifically test the LCT gene.
More info about this panelLactase deficiency, congenital Panel
By Centogene AG - the Rare Disease Company
This panel specifically test the LCT gene.
More info about this panelCongenital lactase deficiency Panel
By bio.logis Center for Human Genetics Diagnosticum
This panel specifically test the LCT gene.
More info about this panelLactose Intolerance, Adult Type (LCT) Panel
By MVZ Dortmund Dr. Eberhard & Partner
This panel specifically test the LCT gene.
More info about this panelLactase persistence: LCT gene -13910C/T polymorphism analysis Panel
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases
This panel specifically test the LCT gene.
More info about this panelLCT Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the LCT gene.
More info about this panelCholestasis Panel Panel
By Blueprint Genetics Cholestasis Panel that also includes the following genes: SLC25A13 SMPD1 SPINT2 EPCAM TJP2 UGT1A1 VPS33B NEUROG3 LMF1 NPC2
More info about this panelCongenital Diarrhea Panel Panel
By Blueprint Genetics Congenital Diarrhea Panel that also includes the following genes: SAR1B SI SKIV2L SLC10A2 SLC5A1 SLC9A3 SPINT2 STX3 EPCAM NEUROG3
More info about this panelComprehensive Metabolism Panel Panel
By Blueprint Genetics Comprehensive Metabolism Panel that also includes the following genes: BCS1L CNNM2 RYR1 CNNM4 SCN4A SEC23B SGSH SI SLC40A1 SLC12A3
More info about this panelCongenital Mono- and Disaccharide Disorders Panel Panel
By Blueprint Genetics Congenital Mono- and Disaccharide Disorders Panel that also includes the following genes: SI SLC2A1 SLC2A2 SLC5A1 GALE GALK1 GALT ALDOB LCT
More info about this panelLactase deficiency, congenital Panel
By Bioarray
This panel specifically test the LCT gene.
More info about this panelCongenital Lactase Deficiency , Sequencing LCT Gene Panel
By Reference Laboratory Genetics
This panel specifically test the LCT gene.
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