KRT9 gene related symptoms and diseases
All the information presented here about the KRT9 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,ORPHANET,HGNC,NCBIGENE, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to KRT9 gene
Symptoms // Phenotype | % Cases |
---|---|
Neoplasm | Very Common - Between 80% and 100% cases |
Clubbing | Very Common - Between 80% and 100% cases |
Palmoplantar erythema | Very Common - Between 80% and 100% cases |
Nonepidermolytic palmoplantar keratoderma | Very Common - Between 80% and 100% cases |
Palmoplantar blistering | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with KRT9 gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Congenital bullous ichthyosiform erythroderma
- Increased IgE level
- Verrucae
- Follicular hyperkeratosis
- Ovarian neoplasm
- Congenital ichthyosiform erythroderma
- Erythroderma
- Abnormality of the dentition
And 11 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to KRT9 gene
Here you will find a list of rare diseases related to the KRT9. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
EPIDERMOLYTIC PALMOPLANTAR KERATODERMA
Alternate names
EPIDERMOLYTIC PALMOPLANTAR KERATODERMA Is also known as eppk, keratosis palmaris et plantaris familiaris, diffuse erythrodermic palmoplantar keratoderma, vÖrner type, epidermolytic palmoplantar keratoderma of voerner, keratosis of greither, ppke, epidermolytic palmoplantar keratoderma of vÖrner, diffuse erythrodermic
Description
Palmoplantar keratoderma (PPK) is a common hereditary cutaneous disorder characterized by marked hyperkeratosis on the surface of palms and soles (Hennies et al., 1995). PPK has been classified into diffuse, focal, and punctate forms according to the pattern of hyperkeratosis on the palms and soles (Lucker et al., 1994). Diffuse PPK develops at birth or shortly thereafter and involves the entire palm and sole with a sharp cutoff at an erythematous border; there are no lesions outside the volar skin, and, in particular, no follicular or oral lesions. In contrast, focal PPK is a late-onset form in which focal hyperkeratotic lesions develop in response to mechanical trauma; an important distinguishing feature is the presence of lesions at other body sites, e.g., oral and follicular hyperkeratosis (Stevens et al., 1996). Palmoplantar keratodermas can be further subdivided histologically into epidermolytic and nonepidermolytic PPK (Risk et al., 1994).
Most common symptoms of EPIDERMOLYTIC PALMOPLANTAR KERATODERMA
- Neoplasm
- Abnormality of the dentition
- Clinodactyly
- Hyperhidrosis
- Hyperkeratosis
More info about EPIDERMOLYTIC PALMOPLANTAR KERATODERMA
Search interest in KRT9
Potential gene panels for KRT9 gene
KRT9 Panel
By Institute for Human Genetics University Clinic Freiburg
This panel specifically test the KRT9 gene.
More info about this panelKRT9. Complete sequencing Panel
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the KRT9 gene.
More info about this panelPalmoplantar keratoderma, epidermolytic (sequence analysis of KRT9 gene) Panel
By CGC Genetics
This panel specifically test the KRT9 gene.
More info about this panelCongenital Ichthyosis and Related Disorders Sequencing Panel with CNV Detection Panel
By PreventionGenetics PreventionGenetics Congenital Ichthyosis and Related Disorders Sequencing Panel with CNV Detection that also includes the following genes: SLC27A4 ST14 TGM1 ALOXE3 ABCA12 CLDN1 POMP PNPLA1 ABHD5 LIPN
More info about this panelPalmoplantar Keratoderma, Epidermolytic via KRT9 Gene Sequencing with CNV Detection Panel
By PreventionGenetics PreventionGenetics
This panel specifically test the KRT9 gene.
More info about this panelEpidermolytic palmoplantar keratoderma Panel
By Centogene AG - the Rare Disease Company
This panel specifically test the KRT9 gene.
More info about this panelIchthyoses and related disorders of cornification Panel Panel
By CeGaT GmbH Ichthyoses and related disorders of cornification Panel that also includes the following genes: SLC27A4 SNAP29 ST14 STS TAT TGM1 TGM5 VPS33B ATP2C1 NSDHL
More info about this panelKRT9 Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the KRT9 gene.
More info about this panelIchthyosis Panel Panel
By Blueprint Genetics Ichthyosis Panel that also includes the following genes: SLC27A4 STS TGM1 ALOXE3 ABCA12 MBTPS2 SPINK5 MPLKIP CDSN SUMF1
More info about this panelPalmoplantar Keratoderma Panel Panel
By Blueprint Genetics Palmoplantar Keratoderma Panel that also includes the following genes: WNT10A SERPINB7 MBTPS2 TRPV3 SLURP1 KRT6C CTSC AAGAB DSG1 DSP
More info about this panelEpidermolytic palmoplantar keratoderma Panel
By Bioarray
This panel specifically test the KRT9 gene.
More info about this panelPALMOPLANTAR KERATODERMA, EPIDERMOLYTIC Panel
By Laboratorio de Genetica Clinica SL PALMOPLANTAR KERATODERMA, EPIDERMOLYTIC that also includes the following genes: KRT1 KRT9
More info about this panelEpidermolytic Palmoplantar Keratoderma, Sequencing KRT9 Gene Panel
By Reference Laboratory Genetics
This panel specifically test the KRT9 gene.
More info about this panelEpidermolytic Palmoplantar Keratoderma, Sequencing Exons (1,6) KRT9 Gene Panel
By Reference Laboratory Genetics
This panel specifically test the KRT9 gene.
More info about this panelCongenital Ichthyosis and related disorders , Panel Massive Sequencing (NGS) 33 Genes Panel
By Reference Laboratory Genetics Congenital Ichthyosis and related disorders , Panel Massive Sequencing (NGS) 33 Genes that also includes the following genes: SLC27A4 SNAP29 ST14 STS TGM1 TGM5 ALOXE3 ABCA12 SPINK5 MPLKIP
More info about this panelPalmoplantar Keratoderma and Related Disorders , Panel Massive Sequencing (NGS) 6 Genes Panel
By Reference Laboratory Genetics Palmoplantar Keratoderma and Related Disorders , Panel Massive Sequencing (NGS) 6 Genes that also includes the following genes: TRPV3 AQP5 KRT1 KRT10 KRT16 KRT9
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