KRT85 gene related symptoms and diseases
All the information presented here about the KRT85 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,OMIM,NCBIGENE,HGNC, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to KRT85 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Alopecia | Very Common - Between 80% and 100% cases |
| Sparse body hair | Very Common - Between 80% and 100% cases |
| Congenital onychodystrophy | Very Common - Between 80% and 100% cases |
| Hair-nail ectodermal dysplasia | Very Common - Between 80% and 100% cases |
| Hidrotic ectodermal dysplasia | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with KRT85 gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Alopecia totalis
- Onycholysis
- Pili torti
- Absent eyelashes
- Absent eyebrow
- Hyperhidrosis
- Brittle hair
- Palmoplantar hyperkeratosis
And 7 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to KRT85 gene
Here you will find a list of rare diseases related to the KRT85. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
PURE HAIR AND NAIL ECTODERMAL DYSPLASIA
Alternate names
PURE HAIR AND NAIL ECTODERMAL DYSPLASIA Is also known as hair-nail ectodermal dysplasia, hned, phned, ectodermal dysplasia, 'pure' hair/nail type
Description
Pure hair and nail ectodermal dysplasia is characterised by the association of onychodystrophy and severe hypotrichosis, which is mainly limited to the scalp but may also affect the eyelashes and eyebrows. Less than 20 cases have been reported so far. The mode of transmission is autosomal dominant.
Most common symptoms of PURE HAIR AND NAIL ECTODERMAL DYSPLASIA
- Alopecia
- Hyperhidrosis
- Hyperkeratosis
- Sparse hair
- Papule
More info about PURE HAIR AND NAIL ECTODERMAL DYSPLASIA
Search interest in KRT85
Potential gene panels for KRT85 gene
Ectodermal dysplasia (NGS panel for 8 genes) Panel
Portugal.
By CGC Genetics Ectodermal dysplasia (NGS panel for 8 genes) that also includes the following genes: EDARADD KRT74 EDAR EDA GJB6 HOXC13 KRT85 MSX1
More info about this panel Portugal.
Ectodermal dysplasia (NGS panel for 8 genes) Panel
Portugal.
By CGC Genetics Ectodermal dysplasia (NGS panel for 8 genes) that also includes the following genes: EDARADD KRT74 EDAR EDA GJB6 HOXC13 KRT85 MSX1
More info about this panel Portugal.
Ectodermal Dysplasia Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Ectodermal Dysplasia Sequencing Panel with CNV Detection that also includes the following genes: WNT10A EDARADD EDAR EDA KRT85 NECTIN1
More info about this panel United States.
Ectodermal Dysplasia via KRT85 Gene Sequencing with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics
This panel specifically test the KRT85 gene.
More info about this panel United States.
Ectodermal dysplasia Comprehensive panel Panel
United States.
By Connective Tissue Gene Tests Ectodermal dysplasia Comprehensive panel that also includes the following genes: EDARADD KDF1 KRT74 EDAR EDA GJB6 HOXC13 KRT85 MSX1
More info about this panel United States.
Ectodermal dysplasia Deletion / Duplication panel Panel
United States.
By Connective Tissue Gene Tests Ectodermal dysplasia Deletion / Duplication panel that also includes the following genes: EDARADD KDF1 KRT74 EDAR EDA GJB6 HOXC13 KRT85 MSX1
More info about this panel United States.
Ectodermal dysplasia NGS panel Panel
United States.
By Connective Tissue Gene Tests Ectodermal dysplasia NGS panel that also includes the following genes: EDARADD KDF1 KRT74 EDAR EDA GJB6 HOXC13 KRT85 MSX1
More info about this panel United States.
Ectodermal dysplasia type 4, hair/nail type Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the KRT85 gene.
More info about this panel Germany.
Ectodermal dysplasia (including hypotrichosis and hypoplastic hair) Panel Panel
Germany.
By CeGaT GmbH Ectodermal dysplasia (including hypotrichosis and hypoplastic hair) Panel that also includes the following genes: BCS1L SNRPE SOX18 ST14 TRPS1 IFT122 WNT10A EDARADD SHOC2 LPAR6
More info about this panel Germany.
KRT85 Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the KRT85 gene.
More info about this panel United States.
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