IRGM gene related symptoms and diseases
All the information presented here about the IRGM gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,OMIM,HGNC, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to IRGM gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Inflammation of the large intestine | Uncommon - Between 30% and 50% cases |
| Pain | Uncommon - Between 30% and 50% cases |
| Fever | Uncommon - Between 30% and 50% cases |
| Fatigue | Uncommon - Between 30% and 50% cases |
| Immunodeficiency | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with IRGM gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Weight loss
- Cough
- Chest pain
- Hemoptysis
- Night sweats
Rare diseases associated to IRGM gene
Here you will find a list of rare diseases related to the IRGM. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
INFLAMMATORY BOWEL DISEASE (CROHN DISEASE) 19; IBD19
Most common symptoms of INFLAMMATORY BOWEL DISEASE (CROHN DISEASE) 19; IBD19
- Inflammation of the large intestine
More info about INFLAMMATORY BOWEL DISEASE (CROHN DISEASE) 19; IBD19
MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO
Description
Mycobacterium tuberculosis latently infects approximately one-third of humanity and is comparable only to human immunodeficiency virus (HIV; see {609423}) as a leading infectious cause of mortality worldwide. Obstacles for controlling TB infection include lengthy treatment regimens of 6 to 9 months, drug resistance, lack of a highly efficacious vaccine, and incomplete understanding of the factors that control infectivity and disease progression. Although only 10% of individuals infected with M. tuberculosis develop active disease, the immune responses associated with TB susceptibility or resistance are not known. In addition, it is not known why some individuals have disseminated TB that spreads to the meninges and central nervous system, while most people have localized disease in the lungs. A number of studies suggest that host genetic factors influence susceptibility and resistance to TB (review by Berrington and Hawn, 2007).
Most common symptoms of MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO
- Pain
- Fever
- Fatigue
- Immunodeficiency
- Weight loss
More info about MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO
Search interest in IRGM
Potential gene panels for IRGM gene
IRGM Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the IRGM gene.
More info about this panel United States.
Inflammatory Bowel Disease (IBD) and Related Disorders , Panel Massive Sequencing (NGS) 46 Genes Panel
Spain.
By Reference Laboratory Genetics Inflammatory Bowel Disease (IBD) and Related Disorders , Panel Massive Sequencing (NGS) 46 Genes that also includes the following genes: SH2D1A STXBP2 TERC TERT TGFB1 TINF2 CD40LG WAS WIPF1 CARD9
More info about this panel Spain.
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