HTR2A gene related symptoms and diseases
All the information presented here about the HTR2A gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,NCBIGENE,HGNC, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to HTR2A gene
Symptoms // Phenotype | % Cases |
---|---|
Depressivity | Very Common - Between 80% and 100% cases |
Behavioral abnormality | Common - Between 50% and 80% cases |
Anxiety | Common - Between 50% and 80% cases |
Bipolar affective disorder | Common - Between 50% and 80% cases |
Personality disorder | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with HTR2A gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Mania
- Schizophrenia
- Alcoholism
Rarely - Less than 30% cases
- Neurofibrillary tangles
- Psychosis
- Dyskinesia
- Auditory hallucinations
- Chorea
And 32 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to HTR2A gene
Here you will find a list of rare diseases related to the HTR2A. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
OBSESSIVE-COMPULSIVE DISORDER; OCD
Description
Obsessive-compulsive disorder (OCD) is characterized by recurring obsessions and/or compulsions and has been estimated to affect nearly 5 million people in the United States (Karno et al., 1988). Evidence for a strong genetic component in OCD comes from twin studies, family genetics studies, and segregation analyses, as reviewed by Alsobrook et al. (2002).Zhang et al. (2002) suggested that hoarding is likely to be an evolutionarily conserved trait that, in times of adversity, was associated with increased survival and reproductive fitness. However, extreme forms of this trait are associated with marked disability and poor response to treatment (Black et al., 1998; Mataix-Cols et al., 1999).
Most common symptoms of OBSESSIVE-COMPULSIVE DISORDER; OCD
- Depressivity
- Anxiety
- Obsessive-compulsive behavior
- Tics
- Collectionism
More info about OBSESSIVE-COMPULSIVE DISORDER; OCD
MAJOR DEPRESSIVE DISORDER; MDD
Alternate names
MAJOR DEPRESSIVE DISORDER; MDD Is also known as unipolar depression
Most common symptoms of MAJOR DEPRESSIVE DISORDER; MDD
- Neoplasm
- Behavioral abnormality
- Depressivity
- Anxiety
- Abnormality of the liver
More info about MAJOR DEPRESSIVE DISORDER; MDD
SOURCES: OMIM
ALCOHOL DEPENDENCE
Alternate names
ALCOHOL DEPENDENCE Is also known as alcoholism
Description
a disorder characterized by a pathological pattern of alcohol use that causes a serious impairment in social or occupational functioning.
Most common symptoms of ALCOHOL DEPENDENCE
- Seizures
- Behavioral abnormality
- Depressivity
- Hyperactivity
- Abnormality of the nervous system
More info about ALCOHOL DEPENDENCE
SOURCES: OMIM
SCHIZOPHRENIA; SCZD
Alternate names
SCHIZOPHRENIA; SCZD Is also known as schizophrenia with or without an affective disorder
Description
Schizophrenia is a psychosis, a disorder of thought and sense of self. Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. There is no characteristic pathology, such as neurofibrillary tangles in Alzheimer disease (OMIM ). Schizophrenia is a common disorder with a lifetime prevalence of approximately 1%. It is highly heritable but the genetics are complex. This may not be a single entity.Schizophrenia and bipolar disorder (see {125480}) are generally considered to be separate entities, but patients who exhibit multiple symptoms of both disorders are often given the hybrid diagnosis schizoaffective disorder (Blacker and Tsuang, 1992).
Most common symptoms of SCHIZOPHRENIA; SCZD
- Intellectual disability
- Microcephaly
- Behavioral abnormality
- Depressivity
- Dementia
More info about SCHIZOPHRENIA; SCZD
SOURCES: OMIM
Search interest in HTR2A
Potential gene panels for HTR2A gene
Serotonin Metabolism Deficiency NGS Panel Panel
By Fulgent Genetics Fulgent Genetics Serotonin Metabolism Deficiency NGS Panel that also includes the following genes: SLC6A4 TPH1 AANAT TPH2 HTR3C HTR3E DDC HTR1A HTR1B HTR2A
More info about this panelHTR2A Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the HTR2A gene.
More info about this panelHTR2A Panel
By Genelex
This panel specifically test the HTR2A gene.
More info about this panelYouScript Psychotropic Panel
By Genelex YouScript Psychotropic that also includes the following genes: SLC6A4 CYP2C19 CYP2C9 CYP2D6 CYP3A4 CYP3A5 HTR2A
More info about this panelGeneSight Psychotropic Panel
By Assurex Health, Inc. GeneSight Psychotropic that also includes the following genes: SLC6A4 UGT1A4 UGT2B15 CYP2B6 CYP2C19 CYP2C9 CYP2D6 CYP3A4 HLA-A HTR2A
More info about this panelComprehensive Pharmacogenomics (PGX) Panel Panel
By ApolloGen, Inc. Comprehensive Pharmacogenomics (PGX) Panel that also includes the following genes: SLCO1B1 VKORC1 CYP2C19 CYP2C9 CYP2D6 CYP3A4 CYP3A5 F5 HTR2A MTHFR
More info about this panelOneOme RightMed comprehensive test Panel
By OneOme OneOme RightMed comprehensive test that also includes the following genes: SLCO1B1 SLC6A4 TPMT UGT1A1 IFNL3 NUDT15 VKORC1 CYP2B6 CYP2C18 CYP2C19
More info about this panelCitalopram response Panel
By Xcode Life Xcode Life Citalopram response that also includes the following genes: SLC6A4 CYP2C19 HTR2A
More info about this panelTempus xO assay Panel
By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2
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