1. Mendelian
  2. Rare Disease Genes
  3. HLA-DRA

HLA-DRA gene related symptoms and diseases

All the information presented here about the HLA-DRA gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,OMIM,ORPHANET,HGNC, Mendelian Rare Disease Search Engine.

Table of contents:

Top 5 symptoms and clinical features associated to HLA-DRA gene

Symptoms // Phenotype % Cases
Alopecia Very Common - Between 80% and 100% cases
Scarring Very Common - Between 80% and 100% cases
Pruritus Very Common - Between 80% and 100% cases
Hypotrichosis Very Common - Between 80% and 100% cases
Sparse scalp hair Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with HLA-DRA gene alterations may also develop some of the following symptoms and phenotypes:

  • Commonly - More than 50% cases

  • Sparse axillary hair
  • Sparse pubic hair
  • Lichenification
  • Scarring alopecia of scalp
  • Perifollicular hyperkeratosis

Rare diseases associated to HLA-DRA gene

Here you will find a list of rare diseases related to the HLA-DRA. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


GRAHAM LITTLE-PICCARDI-LASSUEUR SYNDROME

Alternate names

GRAHAM LITTLE-PICCARDI-LASSUEUR SYNDROME Is also known as graham little syndrome, piccardi-lassueur-little syndrome

Description

Graham Little-Piccardi-Lassueur syndrome is a variant of lichen planopilaris (see this term) characterized by the clinical triad of progressive cicatricial (scarring) alopecia of the scalp, follicular keratotic papules on glabrous skin, and variable alopecia of the axillae and groin.

Most common symptoms of GRAHAM LITTLE-PICCARDI-LASSUEUR SYNDROME

  • Alopecia
  • Scarring
  • Pruritus
  • Hypotrichosis
  • Sparse scalp hair


More info about GRAHAM LITTLE-PICCARDI-LASSUEUR SYNDROME

SOURCES: ORPHANET


Potential gene panels for HLA-DRA gene

HLA-DRA Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the HLA-DRA gene.

More info about this panel
United States.

Tempus xT assay Panel

United States.

By Tempus Labs, Inc. Tempus xT assay that also includes the following genes: BCL6 RIT1 BCL7A BCR ROS1 RPL5 RPS15 RPS6KB1 RUNX1 RXRA

More info about this panel
United States.

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