1. Mendelian
  2. Rare Disease Genes
  3. FOS

FOS gene related symptoms and diseases

All the information presented here about the FOS gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,ORPHANET,OMIM,HGNC, Mendelian Rare Disease Search Engine.

Table of contents:

Top 5 symptoms and clinical features associated to FOS gene

Symptoms // Phenotype % Cases
Intellectual disability Very Common - Between 80% and 100% cases
Atherosclerosis Very Common - Between 80% and 100% cases
Large hands Very Common - Between 80% and 100% cases
Lipodystrophy Very Common - Between 80% and 100% cases
Hyperinsulinemia Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with FOS gene alterations may also develop some of the following symptoms and phenotypes:

  • Commonly - More than 50% cases

  • Precocious puberty
  • Prominent supraorbital ridges
  • Pyloric stenosis
  • Polycystic ovaries
  • Acanthosis nigricans
  • Lipoatrophy
  • Pancreatitis
  • Accelerated skeletal maturation

And 72 more phenotypes, you can get all of them using our tools for rare diseases.

Rare diseases associated to FOS gene

Here you will find a list of rare diseases related to the FOS. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


BERARDINELLI-SEIP CONGENITAL LIPODYSTROPHY

Alternate names

BERARDINELLI-SEIP CONGENITAL LIPODYSTROPHY Is also known as lipoatrophic diabetes, generalized congenital lipodystrophy, gcl, brunzell syndrome, bscl, beradinelli-seip syndrome

Description

Berardinelli-Seip congenital lipodystrophy (BSCL) is characterized by the association of lipoatrophy, hypertriglyceridemia, hepatomegaly and acromegaloid features. BSCL belongs to the group of extreme insulin resistance syndromes, which also includes leprechaunism, Rabson-Mendenhall syndrome, acquired generalized lipodystrophy, and types A and B insulin resistance (see these terms).

Most common symptoms of BERARDINELLI-SEIP CONGENITAL LIPODYSTROPHY

  • Intellectual disability
  • Global developmental delay
  • Short stature
  • Scoliosis
  • Growth delay


More info about BERARDINELLI-SEIP CONGENITAL LIPODYSTROPHY

SOURCES: ORPHANET


Potential gene panels for FOS gene

FOS Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the FOS gene.

More info about this panel
United States.

LIPODYSTROPHY, FAMILIAL PARTIAL AND CONGENITAL NGS PANEL Panel

Spain.

By Laboratorio de Genetica Clinica SL LIPODYSTROPHY, FAMILIAL PARTIAL AND CONGENITAL NGS PANEL that also includes the following genes: ZMPSTE24 CAV1 BSCL2 TBC1D4 MLIP CIDEC AGPAT2 FOS AKT2 LIPE

More info about this panel
Spain.

Tempus xO assay Panel

United States.

By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2

More info about this panel
United States.

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