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  2. Rare Disease Genes
  3. FLG2

FLG2 gene related symptoms and diseases

All the information presented here about the FLG2 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,HGNC,OMIM,ORPHANET, Mendelian Rare Disease Search Engine.

Table of contents:

Top 5 symptoms and clinical features associated to FLG2 gene

Symptoms // Phenotype % Cases
Hyperkeratosis Uncommon - Between 30% and 50% cases
Scaling skin Uncommon - Between 30% and 50% cases
Generalized ichthyosis Uncommon - Between 30% and 50% cases
Orthokeratosis Uncommon - Between 30% and 50% cases
Skin erosion Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with FLG2 gene alterations may also develop some of the following symptoms and phenotypes:

  • Not very common - Between 30% and 50% cases

  • Allergy
  • Parakeratosis
  • Rhinitis
  • High hypermetropia
  • Macule
  • Hyperpigmentation of the skin
  • Erythema
  • Eczema

And 8 more phenotypes, you can get all of them using our tools for rare diseases.

Rare diseases associated to FLG2 gene

Here you will find a list of rare diseases related to the FLG2. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


PEELING SKIN SYNDROME TYPE A

Alternate names

PEELING SKIN SYNDROME TYPE A Is also known as generalized peeling skin syndrome type a, non-inflammatory peeling skin syndrome type a, pss type a, non-inflammatory generalized peeling skin syndrome type a., generalized deciduous skin type a

Description

Peeling skin syndrome (PSS) type A is a non inflammatory form of generalized PSS (see this term), a type of ichthyosis (see this term), characterized by generalized white scaling and superficial painless peeling of the skin.


More info about PEELING SKIN SYNDROME TYPE A

SOURCES: ORPHANET

ACRAL PEELING SKIN SYNDROME

Alternate names

ACRAL PEELING SKIN SYNDROME Is also known as localized pss, acral pss, localized deciduous skin, acral deciduous skin

Description

Acral peeling skin syndrome (PSS) is a form of PSS (see this term) characterized by superficial peeling of the skin predominantly affecting the dorsa of the hands and feet.

Most common symptoms of ACRAL PEELING SKIN SYNDROME

  • Hyperkeratosis
  • Erythema
  • Scarring
  • Papule
  • Pruritus


More info about ACRAL PEELING SKIN SYNDROME

SOURCES: OMIM ORPHANET


Potential gene panels for FLG2 gene

Peeling skin syndrome NGS panel Panel

United States.

By Connective Tissue Gene Tests Peeling skin syndrome NGS panel that also includes the following genes: TGM5 CAST CHST8 CDSN CSTA FLG2 SERPINB8

More info about this panel
United States.

Peeling skin syndrome Comprehensive panel Panel

United States.

By Connective Tissue Gene Tests Peeling skin syndrome Comprehensive panel that also includes the following genes: TGM5 CAST CHST8 CDSN CSTA FLG2 SERPINB8

More info about this panel
United States.

Peeling skin syndrome Deletion / Duplication panel Panel

United States.

By Connective Tissue Gene Tests Peeling skin syndrome Deletion / Duplication panel that also includes the following genes: TGM5 CAST CHST8 CDSN CSTA FLG2 SERPINB8

More info about this panel
United States.

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