FGG gene related symptoms and diseases
All the information presented here about the FGG gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,ORPHANET,NCBIGENE,HGNC, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to FGG gene
Symptoms // Phenotype | % Cases |
---|---|
Abnormal bleeding | Common - Between 50% and 80% cases |
Epistaxis | Common - Between 50% and 80% cases |
Gingival bleeding | Common - Between 50% and 80% cases |
Gastrointestinal hemorrhage | Uncommon - Between 30% and 50% cases |
Menometrorrhagia | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with FGG gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Hypofibrinogenemia
- Dysfibrinogenemia
Rarely - Less than 30% cases
- Venous thrombosis
- Spontaneous abortion
- Cerebral hemorrhage
- Joint swelling
- Abnormality of the liver
- Intracranial hemorrhage
And 1 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to FGG gene
Here you will find a list of rare diseases related to the FGG. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
FAMILIAL DYSFIBRINOGENEMIA
Description
Familial dysfibrinogenemia is a coagulation disorder characterized by a bleeding tendency due to a functional anomaly of circulating fibrinogen.
Most common symptoms of FAMILIAL DYSFIBRINOGENEMIA
- Abnormal bleeding
- Gastrointestinal hemorrhage
- Epistaxis
- Venous thrombosis
- Gingival bleeding
More info about FAMILIAL DYSFIBRINOGENEMIA
SOURCES: ORPHANET
FAMILIAL AFIBRINOGENEMIA
Description
Familial afibrinogenemia is a coagulation disorder characterized by bleeding symptoms due to a complete absence of circulating fibrinogen.
Most common symptoms of FAMILIAL AFIBRINOGENEMIA
- Abnormal bleeding
- Epistaxis
- Spontaneous abortion
- Cerebral hemorrhage
- Joint swelling
More info about FAMILIAL AFIBRINOGENEMIA
SOURCES: ORPHANET
FAMILIAL HYPODYSFIBRINOGENEMIA
FAMILIAL HYPOFIBRINOGENEMIA
Description
Familial hypofibrinogenemia is a coagulation disorder characterized by mild bleeding symptoms following trauma or surgery due to a reduced plasma fibrinogen concentration.
Most common symptoms of FAMILIAL HYPOFIBRINOGENEMIA
- Abnormal bleeding
- Gastrointestinal hemorrhage
- Epistaxis
- Gingival bleeding
- Hypofibrinogenemia
More info about FAMILIAL HYPOFIBRINOGENEMIA
AFIBRINOGENEMIA, CONGENITAL
Description
Inherited disorders of fibrinogen affect either the quantity (afibrinogenemia and hypofibrinogenemia; {202400}) or the quality (dysfibrinogenemia ) of the circulating fibrinogen or both (hypodysfibrinogenemia; see {616004}). Afibrinogenemia is characterized by the complete absence of immunoreactive fibrinogen. Bleeding due to afibrinogenemia usually manifests in the neonatal period, with 85% of cases presenting umbilical cord bleeding, but a later age of onst is not unusual. Bleeding may occur in the skin, gastrointestinal tract, genitourinary tract, or the central nervous system, with intracranial hemorrhage being reported as the major cause of death. Patients are susceptible to spontaneous rupture of the spleen. Menstruating women may experience menometrorrhagia. First-trimester abortion is common. Both arterial and venous thromboembolic complications have been reported (summary by de Moerloose and Neerman-Arbez, 2009).Hypofibrinogenemia is characterized by reduced amounts of immunoreactive fibrinogen. Patients are often heterozygous carriers of afibrinogenemia mutations and are usually asymptomatic. However, they may bleed when exposed to trauma or if they have a second associated hemostatic abnormality. Women may experience miscarriages. Liver disease occurs in rare cases (summary by de Moerloose and Neerman-Arbez, 2009).
Most common symptoms of AFIBRINOGENEMIA, CONGENITAL
- Abnormality of the liver
- Abnormal bleeding
- Intracranial hemorrhage
- Menometrorrhagia
- Hypofibrinogenemia
More info about AFIBRINOGENEMIA, CONGENITAL
SOURCES: OMIM
Search interest in FGG
Potential gene panels for FGG gene
Platelet Disorders Panel
By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University Platelet Disorders that also includes the following genes: RUNX1 STIM1 TBXA2R TBXAS1 USF1 VPS33B VWF WAS GP6 HPS3
More info about this panelCongenital fibrinogen deficiency Panel
By Institute of Human Genetics Uniklinik RWTH Aachen Congenital fibrinogen deficiency that also includes the following genes: FGA FGB FGG
More info about this panelFGG. Complete sequencing Panel
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the FGG gene.
More info about this panelAfibrinogenemia, congenital (sequence analysis of FGG gene) Panel
By CGC Genetics
This panel specifically test the FGG gene.
More info about this panelCongenital dysfibrinogenemia (sequence analysis of FGG gene) Panel
By CGC Genetics
This panel specifically test the FGG gene.
More info about this panelCongenital dysfibrinogenemia (sequence analysis of FGG gene) Panel
By CGC Genetics
This panel specifically test the FGG gene.
More info about this panelCongenital Fibrinogen Deficiency Sequencing Panel with CNV Detection Panel
By PreventionGenetics PreventionGenetics Congenital Fibrinogen Deficiency Sequencing Panel with CNV Detection that also includes the following genes: FGA FGB FGG
More info about this panelBleeding Disorders Sequencing Panel with CNV Detection Panel
By PreventionGenetics PreventionGenetics Bleeding Disorders Sequencing Panel with CNV Detection that also includes the following genes: RUNX1 TBXA2R TBXAS1 VWF WAS ADAMTS13 ABCG5 ABCG8 GP6 HPS3
More info about this panelCoagulation Factor Deficiency Sequencing Panel with CNV Detection Panel
By PreventionGenetics PreventionGenetics Coagulation Factor Deficiency Sequencing Panel with CNV Detection that also includes the following genes: VWF MCFD2 VKORC1 F10 F11 F12 F13A1 F13B F2 F5
More info about this panelCongenital Fibrinogen Deficiency via FGG Gene Sequencing with CNV Detection Panel
By PreventionGenetics PreventionGenetics
This panel specifically test the FGG gene.
More info about this panelCentoICU platinum plus Panel
By Centogene AG - the Rare Disease Company CentoICU platinum plus that also includes the following genes: RMRP BCS1L BDNF RPS19 RPS6KA3 SALL1 SCN1A SCN2A SFTPB SFTPC
More info about this panelNew Born testing (CentoICU) Panel
By Centogene AG - the Rare Disease Company New Born testing (CentoICU) that also includes the following genes: RMRP BCS1L BDNF RPS19 RPS6KA3 SALL1 SCN1A SCN2A SFTPB SFTPC
More info about this panelAfibrinogenemia panel Panel
By Centogene AG - the Rare Disease Company Afibrinogenemia panel that also includes the following genes: FGA FGB FGG
More info about this panelFibrinogen gene analysis (FGA, FGB & FGG) Panel
By Molecular Haemostasis & Thrombosis GSTS Pathology - Guy's and St. Thomas' NHS Foundation Trust Fibrinogen gene analysis (FGA, FGB & FGG) that also includes the following genes: FGA FGB FGG
More info about this panelaCGH Deletion/Duplication Analysis Panel
By BloodCenter of Wisconsin Diagnostic Laboratories BloodCenter of Wisconsin, part of Versiti aCGH Deletion/Duplication Analysis that also includes the following genes: CFB RUNX1 STXBP2 TBXA2R THBD VWF WAS C3 C4BPA C4BPB
More info about this panelAfibrinogenemia, congenital Panel
By Praxis fuer Humangenetik Wien
This panel specifically test the FGG gene.
More info about this panelDysfibrinogenemia Panel
By Praxis fuer Humangenetik Wien
This panel specifically test the FGG gene.
More info about this panelAfibrinogenemia, congenital Panel
By MedGene
This panel specifically test the FGG gene.
More info about this panelDysfibrinogenemia Panel
By MedGene
This panel specifically test the FGG gene.
More info about this panelFGG Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the FGG gene.
More info about this panelBleeding Disorder/Coagulopathy Panel Panel
By Blueprint Genetics Bleeding Disorder/Coagulopathy Panel that also includes the following genes: RUNX1 SRC TBXA2R THBD VWF WAS ADAMTS13 ABCG5 ABCG8 HPS3
More info about this panelCoagulation Factor Deficiency Panel Panel
By Blueprint Genetics Coagulation Factor Deficiency Panel that also includes the following genes: VWF VKORC1 F10 F11 F12 F13A1 F2 F5 F7 F8
More info about this panelComprehensive Hematology Panel Panel
By Blueprint Genetics Comprehensive Hematology Panel that also includes the following genes: RHAG RIT1 RPL11 RPL15 RPL35A RPL5 RPS10 RPS19 RPS24 RPS26
More info about this panelAfibrinogenemia, congenital Panel
By Bioarray
This panel specifically test the FGG gene.
More info about this panelAFIBRINOGENEMIA – DYSFIBRINOGENEMIA – HYPOFIBRINOGENEMIA Panel
By Laboratorio de Genetica Clinica SL AFIBRINOGENEMIA – DYSFIBRINOGENEMIA – HYPOFIBRINOGENEMIA that also includes the following genes: FGA FGB FGG
More info about this panelBleeding Disorders , Panel Massive Sequencing (NGS) 23 Genes Panel
By Reference Laboratory Genetics Bleeding Disorders , Panel Massive Sequencing (NGS) 23 Genes that also includes the following genes: VWF ADAMTS13 MCFD2 F10 F11 F12 F13A1 F2 F5 F7
More info about this panelCongenital Fibrinogen Disorders , Panel Massive Sequencing (NGS) FGA, FGB, FGG Genes Panel
By Reference Laboratory Genetics Congenital Fibrinogen Disorders , Panel Massive Sequencing (NGS) FGA, FGB, FGG Genes that also includes the following genes: FGA FGB FGG
More info about this panelAfibrinogenemia, congenital Panel
By Labor Dr. Wisplinghoff Afibrinogenemia, congenital that also includes the following genes: FGA FGB FGG
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