FGF2 gene related symptoms and diseases
All the information presented here about the FGF2 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,NCBIGENE,OMIM, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to FGF2 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Flexion contracture | Very Common - Between 80% and 100% cases |
| Narrow mouth | Very Common - Between 80% and 100% cases |
| Trismus | Very Common - Between 80% and 100% cases |
| Cheilitis | Very Common - Between 80% and 100% cases |
| Abnormality of the pharynx | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with FGF2 gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Abnormal oral cavity morphology
- Oropharyngeal squamous cell carcinoma
Rare diseases associated to FGF2 gene
Here you will find a list of rare diseases related to the FGF2. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
ORAL SUBMUCOUS FIBROSIS
Alternate names
ORAL SUBMUCOUS FIBROSIS Is also known as osmf
Description
Oral submucous fibrosis (OSMF) is a chronic, progressive disease that alters the fibroelasticity of the oral submucosa, prevalent in India and Southeast Asia but rare elsewhere, and characterized by burning and pain in the oral cavity, loss of gustatory sensation, the presence of blanched fibrous bands and stiffening of the oral mucosa and oro-pharynx (leading to trismus and a progressive reduction in mouth opening) and an increased risk of developing oral squamous cell cancer (3-19%). It is usually associated with the chewing of the areca nut (an ingredient in betel quid) but the exact etiology is unknown and there is currently no effective treatment.
Most common symptoms of ORAL SUBMUCOUS FIBROSIS
- Flexion contracture
- Narrow mouth
- Trismus
- Cheilitis
- Abnormality of the pharynx
Search interest in FGF2
Potential gene panels for FGF2 gene
FGF2 Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the FGF2 gene.
More info about this panelOnco microarray for CLL Panel
By Pittsburgh Cytogenetics Laboratory University of Pittsburgh Medical Center Onco microarray for CLL that also includes the following genes: BCL6 TP53 BCL11A CCND1 FGF2 AKT1 ALK IGH ITK MYB
More info about this panelTempus xT assay Panel
By Tempus Labs, Inc. Tempus xT assay that also includes the following genes: BCL6 RIT1 BCL7A BCR ROS1 RPL5 RPS15 RPS6KB1 RUNX1 RXRA
More info about this panelTempus xO assay Panel
By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2
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