FGF10 gene related symptoms and diseases
All the information presented here about the FGF10 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,HGNC,ORPHANET,NCBIGENE, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to FGF10 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Absent lacrimal punctum | Common - Between 50% and 80% cases |
| Alacrima | Common - Between 50% and 80% cases |
| Lacrimal gland aplasia | Common - Between 50% and 80% cases |
| Lacrimal gland hypoplasia | Common - Between 50% and 80% cases |
| Dacryocystitis | Common - Between 50% and 80% cases |
Other less frequent symptoms and clinical features
Patients with FGF10 gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Keratoconjunctivitis
- Keratoconjunctivitis sicca
- Xerostomia
- Epiphora
- Carious teeth
Not very common - Between 30% and 50% cases
- Recurrent corneal erosions
- Periorbital fullness
- Hypoplasia of the ulna
And 73 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to FGF10 gene
Here you will find a list of rare diseases related to the FGF10. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
APLASIA OF LACRIMAL AND SALIVARY GLANDS
Alternate names
APLASIA OF LACRIMAL AND SALIVARY GLANDS Is also known as congenital absence of lacrimal puncta and salivary glands, alsg
Description
Aplasia of the lacrimal and salivary glands (ALSG) is a rare autosomal dominant disorder characterized by aplasia, atresia or hypoplasia of the lacrimal and salivary glands leading to varying features since infancy such as recurrent eye infections, irritable eyes, epiphora, xerostomia, dental caries, dental erosion and oral inflammation.
More info about APLASIA OF LACRIMAL AND SALIVARY GLANDS
SOURCES: ORPHANET
LACRIMOAURICULODENTODIGITAL SYNDROME
Alternate names
LACRIMOAURICULODENTODIGITAL SYNDROME Is also known as ladd syndrome, levy-hollister syndrome, lacrimoauriculoradiodental syndrome, lard syndrome
Description
Lacrimoauriculodentodigital (LADD) syndrome is a multiple congenital anomaly syndrome characterized by hypoplasia, aplasia or atresia of the lacrimal system; anomalies of the ears and hearing loss; hypoplasias, apalsias or atresias of the salivary glands; dental anomalies and digital malformations.
Most common symptoms of LACRIMOAURICULODENTODIGITAL SYNDROME
- Irritability
- Autoimmunity
- Carious teeth
- Epiphora
- Keratoconjunctivitis sicca
More info about LACRIMOAURICULODENTODIGITAL SYNDROME
LACRIMOAURICULODENTODIGITAL SYNDROME; LADD
Alternate names
LACRIMOAURICULODENTODIGITAL SYNDROME; LADD Is also known as ladd syndrome, levy-hollister syndrome
Description
Lacrimoauriculodentodigital syndrome is a multiple congenital anomaly disorder mainly affecting lacrimal glands and ducts, salivary glands and ducts, ears, teeth, and distal limb segments (summary by Rohmann et al., 2006).
Most common symptoms of LACRIMOAURICULODENTODIGITAL SYNDROME; LADD
- Short stature
- Hearing impairment
- Hypertelorism
- Sensorineural hearing impairment
- Abnormal facial shape
More info about LACRIMOAURICULODENTODIGITAL SYNDROME; LADD
SOURCES: OMIM
Search interest in FGF10
Potential gene panels for FGF10 gene
LADD Syndrome, FGF10 Panel
United States.
By Center for Human Genetics, Inc
This panel specifically test the FGF10 gene.
More info about this panel United States.
Hypospadias Sequencing Panel Panel
United States.
By Genetic Services Laboratory University of Chicago Hypospadias Sequencing Panel that also includes the following genes: SALL1 BMP4 SOX2 SRD5A2 HNF1B MED12 WNT7A WT1 FBXL4 ZEB2
More info about this panel United States.
LADD syndrome (sequence analysis of FGF10 gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the FGF10 gene.
More info about this panel Portugal.
Aplasia of lacrimal and salivary glands (sequence analysis of FGF10 gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the FGF10 gene.
More info about this panel Portugal.
Aplasia of lacrimal and salivary glands (sequence analysis of FGF10 gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the FGF10 gene.
More info about this panel Portugal.
Hypospadias Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Hypospadias Sequencing Panel with CNV Detection that also includes the following genes: SALL1 BMP4 BMP7 SOX2 SRD5A2 HNF1B MED12 WNT7A WT1 FBXL4
More info about this panel United States.
Congenital Limb Malformation Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Congenital Limb Malformation Sequencing Panel with CNV Detection that also includes the following genes: ROR2 SALL1 BMP2 BMPR1B SF3B4 FBXW4 SHH BRCA2 SOX9 TBX15
More info about this panel United States.
Disorders of Sex Development (DSD) and Infertility Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Disorders of Sex Development (DSD) and Infertility Sequencing Panel with CNV Detection that also includes the following genes: ROR2 SALL1 BMP15 BMP4 SEMA3A SEMA3E BMP7 FOXL2 BRDT SOS1
More info about this panel United States.
Disorders of Sex Development (DSD) Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Disorders of Sex Development (DSD) Sequencing Panel with CNV Detection that also includes the following genes: ROR2 SALL1 BMP15 BMP4 SEMA3A BMP7 FOXL2 SOS1 SOX10 SOX2
More info about this panel United States.
Skeletal Disorders and Joint Problems Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Skeletal Disorders and Joint Problems Sequencing Panel with CNV Detection that also includes the following genes: RMRP ROR2 RUNX2 SALL1 BMP1 BMP2 BMPR1B SF3B4 SH3BP2 FBXW4
More info about this panel United States.
Aplasia of lacrimal and salivary glands Panel
Germany.
By Institute of Human Genetics Uniklinik RWTH Aachen
This panel specifically test the FGF10 gene.
More info about this panel Germany.
FGF10-related lacrimo-auriculo-dento-digital syndrome Panel
Germany.
By Institute of Human Genetics Uniklinik RWTH Aachen
This panel specifically test the FGF10 gene.
More info about this panel Germany.
LADD syndrome Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the FGF10 gene.
More info about this panel Germany.
AllNeuro panel Panel
Germany.
By Centogene AG - the Rare Disease Company AllNeuro panel that also includes the following genes: BCS1L ROR2 RPL10 BDNF RPS6KA3 RTN2 RYR1 SACS BIN1 SBF1
More info about this panel Germany.
Ectodermal dysplasia (including hypotrichosis and hypoplastic hair) Panel Panel
Germany.
By CeGaT GmbH Ectodermal dysplasia (including hypotrichosis and hypoplastic hair) Panel that also includes the following genes: BCS1L SNRPE SOX18 ST14 TRPS1 IFT122 WNT10A EDARADD SHOC2 LPAR6
More info about this panel Germany.
Selected Genetic Syndromes with skeletal involvement Panel Panel
Germany.
By CeGaT GmbH Selected Genetic Syndromes with skeletal involvement Panel that also includes the following genes: SALL1 SF3B4 TBCE TBX15 TBX3 TBX5 NIN SALL4 PCNT ORC6
More info about this panel Germany.
Syndromes with immunodeficiency Panel Panel
Germany.
By CeGaT GmbH Syndromes with immunodeficiency Panel that also includes the following genes: RMRP RUNX2 BLM SMARCAL1 STAT3 TBX1 TERC TERT TINF2 TREX1
More info about this panel Germany.
qGenEx Craniofacial Anomalies Panel
Spain.
By Quantitative Genomic Medicine Laboratories, SL qGenEx Craniofacial Anomalies that also includes the following genes: RUNX2 SALL1 TSHZ1 BMP4 SEMA3E SF3B4 SH3BP2 SHH SIX1 SIX3
More info about this panel Spain.
Limb Malformation: Sequencing Panel Panel
United States.
By EGL Genetic Diagnostics Eurofins Clinical Diagnostics Limb Malformation: Sequencing Panel that also includes the following genes: ROR2 SALL1 BMP2 BMPR1B FBXW4 SHH SOX9 TBX15 TBX3 TBX5
More info about this panel United States.
Skeletal Dysplasia: Sequencing Panel Panel
United States.
By EGL Genetic Diagnostics Eurofins Clinical Diagnostics Skeletal Dysplasia: Sequencing Panel that also includes the following genes: ROR2 RUNX2 SALL1 BMP2 BMPR1B FBXW4 SHH SHOX SLC25A12 SLC26A2
More info about this panel United States.
Skeletal Dysplasias NGS panel Panel
United States.
By Fulgent Genetics Fulgent Genetics Skeletal Dysplasias NGS panel that also includes the following genes: ROR2 RUNX2 SALL1 BMP2 BMPR1B FBXW4 SHH SLC25A12 SLC26A2 SMARCAL1
More info about this panel United States.
FGF10 Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the FGF10 gene.
More info about this panel United States.
Limb Malformations Panel Panel
Finland.
By Blueprint Genetics Limb Malformations Panel that also includes the following genes: SALL1 SF3B4 BRCA2 SMC1A TBX3 TBX5 WNT7A XRCC2 HDAC8 NSDHL
More info about this panel Finland.
FoundationOne® Heme Panel
United States.
By Foundation Medicine, Inc. FoundationOne® Heme that also includes the following genes: BCL6 BCL7A ROS1 RUNX1 BLM SDHA SDHB SDHC SDHD SF3B1
More info about this panel United States.
NeoTYPE® Discovery Profile for Solid Tumors Panel
United States.
By NeoGenomics Laboratories NeoGenomics Laboratories, Inc. NeoTYPE® Discovery Profile for Solid Tumors that also includes the following genes: BCL6 ROS1 RUNX1 BLM SDHA SDHB SDHC SDHD SF3B1 FOXL2
More info about this panel United States.
Caris MI TumorSeek 592-Gene NGS Panel Panel
United States.
By Caris Life Sciences Caris MI TumorSeek 592-Gene NGS Panel that also includes the following genes: BCL6 BCL7A BCL9 BCR ROS1 RPL10 RPL22 RPL5 RPN1 RUNX1
More info about this panel United States.
APLASIA OF LACRIMAL AND SALIVARY GLANDS Panel
Spain.
By Laboratorio de Genetica Clinica SL
This panel specifically test the FGF10 gene.
More info about this panel Spain.
Providence Personalized Medicine Panel - Solid Tumor Panel
United States.
By Providence Regional Laboratories Providence Health and Services Providence Personalized Medicine Panel - Solid Tumor that also includes the following genes: BCR ROS1 RUNX1 SDHA SDHB SDHC SDHD SF3B1 SRSF2 FOXL2
More info about this panel United States.
Lacrimoauriculodentodigital Syndrome (LADD) , Panel Massive Sequencing (NGS) FGF10, FGFR2, FGFR3 Genes Panel
Spain.
By Reference Laboratory Genetics Lacrimoauriculodentodigital Syndrome (LADD) , Panel Massive Sequencing (NGS) FGF10, FGFR2, FGFR3 Genes that also includes the following genes: FGF10 FGFR2 FGFR3
More info about this panel Spain.
Tempus xT assay Panel
United States.
By Tempus Labs, Inc. Tempus xT assay that also includes the following genes: BCL6 RIT1 BCL7A BCR ROS1 RPL5 RPS15 RPS6KB1 RUNX1 RXRA
More info about this panel United States.
Tempus xO assay Panel
United States.
By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2
More info about this panel United States.
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