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  3. DSC3

DSC3 gene related symptoms and diseases

All the information presented here about the DSC3 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,ORPHANET,OMIM,NCBIGENE, Mendelian Rare Disease Search Engine.

Table of contents:

Top 5 symptoms and clinical features associated to DSC3 gene

Symptoms // Phenotype % Cases
Hyperhidrosis Very Common - Between 80% and 100% cases
Sparse hair Very Common - Between 80% and 100% cases
Hypotrichosis Very Common - Between 80% and 100% cases
Sparse scalp hair Very Common - Between 80% and 100% cases
Aplasia/Hypoplasia of the eyebrow Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with DSC3 gene alterations may also develop some of the following symptoms and phenotypes:

  • Commonly - More than 50% cases

  • Skin vesicle
  • Sparse axillary hair
  • Sparse or absent eyelashes

Rare diseases associated to DSC3 gene

Here you will find a list of rare diseases related to the DSC3. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


HEREDITARY HYPOTRICHOSIS WITH RECURRENT SKIN VESICLES

Description

Hereditary hypotrichosis with recurrent skin vesicles is a very rare inherited hair loss disorder described in a family and characterized by sparse, fragile or absent hair on the scalp, eyebrows, eyelashes, axillae and rest of the body, associated with vesicle formation on various parts of the scalp and body which regularly burst and release watery fluid.

Most common symptoms of HEREDITARY HYPOTRICHOSIS WITH RECURRENT SKIN VESICLES

  • Hyperhidrosis
  • Sparse hair
  • Hypotrichosis
  • Sparse scalp hair
  • Aplasia/Hypoplasia of the eyebrow


More info about HEREDITARY HYPOTRICHOSIS WITH RECURRENT SKIN VESICLES

SOURCES: MESH ORPHANET OMIM


Potential gene panels for DSC3 gene

DSC3 Panel

Germany.

By Institute for Human Genetics University Clinic Freiburg

This panel specifically test the DSC3 gene.

More info about this panel
Germany.

AllNeuro panel Panel

Germany.

By Centogene AG - the Rare Disease Company AllNeuro panel that also includes the following genes: BCS1L ROR2 RPL10 BDNF RPS6KA3 RTN2 RYR1 SACS BIN1 SBF1

More info about this panel
Germany.

DSC3 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the DSC3 gene.

More info about this panel
United States.

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