DEK gene related symptoms and diseases
All the information presented here about the DEK gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,OMIM,NCBIGENE,ORPHANET, Mendelian Rare Disease Search Engine.
Rare diseases associated to DEK gene
Here you will find a list of rare diseases related to the DEK. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
ACUTE MYELOID LEUKEMIA WITH T(6;9)(P23;Q34)
Alternate names
ACUTE MYELOID LEUKEMIA WITH T(6;9)(P23;Q34) Is also known as aml with t(6;9)(p23;q34)
Description
Acute myeloid leukemia with t(6;9)(p23;q34) is a rare subtype of acute myeloid leukemia with recurrent genetic abnormalities characterized by clonal proliferation of poorly differentiated myeloid blasts in the bone marrow, blood, or other tissues in patients who present the t(6;9)(p23;q34) translocation. Frequently associated with multilineage bone marrow dysplasia, it usually presents with anemia, thrombocytopenia (often pancytopenia), and other nonspecific symptoms related to ineffective hematopoesis (fatigue, bleeding and bruising, recurrent infections, bone pain) and/or extramedullary site involvement (gingivitis, splenomegaly). Basophilia, as well as poor response to chemotherapy, has been reported.
More info about ACUTE MYELOID LEUKEMIA WITH T(6;9)(P23;Q34)
SOURCES: ORPHANET
Search interest in DEK
Potential gene panels for DEK gene
Acute myeloid leukemia (AML, sequence analysis of DEK gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the DEK gene.
More info about this panel Portugal.
RT-PCR t(6;9)(p23;q34)(DEK/CAN) Panel
Portugal.
By CGC Genetics RT-PCR t(6;9)(p23;q34)(DEK/CAN) that also includes the following genes: DEK NUP214
More info about this panel Portugal.
Acute nonlymphocytic leukemia Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the DEK gene.
More info about this panel Germany.
Onco microarray for MDS/AML Panel
United States.
By Pittsburgh Cytogenetics Laboratory University of Pittsburgh Medical Center Onco microarray for MDS/AML that also includes the following genes: BCR RPN1 RUNX1 SET TCF3 TERT TFG TP53 TRPS1 WT1
More info about this panel United States.
Caris MI TumorSeek 592-Gene NGS Panel Panel
United States.
By Caris Life Sciences Caris MI TumorSeek 592-Gene NGS Panel that also includes the following genes: BCL6 BCL7A BCL9 BCR ROS1 RPL10 RPL22 RPL5 RPN1 RUNX1
More info about this panel United States.
Tempus xO assay Panel
United States.
By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2
More info about this panel United States.
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