CTGF gene related symptoms and diseases

All the information presented here about the CTGF gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,OMIM,ORPHANET,HGNC.

Top 5 symptoms associated to CTGF gene



Symptoms // Phenotype % Cases
Skin ulcer Very Common - Between 80% and 100% cases
Narrow foramen obturatorium Very Common - Between 80% and 100% cases
Pulmonary fibrosis Very Common - Between 80% and 100% cases
Pulmonary arterial hypertension Very Common - Between 80% and 100% cases
Abnormality of the skin Very Common - Between 80% and 100% cases

Other less frequent symptoms

Patients with CTGF gene alterations may also develop some of the following symptoms and phenotypes:

Commonly - More than 50% cases

Nausea and vomiting

Not very common - Between 30% and 50% cases

Autoimmunity

Commonly - More than 50% cases

Dysphagia

Not very common - Between 30% and 50% cases

Gastroesophageal reflux

Commonly - More than 50% cases

Telangiectasia of the skin

Not very common - Between 30% and 50% cases

Abnormality of skin pigmentation Joint contracture of the hand Pulmonary infiltrates

And 18 more phenotypes.

Mendelian

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Rare diseases associated to CTGF gene

Here you will find a list of rare diseases related to the CTGF. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


DIFFUSE CUTANEOUS SYSTEMIC SCLEROSIS

Alternate names

DIFFUSE CUTANEOUS SYSTEMIC SCLEROSIS Is also known as diffuse cutaneous systemic scleroderma; progressive cutaneous systemic scleroderma; progressive cutaneous systemic sclerosis

Description

Diffuse cutaneous systemic sclerosis (dcSSc) is a subtype of Systemic Sclerosis (SSc; see this term) characterized by truncal and acral skin fibrosis with an early and significant incidence of diffuse involvement (interstitial lung disease, oliguric renal failure, diffuse gastrointestinal disease, and myocardial involvement).

Most common symptoms of DIFFUSE CUTANEOUS SYSTEMIC SCLEROSIS

  • Muscle weakness
  • Flexion contracture
  • Dysphagia
  • Renal insufficiency
  • Congestive heart failure


More info about DIFFUSE CUTANEOUS SYSTEMIC SCLEROSIS

SOURCES: ORPHANET

LIMITED CUTANEOUS SYSTEMIC SCLEROSIS

Alternate names

LIMITED CUTANEOUS SYSTEMIC SCLEROSIS Is also known as limited cutaneous systemic scleroderma

Description

Limited cutaneous systemic sclerosis (lcSSc) is a subtype of systemic sclerosis (SSc; see this term) characterized by the association of Raynaud's phenomenon with skin fibrosis limited to the hands, face, feet and forearms.

Most common symptoms of LIMITED CUTANEOUS SYSTEMIC SCLEROSIS

  • Dysphagia
  • Gastroesophageal reflux
  • Autoimmunity
  • Nausea and vomiting
  • Abnormality of skin pigmentation


More info about LIMITED CUTANEOUS SYSTEMIC SCLEROSIS

SOURCES: ORPHANET

Potential gene panels for CTGF gene

CTGF Panel

By Institute for Human Genetics University Clinic Freiburg in Germany.

This panel specifically test the CTGF gene.

More info about this panel

CTGF Panel

By Fulgent Genetics Fulgent Genetics in United States.

This panel specifically test the CTGF gene.

More info about this panel

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