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CISH gene related symptoms and diseases

All the information presented here about the CISH gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,OMIM,HGNC, Mendelian Rare Disease Search Engine.

Table of contents:

Top 5 symptoms and clinical features associated to CISH gene

Symptoms // Phenotype % Cases
Fever Common - Between 50% and 80% cases
Pain Uncommon - Between 30% and 50% cases
Elevated C-reactive protein level Uncommon - Between 30% and 50% cases
Gait imbalance Uncommon - Between 30% and 50% cases
Reduced consciousness/confusion Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with CISH gene alterations may also develop some of the following symptoms and phenotypes:

  • Not very common - Between 30% and 50% cases

  • Acute kidney injury
  • Abnormality of blood and blood-forming tissues
  • Hyperbilirubinemia
  • Nausea and vomiting
  • Retinopathy
  • Myalgia
  • Thrombocytopenia
  • Headache

And 11 more phenotypes, you can get all of them using our tools for rare diseases.

Rare diseases associated to CISH gene

Here you will find a list of rare diseases related to the CISH. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO

Description

Mycobacterium tuberculosis latently infects approximately one-third of humanity and is comparable only to human immunodeficiency virus (HIV; see {609423}) as a leading infectious cause of mortality worldwide. Obstacles for controlling TB infection include lengthy treatment regimens of 6 to 9 months, drug resistance, lack of a highly efficacious vaccine, and incomplete understanding of the factors that control infectivity and disease progression. Although only 10% of individuals infected with M. tuberculosis develop active disease, the immune responses associated with TB susceptibility or resistance are not known. In addition, it is not known why some individuals have disseminated TB that spreads to the meninges and central nervous system, while most people have localized disease in the lungs. A number of studies suggest that host genetic factors influence susceptibility and resistance to TB (review by Berrington and Hawn, 2007).

Most common symptoms of MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO

  • Pain
  • Fever
  • Fatigue
  • Immunodeficiency
  • Weight loss


More info about MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO

SOURCES: OMIM MESH

BACTEREMIA, SUSCEPTIBILITY TO, 2; BACTS2


More info about BACTEREMIA, SUSCEPTIBILITY TO, 2; BACTS2

SOURCES: OMIM

MALARIA

Description

Malaria is a preventable life-threatening parasitic disease caused by Plasmodium (P. ) parasites that are transmitted by Anophles mosquito bites to humans and is typically clinically characterized by attacks of fever, headache, chills and vomiting.

Most common symptoms of MALARIA

  • Cognitive impairment
  • Anemia
  • Fever
  • Respiratory distress
  • Headache


More info about MALARIA

SOURCES: OMIM ORPHANET


Potential gene panels for CISH gene

AllNeuro panel Panel

Germany.

By Centogene AG - the Rare Disease Company AllNeuro panel that also includes the following genes: BCS1L ROR2 RPL10 BDNF RPS6KA3 RTN2 RYR1 SACS BIN1 SBF1

More info about this panel
Germany.

CISH Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the CISH gene.

More info about this panel
United States.

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