CFB gene related symptoms and diseases
All the information presented here about the CFB gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,OMIM,HGNC,NCBIGENE, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to CFB gene
Symptoms // Phenotype | % Cases |
---|---|
Hypertension | Uncommon - Between 30% and 50% cases |
Thrombocytopenia | Uncommon - Between 30% and 50% cases |
Proteinuria | Uncommon - Between 30% and 50% cases |
Hematuria | Uncommon - Between 30% and 50% cases |
Acute kidney injury | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with CFB gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Elevated serum creatinine
- Hemolytic-uremic syndrome
- Increased blood urea nitrogen
- Anuria
- Microangiopathic hemolytic anemia
- Recurrent infections
- Pneumonia
- Meningitis
And 3 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to CFB gene
Here you will find a list of rare diseases related to the CFB. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
MACULAR DEGENERATION, AGE-RELATED, 14; ARMD14
ATYPICAL HEMOLYTIC-UREMIC SYNDROME WITH B FACTOR ANOMALY
Alternate names
ATYPICAL HEMOLYTIC-UREMIC SYNDROME WITH B FACTOR ANOMALY Is also known as hemolytic-uremic syndrome without diarrhea with b factor anomaly, ahus, susceptibility to, 4, atypical hus with b factor anomaly, ahus with b factor anomaly, d-hus with b factor anomaly
Most common symptoms of ATYPICAL HEMOLYTIC-UREMIC SYNDROME WITH B FACTOR ANOMALY
- Hypertension
- Thrombocytopenia
- Proteinuria
- Hematuria
- Acute kidney injury
More info about ATYPICAL HEMOLYTIC-UREMIC SYNDROME WITH B FACTOR ANOMALY
COMPLEMENT FACTOR B DEFICIENCY; CFBD
Most common symptoms of COMPLEMENT FACTOR B DEFICIENCY; CFBD
- Recurrent infections
- Pneumonia
- Meningitis
- Peritonitis
- Recurrent meningococcal disease
More info about COMPLEMENT FACTOR B DEFICIENCY; CFBD
SOURCES: OMIM
Search interest in CFB
Potential gene panels for CFB gene
Test for CFB-Related Atypical Hemolytic-Uremic Syndrome Panel
By Genome Diagnostics Laboratory University Medical Center Utrecht
This panel specifically test the CFB gene.
More info about this panelAHUS/MPGN panel Panel
By Genome Diagnostics Laboratory University Medical Center Utrecht AHUS/MPGN panel that also includes the following genes: CFB THBD C3 APLN CFHR5 CFH CFI CD46
More info about this panelGenetic Renal Panel Panel
By Molecular Otolaryngology and Renal Research Laboratories University of Iowa Hospital and Clinics Genetic Renal Panel that also includes the following genes: CFB THBD C3 ADAMTS13 CFHR3 MMACHC CFHR5 DGKE CFH CFHR1
More info about this panelAtypical Hemolytic Uremic Syndrome (aHUS) Genetic Susceptibility Panel Panel
By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center Atypical Hemolytic Uremic Syndrome (aHUS) Genetic Susceptibility Panel that also includes the following genes: CFB THBD C3 CFHR3 CFHR5 DGKE CFH CFHR1 CFI CD46
More info about this panelCFB Sequencing Panel
By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center
This panel specifically test the CFB gene.
More info about this panelCFB Deletion/duplication analysis Panel
By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center
This panel specifically test the CFB gene.
More info about this panelaHUS Genetic Susceptibility Deletion/duplication panel Panel
By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center aHUS Genetic Susceptibility Deletion/duplication panel that also includes the following genes: CFB THBD C3 DGKE CFI
More info about this panelThrombocytopenia Sequencing Panel Panel
By Genetic Services Laboratory University of Chicago Thrombocytopenia Sequencing Panel that also includes the following genes: CFB SRC TERC TERT THBD VWF WAS C3 ADAMTS13 ABCG5
More info about this panelThrombocytopenia Deletion/Duplication Panel Panel
By Genetic Services Laboratory University of Chicago Thrombocytopenia Deletion/Duplication Panel that also includes the following genes: CFB RUNX1 SRC TERC TERT THBD VWF WAS C3 ADAMTS13
More info about this panelExome PLUS Proteinuria/FSGS & Hematuria Panel
By Laboratory for Molecular Medicine Partners HealthCare Personalized Medicine Exome PLUS Proteinuria/FSGS & Hematuria that also includes the following genes: CFB TRPC6 TSC1 TSC2 C1QA C1QC WT1 C3 NPHS2 ADAMTS13
More info about this panelCFB. Complete sequencing Panel
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the CFB gene.
More info about this panelCFB. Complete sequencing Panel
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the CFB gene.
More info about this panelAtypical hemolytic uremic syndrome (NGS panel for 14 genes) Panel
By CGC Genetics Atypical hemolytic uremic syndrome (NGS panel for 14 genes) that also includes the following genes: CFB THBD C3 ADAMTS13 CFHR4 CFHR3 MMACHC CFHR5 DGKE CFH
More info about this panelAtypical hemolytic uremic syndrome 4 (sequence analysis of CFB gene) Panel
By CGC Genetics
This panel specifically test the CFB gene.
More info about this panelAtypical hemolytic uremic syndrome type 4 (deletions/duplications analysis of CFB gene) Panel
By CGC Genetics
This panel specifically test the CFB gene.
More info about this panelAtypical hemolytic uremic syndrome type 4 (deletions/duplications analysis of CFB gene) Panel
By CGC Genetics
This panel specifically test the CFB gene.
More info about this panelCFB Sequence Analysis Panel
By Translational Metabolic Laboratory Radboud University Medical Centre
This panel specifically test the CFB gene.
More info about this panelAtypical hemolytic-uremic syndrome 4 Panel
By Laboratory for Molecular Diagnostics Center for Nephrology and Metabolic Disorders
This panel specifically test the CFB gene.
More info about this panelAHUS/MPGN panel Panel
By Laboratory for Molecular Diagnostics Center for Nephrology and Metabolic Disorders AHUS/MPGN panel that also includes the following genes: CFB THBD C3 ADAMTS13 CFHR4 CFHR3 CLU CFHR5 CFH CFHR1
More info about this panelAtypical Hemolytic-Uremic Syndrome Panel Panel
By Laboratory for Molecular Diagnostics Center for Nephrology and Metabolic Disorders Atypical Hemolytic-Uremic Syndrome Panel that also includes the following genes: CFB THBD C3 ADAMTS13 CFHR4 CFHR3 CLU CFHR5 CFH CFHR1
More info about this panelAtypical hemolytic uremic syndrome susceptibility and related disorders NGS panel Panel
By Connective Tissue Gene Tests Atypical hemolytic uremic syndrome susceptibility and related disorders NGS panel that also includes the following genes: CFB THBD C3 ADAMTS13 CFHR3 MMACHC CFHR5 DGKE CFH CFHR1
More info about this panelAtypical hemolytic uremic syndrome susceptibility and related disorders Deletion/ Duplication panel Panel
By Connective Tissue Gene Tests Atypical hemolytic uremic syndrome susceptibility and related disorders Deletion/ Duplication panel that also includes the following genes: CFB THBD C3 ADAMTS13 CFHR3 MMACHC CFHR5 DGKE CFH CFHR1
More info about this panelAtypical hemolytic uremic syndrome susceptibility and related disorders Comprehensive panel Panel
By Connective Tissue Gene Tests Atypical hemolytic uremic syndrome susceptibility and related disorders Comprehensive panel that also includes the following genes: CFB THBD C3 ADAMTS13 CFHR3 MMACHC CFHR5 DGKE CFH CFHR1
More info about this panelAtypical hemolytic uremic syndrome Panel
By Northern Molecular Genetics Service Newcastle Upon Tyne Hospitals NHS Foundation Trust Atypical hemolytic uremic syndrome that also includes the following genes: CFB THBD C3 C5 ADAMTS13 INF2 MMACHC DGKE CFH CFI
More info about this panelAtypical hemolytic-uremic syndrome Panel
By Institute of Human Genetics Uniklinik RWTH Aachen Atypical hemolytic-uremic syndrome that also includes the following genes: CFB THBD C3 MMACHC DGKE CFH CFI CD46
More info about this panelHereditary kidney disorders - different panels Panel
By Institute of Human Genetics Uniklinik RWTH Aachen Hereditary kidney disorders - different panels that also includes the following genes: BCS1L ROBO2 CNNM2 CFB SALL1 ATXN10 SCNN1A SCNN1B SCNN1G SDCCAG8
More info about this panelAtypical hemolytic uremic syndrome panel Panel
By Centogene AG - the Rare Disease Company Atypical hemolytic uremic syndrome panel that also includes the following genes: CFB THBD C3 ADAMTS13 CFHR4 CFHR3 CFHR5 DGKE CFH CFHR1
More info about this panelHemolytic uremic syndrome Panel
By Centogene AG - the Rare Disease Company
This panel specifically test the CFB gene.
More info about this panelHemolytic Uremic Syndrome Panel Panel
By CeGaT GmbH Hemolytic Uremic Syndrome Panel that also includes the following genes: CFB THBD C3 ADAMTS13 CFHR4 CFHR3 CFHR5 DGKE CFH CFHR1
More info about this panelComplement deficiencies Panel Panel
By CeGaT GmbH Complement deficiencies Panel that also includes the following genes: CFB THBD SERPING1 C1QA C1QB C1QC C1R C1S C2 C3
More info about this panelCFB-Related Atypical Hemolytic-Uremic Syndrome Panel
By Secugen SL
This panel specifically test the CFB gene.
More info about this panelaHUS/DDD Genetic Evaluation Panel
By BloodCenter of Wisconsin Diagnostic Laboratories BloodCenter of Wisconsin, part of Versiti aHUS/DDD Genetic Evaluation that also includes the following genes: CFB THBD C3 C4BPA C4BPB ADAMTS13 CFHR4 CFHR3 CFHR5 DGKE
More info about this panelaCGH Deletion/Duplication Analysis Panel
By BloodCenter of Wisconsin Diagnostic Laboratories BloodCenter of Wisconsin, part of Versiti aCGH Deletion/Duplication Analysis that also includes the following genes: CFB RUNX1 STXBP2 TBXA2R THBD VWF WAS C3 C4BPA C4BPB
More info about this panelHemolytic-uremic, syndrome Panel
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases Hemolytic-uremic, syndrome that also includes the following genes: CFB THBD C3 CFHR4 CFHR3 CFHR5 CFH CFHR1 CFHR2 CFI
More info about this panelMacular Degeneration NGS Panel Panel
By Fulgent Genetics Fulgent Genetics Macular Degeneration NGS Panel that also includes the following genes: RLBP1 RPGR CFB TLR4 C2 C3 ELOVL4 RAX2 HMCN1 CNGB3
More info about this panelCFB Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the CFB gene.
More info about this panelPrimary Immunodeficiency Panel Panel
By Blueprint Genetics Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC CFB BLM SH2D1A SLC7A7 SMARCAL1 SMARCD2 SRP72 BTK
More info about this panelComplement System Disorder Panel Panel
By Blueprint Genetics Complement System Disorder Panel that also includes the following genes: CFB SPAG1 THBD SERPING1 RSPH1 C1QA C1QB C1QBP C1QC C1S
More info about this panelHemolytic Uremic Syndrome Panel Panel
By Blueprint Genetics Hemolytic Uremic Syndrome Panel that also includes the following genes: CFB THBD C3 ADAMTS13 CFHR5 DGKE CFH CFI CD46
More info about this panelComplement factor B deficiency Panel
By Bioarray
This panel specifically test the CFB gene.
More info about this panelHemolytic uremic syndrome, atypical, susceptibility to, 4 Panel
By Bioarray
This panel specifically test the CFB gene.
More info about this panelaHUS/TMA/C3 Glomerulopathy Gene Set Panel
By Genomics and Pathology Services Washington University in St. Louis aHUS/TMA/C3 Glomerulopathy Gene Set that also includes the following genes: CFB THBD C3 ADAMTS13 CFHR4 CFHR3 CFHR5 DGKE CFH CFHR1
More info about this panelATYPICAL HEMOLYTIC UREMIC SYNDROME Panel
By Laboratorio de Genetica Clinica SL ATYPICAL HEMOLYTIC UREMIC SYNDROME that also includes the following genes: CFB THBD C3 DGKE CFH CFI CD46
More info about this panelATYPICAL HEMOLYTIC UREMIC SYNDROME: NGS PANEL Panel
By Laboratorio de Genetica Clinica SL ATYPICAL HEMOLYTIC UREMIC SYNDROME: NGS PANEL that also includes the following genes: CFB THBD C1S C2 C3 C3AR1 C8A C9 CFHR4 CFHR3
More info about this panelAtypical Hemolytic Uremic Syndrome , Sequencing CFB Gene Panel
By Reference Laboratory Genetics
This panel specifically test the CFB gene.
More info about this panelAtypical Hemolytic Uremic Syndrome , Panel Massive Sequencing (NGS) 10 Genes Panel
By Reference Laboratory Genetics Atypical Hemolytic Uremic Syndrome , Panel Massive Sequencing (NGS) 10 Genes that also includes the following genes: CFB THBD C3 CFHR4 CFHR3 CFHR5 CFH CFHR1 CFI CD46
More info about this panelMacular Degeneration Related Disorders , Panel Massive Sequencing (NGS) 15 Genes Panel
By Reference Laboratory Genetics Macular Degeneration Related Disorders , Panel Massive Sequencing (NGS) 15 Genes that also includes the following genes: CFB C2 C3 C9 RAX2 HMCN1 CST3 CX3CR1 ARMS2 ABCA4
More info about this panelComplement System (Genetic Study) , Panel Massive Sequencing (NGS) 12 Genes Panel
By Reference Laboratory Genetics Complement System (Genetic Study) , Panel Massive Sequencing (NGS) 12 Genes that also includes the following genes: CFB THBD C3 ADAMTS13 CFHR3 CFHR5 DGKE CFH CFHR1 CFI
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