CDON gene related symptoms and diseases
All the information presented here about the CDON gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,ORPHANET,NCBIGENE,OMIM, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to CDON gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Global developmental delay | Rare - less than 30% cases |
| Anemia | Rare - less than 30% cases |
| Esophageal neoplasm | Rare - less than 30% cases |
| Giant hypertrophic gastritis | Rare - less than 30% cases |
| Neoplasm of the gastrointestinal tract | Rare - less than 30% cases |
Other less frequent symptoms and clinical features
Patients with CDON gene alterations may also develop some of the following symptoms and phenotypes:Rarely - Less than 30% cases
- Gastrointestinal obstruction
- Neoplasm of the stomach
- Neoplasm of the colon
- Neoplasm of the rectum
- Seizures
- Neoplasm of the small intestine
- Mastocytosis
- Soft tissue sarcoma
And 60 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to CDON gene
Here you will find a list of rare diseases related to the CDON. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
HOLOPROSENCEPHALY 11; HPE11
Most common symptoms of HOLOPROSENCEPHALY 11; HPE11
- Global developmental delay
- Microcephaly
- Cleft palate
- Agenesis of corpus callosum
- Proptosis
More info about HOLOPROSENCEPHALY 11; HPE11
SOURCES: OMIM
GASTROINTESTINAL STROMAL TUMOR
Alternate names
GASTROINTESTINAL STROMAL TUMOR Is also known as gastrointestinal stromal sarcoma, gist
Description
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal neoplasm of the gastrointestinal (GI) tract, typically presenting in adults over the age of 40 (mean age 63), and only rarely in children, in various regions of the GI tract, most commonly the stomach or small intestine but also less commonly in the esophagus, appendix, rectum and colon. GISTs can be asymptomatic or present with various non-specific signs, depending on the location and size of tumor, such as loss of appetite, anemia, weight loss, fatigue, abdominal discomfort or fullness, nausea, vomiting, as well as an abdominal mass, blood in stool, and intestinal obstruction. GISTs can also be seen in familial syndromes such as Carney triad and neurofibromatosis type 1.
Most common symptoms of GASTROINTESTINAL STROMAL TUMOR
- Neoplasm
- Pain
- Anemia
- Fever
- Fatigue
More info about GASTROINTESTINAL STROMAL TUMOR
PITUITARY STALK INTERRUPTION SYNDROME
Alternate names
PITUITARY STALK INTERRUPTION SYNDROME Is also known as psis, ectopic neurohypophysis
Description
Pituitary stalk interruption syndrome (PSIS) is a congenital abnormality of the pituitary that is responsible for pituitary deficiency and is usually characterized by the triad of a very thin or interrupted pituitary stalk, an ectopic (or absent) posterior pituitary (EPP) and hypoplasia or aplasia of the anterior pituitary visible on MRI. In some patients the abnormality may be limited to EPP (also called ectopic neurohypophysis) or to an interrupted pituitary stalk.
Most common symptoms of PITUITARY STALK INTERRUPTION SYNDROME
- Intellectual disability
- Seizures
- Global developmental delay
- Short stature
- Failure to thrive
More info about PITUITARY STALK INTERRUPTION SYNDROME
SOURCES: ORPHANET
SEMILOBAR HOLOPROSENCEPHALY
Description
Semilobar holoprosencephaly is one of the classical forms of holoprosencephaly (HPE; see this term) in which the left and right frontal and parietal lobes are fused and the interhemispheric fissure is only present posteriorly.
More info about SEMILOBAR HOLOPROSENCEPHALY
SOURCES: ORPHANET
SEPTOPREOPTIC HOLOPROSENCEPHALY
Alternate names
SEPTOPREOPTIC HOLOPROSENCEPHALY Is also known as septopreoptic hpe
Description
Septopreoptic holoprosencephaly (HPE) is a very rare subtype of lobar HPE (see this term) characterized by midline fusion limited to the septal and/or preoptic regions of the telencephalon without a significant frontal neocortical fusion.
More info about SEPTOPREOPTIC HOLOPROSENCEPHALY
SOURCES: ORPHANET
LOBAR HOLOPROSENCEPHALY
Description
Lobar holoprosencephaly is the mildest classical form of holoprosencephaly (HPE; see this term) characterized by separation of the right and left cerebral hemispheres and lateral ventricules with some continuity across the frontal neocortex, especially rostrally and ventrally.
More info about LOBAR HOLOPROSENCEPHALY
SOURCES: ORPHANET
ALOBAR HOLOPROSENCEPHALY
Description
Alobar holoprosencephaly is the most severe classical form of holoprosencephaly (HPE; see this term) characterized by a single brain ventricle and no interhemispheric fissure.
More info about ALOBAR HOLOPROSENCEPHALY
SOURCES: ORPHANET
MIDLINE INTERHEMISPHERIC VARIANT OF HOLOPROSENCEPHALY
Alternate names
MIDLINE INTERHEMISPHERIC VARIANT OF HOLOPROSENCEPHALY Is also known as mihf, mihv, middle interhemispheric variant of holoprosencephaly, mih, mih type hpe, syntelencephaly, middle interhemispheric fusion variant
Description
Midline interhemispheric variant of holoprosencephaly (MIH) or syntelencephaly is a form of holoprosencephaly (HPE; see this term) characterized by non-separation of the posterior frontal and parietal lobes, normally-formed callosal genu and splenium, absence of the callosal body, normally-separated hypothalamus and lentiform nucleus, and frequent heterotopic gray matter.
More info about MIDLINE INTERHEMISPHERIC VARIANT OF HOLOPROSENCEPHALY
SOURCES: ORPHANET
Search interest in CDON
Potential gene panels for CDON gene
NGS Epilepsy/Seizure Panel Panel
United States.
By Greenwood Genetic Center Diagnostic Laboratories Greenwood Genetic Center NGS Epilepsy/Seizure Panel that also includes the following genes: SCN1A SCN1B SCN2A SCN5A SCN8A SCN9A SHH ST3GAL3 ST3GAL5 STIL
More info about this panel United States.
Comprehensive Brain Malformation Panel Panel
United States.
By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University Comprehensive Brain Malformation Panel that also includes the following genes: SHH STIL SIX3 SLC9A6 SOX2 CDKL5 TGIF1 MED12 CEP41 TUBA8
More info about this panel United States.
Holoprosencephaly Panel
United States.
By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University Holoprosencephaly that also includes the following genes: SHH SIX3 TGIF1 ZIC2 CDON DISP1 DLL1 FGF8 FOXH1 GAS1
More info about this panel United States.
Holoprosencephaly Sequencing Panel Panel
United States.
By Genetic Services Laboratory University of Chicago Holoprosencephaly Sequencing Panel that also includes the following genes: SHH STIL SIX3 TGIF1 ZIC2 CDON FGF8 FGFR1 GLI2 PTCH1
More info about this panel United States.
Holoprosencephaly Deletion/Duplication Panel Panel
United States.
By Genetic Services Laboratory University of Chicago Holoprosencephaly Deletion/Duplication Panel that also includes the following genes: SHH STIL SIX3 TGIF1 ZIC2 CDON FGF8 FGFR1 GLI2 PTCH1
More info about this panel United States.
CDON. Complete sequencing Panel
Spain.
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the CDON gene.
More info about this panel Spain.
Holoprosencephaly 11 (sequence analysis of CDON gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the CDON gene.
More info about this panel Portugal.
Holoprosencephaly (NGS panel for 9 genes) Panel
Portugal.
By CGC Genetics Holoprosencephaly (NGS panel for 9 genes) that also includes the following genes: SHH SIX3 TGIF1 ZIC2 CDON FGF8 GLI2 GLI3 PTCH1
More info about this panel Portugal.
Holoprosencephaly, Autosomal Dominant, Nonsyndromic, Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Holoprosencephaly, Autosomal Dominant, Nonsyndromic, Sequencing Panel with CNV Detection that also includes the following genes: SHH SIX3 TGIF1 ZIC2 CDON DISP1 DLL1 FGF8 FOXH1 GAS1
More info about this panel United States.
Holoprosencephaly-11 via CDON Gene Sequencing with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics
This panel specifically test the CDON gene.
More info about this panel United States.
Mental retardation - different panels Panel
Germany.
By Institute of Human Genetics Uniklinik RWTH Aachen Mental retardation - different panels that also includes the following genes: RGS7 RIT1 RMRP BCS1L RPL10 RPS6KA3 RRAS SALL1 SC5D ATXN10
More info about this panel Germany.
Brain Malformations / Neuronal Migration Disorders Panel
Germany.
By MGZ Medical Genetics Center Brain Malformations / Neuronal Migration Disorders that also includes the following genes: RPL10 RPS6KA3 SCN1A SCN1B SCN2A SCN8A SGCE SGSH STIL SLC16A2
More info about this panel Germany.
Holoprosencephaly Panel
Germany.
By MGZ Medical Genetics Center Holoprosencephaly that also includes the following genes: CDON DISP1 FGF8 FOXH1 GLI2 NODAL PTCH1
More info about this panel Germany.
Holoprosencephaly panel Panel
Germany.
By Centogene AG - the Rare Disease Company Holoprosencephaly panel that also includes the following genes: SHH SIX3 TGIF1 ZIC2 CDON FGF8 GLI2 GLI3 PTCH1
More info about this panel Germany.
AllNeuro panel Panel
Germany.
By Centogene AG - the Rare Disease Company AllNeuro panel that also includes the following genes: BCS1L ROR2 RPL10 BDNF RPS6KA3 RTN2 RYR1 SACS BIN1 SBF1
More info about this panel Germany.
Holoprosencephaly 11 Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the CDON gene.
More info about this panel Germany.
Holoprosencephaly Panel Panel
Germany.
By CeGaT GmbH Holoprosencephaly Panel that also includes the following genes: SHH SIX3 TGIF1 ZIC2 CDON GLI2 PTCH1
More info about this panel Germany.
Holoprosencephaly Panel Panel
Germany.
By CeGaT GmbH Holoprosencephaly Panel that also includes the following genes: SHH SIX3 TGIF1 ZIC2 CDON GLI2 PTCH1
More info about this panel Germany.
Single gene testing CDON Panel
Germany.
By CeGaT GmbH
This panel specifically test the CDON gene.
More info about this panel Germany.
qGenEx Craniofacial Anomalies Panel
Spain.
By Quantitative Genomic Medicine Laboratories, SL qGenEx Craniofacial Anomalies that also includes the following genes: RUNX2 SALL1 TSHZ1 BMP4 SEMA3E SF3B4 SH3BP2 SHH SIX1 SIX3
More info about this panel Spain.
HOLOPROSENCEPHALY Panel
Spain.
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases HOLOPROSENCEPHALY that also includes the following genes: SIX3 TGIF1 ZIC2 CDON DLL1 FGF8 FOXH1 GAS1 GLI2 NODAL
More info about this panel Spain.
Epilepsy NGS Panel Panel
United States.
By Fulgent Genetics Fulgent Genetics Epilepsy NGS Panel that also includes the following genes: BCS1L SCN10A SCN1A SCN1B SCN2A SCN2B SCN3A SCN4A SCN4B SCN5A
More info about this panel United States.
Holoproscencephaly NGS Panel Panel
United States.
By Fulgent Genetics Fulgent Genetics Holoproscencephaly NGS Panel that also includes the following genes: SHH SIX3 TGIF1 ZIC2 CDON GLI2 PTCH1
More info about this panel United States.
CDON Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the CDON gene.
More info about this panel United States.
Comprehensive Epilepsy NGS Panel Panel
United States.
By Fulgent Genetics Fulgent Genetics Comprehensive Epilepsy NGS Panel that also includes the following genes: BCS1L RYR3 SCN10A SCN1A SCN1B SCN2A SCN2B SCN3A SCN4A SCN4B
More info about this panel United States.
Holoprosencephaly Panel Panel
Finland.
By Blueprint Genetics Holoprosencephaly Panel that also includes the following genes: SHH SIX3 TGIF1 ZIC2 CDON FGF8 FGFR1 FOXH1 GLI2 GLI3
More info about this panel Finland.
Holoprosencephaly type 11 Panel
Spain.
By Bioarray
This panel specifically test the CDON gene.
More info about this panel Spain.
HOLOPROSENCEPHALY NGS PANEL Panel
Spain.
By Laboratorio de Genetica Clinica SL HOLOPROSENCEPHALY NGS PANEL that also includes the following genes: SHH SIX3 TGIF1 ZIC2 CDON DLL1 FGF8 FGFR1 FOXH1 GAS1
More info about this panel Spain.
Holoprosencephaly , Sequencing CDON Gene Panel
Spain.
By Reference Laboratory Genetics
This panel specifically test the CDON gene.
More info about this panel Spain.
Holoprosencephaly, Panel Massive Sequencing (NGS) 8 Genes Panel
Spain.
By Reference Laboratory Genetics Holoprosencephaly, Panel Massive Sequencing (NGS) 8 Genes that also includes the following genes: SIX3 TGIF1 ZIC2 CDON FGF8 GLI2 NODAL PTCH1
More info about this panel Spain.
Holoprosencephaly: gene sequencing panel Panel
Canada.
By CEN4GEN Institute for Genomics and Molecular Diagnostics Holoprosencephaly: gene sequencing panel that also includes the following genes: SHH SIX3 TGIF1 ZIC2 CDON DISP1 DLL1 FGF8 FOXH1 GAS1
More info about this panel Canada.
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