CD3G gene related symptoms and diseases
All the information presented here about the CD3G gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,HGNC,OMIM,NCBIGENE, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to CD3G gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Failure to thrive | Very Common - Between 80% and 100% cases |
| Abnormal intestine morphology | Very Common - Between 80% and 100% cases |
| Decreased proportion of CD8-positive T cells | Very Common - Between 80% and 100% cases |
| Bronchiolitis obliterans | Very Common - Between 80% and 100% cases |
| Bronchiolitis | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with CD3G gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Decrease in T cell count
- Severe combined immunodeficiency
- Autoimmune hemolytic anemia
- Combined immunodeficiency
- Inflammation of the large intestine
- Lymphopenia
- Anemia
- Recurrent otitis media
And 8 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to CD3G gene
Here you will find a list of rare diseases related to the CD3G. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
COMBINED IMMUNODEFICIENCY DUE TO CD3GAMMA DEFICIENCY
Alternate names
COMBINED IMMUNODEFICIENCY DUE TO CD3GAMMA DEFICIENCY Is also known as scid-like immunodeficiency, t cell-partial, b cell-positive, nk cell-positive, cd3-gamma deficiency
Description
Combined immunodeficiency due to CD3gamma deficiency is an extremely rare genetic combined primary immunodeficiency characterized by a selective partial lymphopenia (T+/-B+NK+) phenotype and decreased CD3 complex resulting in a variable but usually mild clinical presentation ranging from asymptomatic until adulthood to high susceptibility to infections from early infancy with predominant automimmune manifestations.
Most common symptoms of COMBINED IMMUNODEFICIENCY DUE TO CD3GAMMA DEFICIENCY
- Failure to thrive
- Anemia
- Immunodeficiency
- Recurrent infections
- Recurrent respiratory infections
More info about COMBINED IMMUNODEFICIENCY DUE TO CD3GAMMA DEFICIENCY
Search interest in CD3G
Potential gene panels for CD3G gene
Combined immunodeficiency due to CD3gamma deficiency (sequence analysis of CD3G gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the CD3G gene.
More info about this panel Portugal.
CD3G Panel
Netherlands.
By Genome Diagnostics Laboratory University Medical Center Utrecht
This panel specifically test the CD3G gene.
More info about this panel Netherlands.
Severe combined immunodeficiency (SCID) panel Panel
Netherlands.
By Genome Diagnostics Laboratory University Medical Center Utrecht Severe combined immunodeficiency (SCID) panel that also includes the following genes: STAT5B STIM1 TBX1 CD40 CD40LG ZAP70 CD3D CD3E CD3G CD8A
More info about this panel Netherlands.
CentoICU platinum plus Panel
Germany.
By Centogene AG - the Rare Disease Company CentoICU platinum plus that also includes the following genes: RMRP BCS1L BDNF RPS19 RPS6KA3 SALL1 SCN1A SCN2A SFTPB SFTPC
More info about this panel Germany.
New Born testing (CentoICU) Panel
Germany.
By Centogene AG - the Rare Disease Company New Born testing (CentoICU) that also includes the following genes: RMRP BCS1L BDNF RPS19 RPS6KA3 SALL1 SCN1A SCN2A SFTPB SFTPC
More info about this panel Germany.
Cone-rod dystrophy type 17 Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the CD3G gene.
More info about this panel Germany.
Combined immunodeficiencies Panel Panel
Germany.
By CeGaT GmbH Combined immunodeficiencies Panel that also includes the following genes: RMRP SEMA3E STAT5B STIM1 STK4 TAPBP TBX1 THBD TNFRSF4 CD40
More info about this panel Germany.
Invitae Comprehensive Severe Combined Immunodeficiency (SCID) and Combined Immunodeficiency (CID) Panel Panel
United States.
By Invitae Invitae Comprehensive Severe Combined Immunodeficiency (SCID) and Combined Immunodeficiency (CID) Panel that also includes the following genes: STK4 TAPBP TNFRSF4 CD27 CD40LG ZAP70 CARD11 CD3D CD3E CD3G
More info about this panel United States.
Invitae Monogenic Inflammatory Bowel Disease Panel Panel
United States.
By Invitae Invitae Monogenic Inflammatory Bowel Disease Panel that also includes the following genes: SH2D1A BTK STAT1 STAT3 STIM1 STXBP2 CD40LG WAS ZAP70 AICDA
More info about this panel United States.
Invitae Primary Immunodeficiency Panel Panel
United States.
By Invitae Invitae Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC SEMA3E SH2D1A SH3BP2 SLC7A7 SMARCAL1 BTK STAT1 STAT2
More info about this panel United States.
Invitae Combined Immunodeficiency (CID) Panel Panel
United States.
By Invitae Invitae Combined Immunodeficiency (CID) Panel that also includes the following genes: STK4 TAPBP TNFRSF4 CD27 CD40LG ZAP70 CARD11 CD3G CD8A LRBA
More info about this panel United States.
CD3G Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the CD3G gene.
More info about this panel United States.
Primary Immunodeficiency Panel Panel
Finland.
By Blueprint Genetics Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC CFB BLM SH2D1A SLC7A7 SMARCAL1 SMARCD2 SRP72 BTK
More info about this panel Finland.
Severe Combined Immunodeficiency Panel Panel
Finland.
By Blueprint Genetics Severe Combined Immunodeficiency Panel that also includes the following genes: RMRP BLM SH2D1A SMARCAL1 STAT1 STAT2 STAT3 STAT5B STIM1 STK4
More info about this panel Finland.
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