CD3D gene related symptoms and diseases
All the information presented here about the CD3D gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,OMIM,HGNC,ORPHANET, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to CD3D gene
Symptoms // Phenotype | % Cases |
---|---|
Failure to thrive | Uncommon - Between 30% and 50% cases |
Fever | Uncommon - Between 30% and 50% cases |
Respiratory distress | Uncommon - Between 30% and 50% cases |
Diarrhea | Uncommon - Between 30% and 50% cases |
Immunodeficiency | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with CD3D gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Recurrent respiratory infections
- Respiratory tract infection
- Tachycardia
- Hepatic failure
- Hepatitis
- Recurrent otitis media
- Chronic diarrhea
- Lymphopenia
And 3 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to CD3D gene
Here you will find a list of rare diseases related to the CD3D. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
IMMUNODEFICIENCY 19; IMD19
Alternate names
IMMUNODEFICIENCY 19; IMD19 Is also known as scid, t cell-negative, b cell-positive, nk cell-positive, cd3-delta deficiency, severe combined immunodeficiency, t cell-negative, b cell-positive, nk cell-positive
Description
Immunodeficiency-19 (IMD19) is an autosomal recessive form of severe combined immunodeficiency (SCID) characterized by onset in early infancy of recurrent bacterial, viral, and fungal infections. Patients usually have chronic diarrhea, recurrent respiratory infections, and failure to thrive. Immunologic work-up shows a T cell-negative, B cell-positive, natural killer (NK) cell-positive phenotype. The disorder is lethal in early childhood without bone marrow transplantation (summary by Yu et al., 2011).
Most common symptoms of IMMUNODEFICIENCY 19; IMD19
- Failure to thrive
- Fever
- Respiratory distress
- Diarrhea
- Immunodeficiency
More info about IMMUNODEFICIENCY 19; IMD19
SOURCES: OMIM
T-B+ SEVERE COMBINED IMMUNODEFICIENCY DUE TO CD3DELTA/CD3EPSILON/CD3ZETA
Alternate names
T-B+ SEVERE COMBINED IMMUNODEFICIENCY DUE TO CD3DELTA/CD3EPSILON/CD3ZETA Is also known as t-b+ scid due to cd3delta/cd3epsilon/cd3zeta
More info about T-B+ SEVERE COMBINED IMMUNODEFICIENCY DUE TO CD3DELTA/CD3EPSILON/CD3ZETA
SOURCES: ORPHANET
Search interest in CD3D
Potential gene panels for CD3D gene
Severe Combined Immunodeficiency (SCID Including Omenn Syndrome ): Eight-gene Profile (IL2RG, JAK3, RAG1, RAG2, IL7R, ADA, CD3D, CD3E) (Full Gene Sequencing) Panel
By Molecular Diagnostic Laboratory University of Alberta Severe Combined Immunodeficiency (SCID Including Omenn Syndrome ): Eight-gene Profile (IL2RG, JAK3, RAG1, RAG2, IL7R, ADA, CD3D, CD3E) (Full Gene Sequencing) that also includes the following genes: CD3D CD3E ADA IL2RG IL7R JAK3 RAG1 RAG2
More info about this panelSevere Combined Immunodeficiency (SCID Including Omenn Syndrome): Nine-gene Profile (IL2RG), JAK3, RAG1, RAG2, IL7R, ADA, CD3D, CD3E, DCLREC1C [Artemis]) (Full Gene Sequencing) Panel
By Molecular Diagnostic Laboratory University of Alberta Severe Combined Immunodeficiency (SCID Including Omenn Syndrome): Nine-gene Profile (IL2RG), JAK3, RAG1, RAG2, IL7R, ADA, CD3D, CD3E, DCLREC1C [Artemis]) (Full Gene Sequencing) that also includes the following genes: CD3D CD3E DCLRE1C ADA IL2RG IL7R JAK3 RAG1 RAG2
More info about this panelSevere Combined Immunodeficiency (SCID): CD3D (Full Gene Sequencing) Panel
By Molecular Diagnostic Laboratory University of Alberta
This panel specifically test the CD3D gene.
More info about this panelSevere Combined Immunodeficiency (SCID): CD3D (Known Mutation) Panel
By Molecular Diagnostic Laboratory University of Alberta
This panel specifically test the CD3D gene.
More info about this panelSevere Combined Immunodeficiency (SCID): Three-gene Profile (IL7R, CD3D, CD3E) (Full Gene Sequencing) Panel
By Molecular Diagnostic Laboratory University of Alberta Severe Combined Immunodeficiency (SCID): Three-gene Profile (IL7R, CD3D, CD3E) (Full Gene Sequencing) that also includes the following genes: CD3D CD3E IL7R
More info about this panelSevere Combined Immunodeficiency and T Cell Disorders Panel by next-generation sequencing (NGS) Panel
By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center Severe Combined Immunodeficiency and T Cell Disorders Panel by next-generation sequencing (NGS) that also includes the following genes: RMRP STAT5B STIM1 TBX1 FOXN1 ZAP70 CD3D CD3E DCLRE1C ADA
More info about this panelCD3D Sequencing Panel
By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center
This panel specifically test the CD3D gene.
More info about this panelSevere Combined Immunodeficiency and T Cell Disorders Deletion/Duplication Panel Panel
By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center Severe Combined Immunodeficiency and T Cell Disorders Deletion/Duplication Panel that also includes the following genes: RMRP STAT5B STIM1 TBX1 FOXN1 ZAP70 CD3D CD3E ADA NHEJ1
More info about this panelCD3D Deletion/duplication analysis Panel
By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center
This panel specifically test the CD3D gene.
More info about this panelCD3D Panel
By Genome Diagnostics Laboratory University Medical Center Utrecht
This panel specifically test the CD3D gene.
More info about this panelSevere combined immunodeficiency (SCID) panel Panel
By Genome Diagnostics Laboratory University Medical Center Utrecht Severe combined immunodeficiency (SCID) panel that also includes the following genes: STAT5B STIM1 TBX1 CD40 CD40LG ZAP70 CD3D CD3E CD3G CD8A
More info about this panelB-positive SCID panel Panel
By Centogene AG - the Rare Disease Company B-positive SCID panel that also includes the following genes: RMRP STAT5B STIM1 TBX1 FOXN1 ZAP70 CD3D CD3E CD247 ORAI1
More info about this panelComprehensive SCID panel Panel
By Centogene AG - the Rare Disease Company Comprehensive SCID panel that also includes the following genes: RMRP STAT5B STIM1 TBX1 FOXN1 ZAP70 CD3D CD3E CD247 DCLRE1C
More info about this panelImmunodeficiency type 19 Panel
By Centogene AG - the Rare Disease Company
This panel specifically test the CD3D gene.
More info about this panelCentoICU platinum plus Panel
By Centogene AG - the Rare Disease Company CentoICU platinum plus that also includes the following genes: RMRP BCS1L BDNF RPS19 RPS6KA3 SALL1 SCN1A SCN2A SFTPB SFTPC
More info about this panelNew Born testing (CentoICU) Panel
By Centogene AG - the Rare Disease Company New Born testing (CentoICU) that also includes the following genes: RMRP BCS1L BDNF RPS19 RPS6KA3 SALL1 SCN1A SCN2A SFTPB SFTPC
More info about this panelCombined immunodeficiencies Panel Panel
By CeGaT GmbH Combined immunodeficiencies Panel that also includes the following genes: RMRP SEMA3E STAT5B STIM1 STK4 TAPBP TBX1 THBD TNFRSF4 CD40
More info about this panelInvitae Comprehensive Severe Combined Immunodeficiency (SCID) Panel Panel
By Invitae Invitae Comprehensive Severe Combined Immunodeficiency (SCID) Panel that also includes the following genes: ZAP70 CD3D CD3E CD247 DCLRE1C ADA CORO1A NHEJ1 AK2 IL2RG
More info about this panelInvitae Comprehensive Severe Combined Immunodeficiency (SCID) and Combined Immunodeficiency (CID) Panel Panel
By Invitae Invitae Comprehensive Severe Combined Immunodeficiency (SCID) and Combined Immunodeficiency (CID) Panel that also includes the following genes: STK4 TAPBP TNFRSF4 CD27 CD40LG ZAP70 CARD11 CD3D CD3E CD3G
More info about this panelInvitae Primary Immunodeficiency Panel Panel
By Invitae Invitae Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC SEMA3E SH2D1A SH3BP2 SLC7A7 SMARCAL1 BTK STAT1 STAT2
More info about this panelInvitae T-B+NK+ Severe Combined Immunodeficiency (SCID) Panel Panel
By Invitae Invitae T-B+NK+ Severe Combined Immunodeficiency (SCID) Panel that also includes the following genes: CD3D CD3E CD247 CORO1A IL7R PTPRC
More info about this panelSevere Combined Immunodeficiency (SCID) B+: Sequencing Panel Panel
By EGL Genetic Diagnostics Eurofins Clinical Diagnostics Severe Combined Immunodeficiency (SCID) B+: Sequencing Panel that also includes the following genes: STAT5B STIM1 TBX1 FOXN1 ZAP70 CD3D CD3E CD247 ORAI1 IL2RG
More info about this panelSevere Combined Immunodeficiency (SCID) B+/B-: Sequencing Panel Panel
By EGL Genetic Diagnostics Eurofins Clinical Diagnostics Severe Combined Immunodeficiency (SCID) B+/B-: Sequencing Panel that also includes the following genes: STAT5B STIM1 TBX1 FOXN1 ZAP70 CD3D CD3E CD247 DCLRE1C ADA
More info about this panelCD3D Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the CD3D gene.
More info about this panelPrimary Immunodeficiency Panel Panel
By Blueprint Genetics Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC CFB BLM SH2D1A SLC7A7 SMARCAL1 SMARCD2 SRP72 BTK
More info about this panelSevere Combined Immunodeficiency Panel Panel
By Blueprint Genetics Severe Combined Immunodeficiency Panel that also includes the following genes: RMRP BLM SH2D1A SMARCAL1 STAT1 STAT2 STAT3 STAT5B STIM1 STK4
More info about this panelSevere Combined Immunodeficiency NGS and Deletion/Duplication Panel Panel
By DDC Clinic Molecular Diagnostics Laboratory DDC Clinic, Center for Special Needs Children Severe Combined Immunodeficiency NGS and Deletion/Duplication Panel that also includes the following genes: CD3D CD3E DCLRE1C ADA IL2RG IL7R JAK3 RAG1 RAG2
More info about this panelCD3D Gene Sequencing and Deletion/Duplication Analysis Panel
By DDC Clinic Molecular Diagnostics Laboratory DDC Clinic, Center for Special Needs Children
This panel specifically test the CD3D gene.
More info about this panelSEVERE COMBINED IMMUNODEFICIENCY (SCID) T- B+ NK+, (AUTOSOMAL RECESSIVE) Panel
By Laboratorio de Genetica Clinica SL SEVERE COMBINED IMMUNODEFICIENCY (SCID) T- B+ NK+, (AUTOSOMAL RECESSIVE) that also includes the following genes: CD3D CD3E IL7R PTPRC
More info about this panelSEVERE COMBINED IMMUNODEFICIENCY (SCID): NGS PANEL Panel
By Laboratorio de Genetica Clinica SL SEVERE COMBINED IMMUNODEFICIENCY (SCID): NGS PANEL that also includes the following genes: STAT1 STIM1 FOXN1 ZAP70 CARD11 CD3D CD3E CD247 DCLRE1C ADA
More info about this panelSevere Combined Immune Deficiency (SCID) , Panel Massive Sequencing (NGS) 18 Genes Panel
By Reference Laboratory Genetics Severe Combined Immune Deficiency (SCID) , Panel Massive Sequencing (NGS) 18 Genes that also includes the following genes: STAT5B STIM1 FOXN1 ZAP70 CD3D CD3E DCLRE1C ADA NHEJ1 ORAI1
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