CAST gene related symptoms and diseases
All the information presented here about the CAST gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,NCBIGENE,HGNC,ORPHANET, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to CAST gene
Symptoms // Phenotype | % Cases |
---|---|
Hyperkeratosis | Very Common - Between 80% and 100% cases |
Erythema | Very Common - Between 80% and 100% cases |
Scarring | Very Common - Between 80% and 100% cases |
Papule | Very Common - Between 80% and 100% cases |
Palmoplantar keratoderma | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with CAST gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Epidermal acanthosis
- Scaling skin
- Fragile skin
- Oral leukoplakia
- Onycholysis
- Leukonychia
- Cheilitis
- Acantholysis
And 2 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to CAST gene
Here you will find a list of rare diseases related to the CAST. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
PEELING SKIN-LEUKONYCHIA-ACRAL PUNCTATE KERATOSES-CHEILITIS-KNUCKLE PADS SYNDROME
Alternate names
PEELING SKIN-LEUKONYCHIA-ACRAL PUNCTATE KERATOSES-CHEILITIS-KNUCKLE PADS SYNDROME Is also known as plack syndrome
Most common symptoms of PEELING SKIN-LEUKONYCHIA-ACRAL PUNCTATE KERATOSES-CHEILITIS-KNUCKLE PADS SYNDROME
- Hyperkeratosis
- Erythema
- Scarring
- Papule
- Palmoplantar keratoderma
More info about PEELING SKIN-LEUKONYCHIA-ACRAL PUNCTATE KERATOSES-CHEILITIS-KNUCKLE PADS SYNDROME
Search interest in CAST
Potential gene panels for CAST gene
CAST Panel
By Institute for Human Genetics University Clinic Freiburg
This panel specifically test the CAST gene.
More info about this panelPeeling skin syndrome NGS panel Panel
By Connective Tissue Gene Tests Peeling skin syndrome NGS panel that also includes the following genes: TGM5 CAST CHST8 CDSN CSTA FLG2 SERPINB8
More info about this panelPeeling skin syndrome Comprehensive panel Panel
By Connective Tissue Gene Tests Peeling skin syndrome Comprehensive panel that also includes the following genes: TGM5 CAST CHST8 CDSN CSTA FLG2 SERPINB8
More info about this panelPeeling skin syndrome Deletion / Duplication panel Panel
By Connective Tissue Gene Tests Peeling skin syndrome Deletion / Duplication panel that also includes the following genes: TGM5 CAST CHST8 CDSN CSTA FLG2 SERPINB8
More info about this panelCAST Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the CAST gene.
More info about this panelIf you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like HLX-AS1 MCEE BMS1 KANK2 CHSY1 MAGED2 IYD