BCL2 gene related symptoms and diseases
All the information presented here about the BCL2 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,NCBIGENE,HGNC, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to BCL2 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Insulin resistance | Uncommon - Between 30% and 50% cases |
| Neoplasm | Uncommon - Between 30% and 50% cases |
| Glucose intolerance | Uncommon - Between 30% and 50% cases |
| Lymphadenopathy | Rare - less than 30% cases |
| Enlarged ovaries | Rare - less than 30% cases |
Other less frequent symptoms and clinical features
Patients with BCL2 gene alterations may also develop some of the following symptoms and phenotypes:Rarely - Less than 30% cases
- Beta-cell dysfunction
- Fever
- Fatigue
- Diarrhea
- Splenomegaly
- Weight loss
- Respiratory tract infection
- Leukemia
And 39 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to BCL2 gene
Here you will find a list of rare diseases related to the BCL2. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
POLYCYSTIC OVARY SYNDROME 1; PCOS1
Alternate names
POLYCYSTIC OVARY SYNDROME 1; PCOS1 Is also known as pco, pco1, hyperandrogenemia, stein-leventhal syndrome, pcos
Description
a health problem that can affect a woman's menstrual cycle, fertility, hormones, insulin production, heart, blood vessels, and appearance
Most common symptoms of POLYCYSTIC OVARY SYNDROME 1; PCOS1
- Neoplasm
- Abnormality of metabolism/homeostasis
- Obesity
- Diabetes mellitus
- Apnea
More info about POLYCYSTIC OVARY SYNDROME 1; PCOS1
FOLLICULAR LYMPHOMA
Alternate names
FOLLICULAR LYMPHOMA Is also known as oncogene b-cell leukemia 2
Description
Follicular lymphoma is a form of non-Hodgkin lymphoma (see this term) characterized by a proliferation of B cells whose nodular structure of follicular architecture is preserved.
Most common symptoms of FOLLICULAR LYMPHOMA
- Neoplasm
- Fever
- Fatigue
- Diarrhea
- Splenomegaly
More info about FOLLICULAR LYMPHOMA
HIGH GRADE B-CELL LYMPHOMA WITH MYC AND/ OR BCL2 AND/OR BCL6 REARRANGEMENT
INTRAVASCULAR LARGE B-CELL LYMPHOMA
Alternate names
INTRAVASCULAR LARGE B-CELL LYMPHOMA Is also known as tappeiner-pfleger disease, angioendotheliomatosis proliferans systemisata, malignant angioendotheliomatosis, angiotropic large cell lymphoma, intravascular lymphomatosis
Description
Intravascular large B-cell lymphoma (IVLBCL) is a very rare form of diffuse large B-cell lymphoma (see this term) characterized by the selective growth of lymphoma cells within the lumina of small blood vessels (especially the capillaries) that most often presents with a wide range of clinical manifestations (as potentially any tissue can be involved), with patients from Western countries more frequently manifesting with neurological and cutaneous symptoms while patients from Asian countries more frequently displaying hepatosplenomegaly and thrombocytopenia. IVLBCL is characterized by an absence of lymphadenopathy, an aggressive clinical course and a poor prognosis.
More info about INTRAVASCULAR LARGE B-CELL LYMPHOMA
SOURCES: ORPHANET
Search interest in BCL2
If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like MEOX1 PRSS2 BRCA2 MT-RNR1 EGFR EBP IARS2