APOC3 gene related symptoms and diseases
All the information presented here about the APOC3 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,HGNC,OMIM,ORPHANET, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to APOC3 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Increased HDL cholesterol concentration | Very Common - Between 80% and 100% cases |
| Hypotriglyceridemia | Very Common - Between 80% and 100% cases |
| Decreased LDL cholesterol concentration | Uncommon - Between 30% and 50% cases |
| Hyperlipidemia | Uncommon - Between 30% and 50% cases |
| Hypercholesterolemia | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with APOC3 gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Precocious atherosclerosis
- Hyperlipoproteinemia
- Tendon xanthomatosis
Rare diseases associated to APOC3 gene
Here you will find a list of rare diseases related to the APOC3. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
APOLIPOPROTEIN C-III DEFICIENCY
Alternate names
APOLIPOPROTEIN C-III DEFICIENCY Is also known as hyperalphalipoproteinemia 2, halp2
Most common symptoms of APOLIPOPROTEIN C-III DEFICIENCY
- Decreased LDL cholesterol concentration
- Increased HDL cholesterol concentration
- Hypotriglyceridemia
More info about APOLIPOPROTEIN C-III DEFICIENCY
CHOLESTEROL-ESTER TRANSFER PROTEIN DEFICIENCY
Alternate names
CHOLESTEROL-ESTER TRANSFER PROTEIN DEFICIENCY Is also known as cept deficiency, familial hyperalphalipoproteinemia
Most common symptoms of CHOLESTEROL-ESTER TRANSFER PROTEIN DEFICIENCY
- Hyperlipidemia
- Hypercholesterolemia
- Precocious atherosclerosis
- Hyperlipoproteinemia
- Tendon xanthomatosis
More info about CHOLESTEROL-ESTER TRANSFER PROTEIN DEFICIENCY
SOURCES: ORPHANET
Search interest in APOC3
Potential gene panels for APOC3 gene
APOC3 Panel
Germany.
By Institute for Human Genetics University Clinic Freiburg
This panel specifically test the APOC3 gene.
More info about this panel Germany.
Dyslipidemia NGS panel (29 genes), Sequence & CNV analysis Panel
Netherlands.
By Laboratory of genome diagnostics Academic Medical Center, University of Amsterdam Dyslipidemia NGS panel (29 genes), Sequence & CNV analysis that also includes the following genes: SAR1B SLCO1B1 ABCG5 ABCG8 LMF1 SCARB1 APOA5 LDLRAP1 CETP PCSK9
More info about this panel Netherlands.
APOC3. Complete sequencing Panel
Spain.
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the APOC3 gene.
More info about this panel Spain.
Hyperalphalipoproteinemia 2 Panel
Germany.
By Laboratory for Molecular Diagnostics Center for Nephrology and Metabolic Disorders
This panel specifically test the APOC3 gene.
More info about this panel Germany.
Inherited Cardiovascular Diseases and Sudden Death Panel Panel
Spain.
By Health in Code Inherited Cardiovascular Diseases and Sudden Death Panel that also includes the following genes: MRPL3 RYR2 SCN10A SCN1B SCN2B SCN4B SCN5A BMPR1B BMPR2 SGCA
More info about this panel Spain.
Cardiovascular Diseases_General Panel Panel
Spain.
By Health in Code Cardiovascular Diseases_General Panel that also includes the following genes: RIT1 MRPL3 RRAS RYR1 RYR2 SAR1B BLK SCN10A SCN1B SCN2B
More info about this panel Spain.
Dyslipidemias / Early atherosclerosis Panel
Spain.
By Health in Code Dyslipidemias / Early atherosclerosis that also includes the following genes: RYR1 SAR1B BLK SLCO1B1 SLC22A8 SLC2A2 HNF1A HNF1B KLF11 WFS1
More info about this panel Spain.
Primary familial hypertriglyceridemias Panel
Spain.
By Health in Code Primary familial hypertriglyceridemias that also includes the following genes: LMF1 PCDH15 TRIB1 APOA5 GPIHBP1 SLC25A40 PNPLA2 GPD1 APOC2 APOC3
More info about this panel Spain.
Hypolipidemias Panel
Spain.
By Health in Code Hypolipidemias that also includes the following genes: SAR1B PCSK9 MYLIP ANGPTL3 APOC3 LCAT ABCG1 MTTP
More info about this panel Spain.
Early-Onset Coronary Artery Disease/Familial Hypercholesterolemia Full Gene Sequencing Panel Panel
United States.
By Integrated Genetics Westborough Integrated Genetics Early-Onset Coronary Artery Disease/Familial Hypercholesterolemia Full Gene Sequencing Panel that also includes the following genes: PCSK9 APOC3 LDLR PON2
More info about this panel United States.
APOC3 Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the APOC3 gene.
More info about this panel United States.
Hyperlipidemia Panel Panel
Finland.
By Blueprint Genetics Hyperlipidemia Panel that also includes the following genes: ABCG5 ABCG8 LMF1 APOA5 LDLRAP1 CREB3L3 PCSK9 GPIHBP1 ALMS1 APOC2
More info about this panel Finland.
Hyperalphalipoproteinemia 2 Panel
Spain.
By Bioarray
This panel specifically test the APOC3 gene.
More info about this panel Spain.
Hyperalphalipoproteinemia Type 2 , Sequencing APOC3 Gene Panel
Spain.
By Reference Laboratory Genetics
This panel specifically test the APOC3 gene.
More info about this panel Spain.
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