APOA5 gene related symptoms and diseases
All the information presented here about the APOA5 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,OMIM,HGNC,ORPHANET, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to APOA5 gene
Symptoms // Phenotype | % Cases |
---|---|
Diabetes mellitus | Very Common - Between 80% and 100% cases |
Decreased HDL cholesterol concentration | Very Common - Between 80% and 100% cases |
Increased VLDL cholesterol concentration | Very Common - Between 80% and 100% cases |
Atheroeruptive xanthoma | Uncommon - Between 30% and 50% cases |
Abnormal glucose tolerance | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with APOA5 gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Acute pancreatitis
- Hyperlipoproteinemia
- Precocious atherosclerosis
- Hypopituitarism
- Pancreatitis
- Shock
- Hyperlipidemia
- Hypocalcemia
And 5 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to APOA5 gene
Here you will find a list of rare diseases related to the APOA5. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
HYPERLIPOPROTEINEMIA TYPE 5
Alternate names
HYPERLIPOPROTEINEMIA TYPE 5 Is also known as major hyperlipidemia, hyperlipemia, combined fat and carbohydrate-induced, hyperlipidemia, type v, hyperchylomicronemia, late-onset, hyperlipemia, mixed, hlp type 5, hyperchylomicronemia with hyperprebetalipoproteinemia, familial
Description
A severe type of hyperlipidemia, sometimes familial, that is characterized by the elevation of both plasma CHYLOMICRONS and TRIGLYCERIDES contained in VERY-LOW-DENSITY LIPOPROTEINS. Type V hyperlipoproteinemia is often associated with DIABETES MELLITUS and is not caused by reduced LIPOPROTEIN LIPASE activity as in HYPERLIPOPROTEINEMIA TYPE I .
Most common symptoms of HYPERLIPOPROTEINEMIA TYPE 5
- Diabetes mellitus
- Decreased HDL cholesterol concentration
- Decreased LDL cholesterol concentration
- Increased VLDL cholesterol concentration
- Increased circulating chylomicron concentration
More info about HYPERLIPOPROTEINEMIA TYPE 5
HYPERTRIGLYCERIDEMIA, FAMILIAL
Description
Most individuals with familial hypertriglyceridemia have a hyperlipoproteinemia IV (OMIM ) phenotype. Relatives of affected persons (ascertained in a study of survivors of coronary occlusion) were found to have normal cholesterol distribution and bimodal triglyceride distribution (Goldstein et al., 1973). Hypertriglyceridemia is not completely expressed in affected children.
Most common symptoms of HYPERTRIGLYCERIDEMIA, FAMILIAL
- Diabetes mellitus
- Abnormality of the cardiovascular system
- Hypertriglyceridemia
- Hypocalcemia
- Hyperlipidemia
More info about HYPERTRIGLYCERIDEMIA, FAMILIAL
SOURCES: OMIM
Search interest in APOA5
Potential gene panels for APOA5 gene
Hypertriglyceridemias Panel Panel
By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University Hypertriglyceridemias Panel that also includes the following genes: LMF1 APOA5 GPIHBP1 APOC2
More info about this panelAPOA5 Panel
By Institute for Human Genetics University Clinic Freiburg
This panel specifically test the APOA5 gene.
More info about this panelDyslipidemia NGS panel (29 genes), Sequence & CNV analysis Panel
By Laboratory of genome diagnostics Academic Medical Center, University of Amsterdam Dyslipidemia NGS panel (29 genes), Sequence & CNV analysis that also includes the following genes: SAR1B SLCO1B1 ABCG5 ABCG8 LMF1 SCARB1 APOA5 LDLRAP1 CETP PCSK9
More info about this panelAPOA5. Complete sequencing Panel
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the APOA5 gene.
More info about this panelHyperlipoproteinemia type 4 (sequence analysis of APOA5 gene) Panel
By CGC Genetics
This panel specifically test the APOA5 gene.
More info about this panelObesity genetic testing Panel
By CGC Genetics Obesity genetic testing that also includes the following genes: APOA5 INSIG2 FTO GNB3 MC4R
More info about this panelHYPERLIPOPROTEINEMIA, TYPE V Panel
By Laboratory for Molecular Diagnostics Center for Nephrology and Metabolic Disorders
This panel specifically test the APOA5 gene.
More info about this panelHypertriglyceridemia Panel
By Laboratory for Molecular Diagnostics Center for Nephrology and Metabolic Disorders
This panel specifically test the APOA5 gene.
More info about this panelChylomicronemia Panel
By Laboratory for Molecular Diagnostics Center for Nephrology and Metabolic Disorders Chylomicronemia that also includes the following genes: APOA5 GPIHBP1 APOC2 APOE
More info about this panelType 3 hyperlipoproteinemia Panel
By Unit for Cardiac and Cardiavasular Genetics Oslo University Hospital HF - Ullevaal Type 3 hyperlipoproteinemia that also includes the following genes: LMF1 APOA5 GPIHBP1 APOC2
More info about this panelComprehensive Cardiology Sequencing Panel with CNV Detection Panel
By PreventionGenetics PreventionGenetics Comprehensive Cardiology Sequencing Panel with CNV Detection that also includes the following genes: RYR1 RYR2 SCN1B SCN2B SCN4B SCN5A SCO2 SGCD SGCG BRAF
More info about this panelSingle gene testing APOA5 Panel
By CeGaT GmbH
This panel specifically test the APOA5 gene.
More info about this panelHyperlipoproteinemia, type 5 Panel
By Asper Biogene Asper Biogene LLC
This panel specifically test the APOA5 gene.
More info about this panelHypertriglyceridemia Panel
By Asper Biogene Asper Biogene LLC Hypertriglyceridemia that also includes the following genes: LMF1 APOA5 GPIHBP1 GPD1 APOC2
More info about this panelInherited Cardiovascular Diseases and Sudden Death Panel Panel
By Health in Code Inherited Cardiovascular Diseases and Sudden Death Panel that also includes the following genes: MRPL3 RYR2 SCN10A SCN1B SCN2B SCN4B SCN5A BMPR1B BMPR2 SGCA
More info about this panelCardiovascular Diseases_General Panel Panel
By Health in Code Cardiovascular Diseases_General Panel that also includes the following genes: RIT1 MRPL3 RRAS RYR1 RYR2 SAR1B BLK SCN10A SCN1B SCN2B
More info about this panelDyslipidemias / Early atherosclerosis Panel
By Health in Code Dyslipidemias / Early atherosclerosis that also includes the following genes: RYR1 SAR1B BLK SLCO1B1 SLC22A8 SLC2A2 HNF1A HNF1B KLF11 WFS1
More info about this panelPrimary familial hypertriglyceridemias Panel
By Health in Code Primary familial hypertriglyceridemias that also includes the following genes: LMF1 PCDH15 TRIB1 APOA5 GPIHBP1 SLC25A40 PNPLA2 GPD1 APOC2 APOC3
More info about this panelHypertriglyceridaemia genetic screen Panel
By Cardiovascular Genetics Laboratory PathWest Laboratory Medicine WA Hypertriglyceridaemia genetic screen that also includes the following genes: LMF1 APOA5 GPIHBP1 APOC2 APOE
More info about this panelMajor Hypertriglyceridemia: sequencing of APOA5 gene Panel
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases
This panel specifically test the APOA5 gene.
More info about this panelMAJOR HYPERTRIGLYCERIDEMIA Panel
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases MAJOR HYPERTRIGLYCERIDEMIA that also includes the following genes: LMF1 APOA5 LIPI CREB3L3 GPIHBP1 APOC2
More info about this panelAPOA5 Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the APOA5 gene.
More info about this panelPancreatitis Panel Panel
By Blueprint Genetics Pancreatitis Panel that also includes the following genes: SPINK1 UBR1 APOA5 CFTR CPA1 GPIHBP1 CTRC APOC2 PRSS1
More info about this panelHyperlipidemia Panel Panel
By Blueprint Genetics Hyperlipidemia Panel that also includes the following genes: ABCG5 ABCG8 LMF1 APOA5 LDLRAP1 CREB3L3 PCSK9 GPIHBP1 ALMS1 APOC2
More info about this panelFamilial hypertriglyceridemia Panel
By Bioarray
This panel specifically test the APOA5 gene.
More info about this panelHypertriglyceridemia Panel
By Molecular Diagnostic Laboratory for Inherited Cardiovascular Disease Montreal Heart Institute Hypertriglyceridemia that also includes the following genes: LMF1 APOA5 GPIHBP1 APOC2
More info about this panelHYPERLIPOPROTEINEMIA TYPE 5 Panel
By Laboratorio de Genetica Clinica SL
This panel specifically test the APOA5 gene.
More info about this panelMAJOR HYPERTRIGLYCERIDEMIA Panel
By Laboratorio de Genetica Clinica SL MAJOR HYPERTRIGLYCERIDEMIA that also includes the following genes: LMF1 APOA5 LIPI GPIHBP1 APOC2
More info about this panelMAJOR HYPERTRIGLYCERIDEMIA SANGER PANEL Panel
By Laboratorio de Genetica Clinica SL MAJOR HYPERTRIGLYCERIDEMIA SANGER PANEL that also includes the following genes: LMF1 APOA5 LIPI GPIHBP1 APOC2
More info about this panelMajor Hypertriglyceridemia, Sequencing APOA5 Gene Panel
By Reference Laboratory Genetics
This panel specifically test the APOA5 gene.
More info about this panelMajor Hypertriglyceridemia, Panel Massive Sequencing (NGS) 7 Genes Panel
By Reference Laboratory Genetics Major Hypertriglyceridemia, Panel Massive Sequencing (NGS) 7 Genes that also includes the following genes: LMF1 APOA5 LIPI GPIHBP1 APOC2 APOE
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