ANO10 gene related symptoms and diseases
All the information presented here about the ANO10 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,HGNC,ORPHANET,NCBIGENE, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to ANO10 gene
Symptoms // Phenotype | % Cases |
---|---|
Intellectual disability | Very Common - Between 80% and 100% cases |
Ankle clonus | Very Common - Between 80% and 100% cases |
Fasciculations | Very Common - Between 80% and 100% cases |
Truncal ataxia | Very Common - Between 80% and 100% cases |
Horizontal nystagmus | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with ANO10 gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- EMG abnormality
- Macular degeneration
- Slurred speech
- Brisk reflexes
- Progressive gait ataxia
- Limb ataxia
- Slow saccadic eye movements
- Saccadic smooth pursuit
And 27 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to ANO10 gene
Here you will find a list of rare diseases related to the ANO10. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
ADULT-ONSET AUTOSOMAL RECESSIVE CEREBELLAR ATAXIA
Alternate names
ADULT-ONSET AUTOSOMAL RECESSIVE CEREBELLAR ATAXIA Is also known as scar10, autosomal recessive spinocerebellar ataxia type 10
Description
Autosomal recessive spinocerebellar ataxia-10 is an autosomal recessive neurodegenerative disorder with onset in the teenage or young adult years of gait and limb ataxia, dysarthria, and nystagmus associated with marked cerebellar atrophy on brain imaging (summary by Vermeer et al., 2010). Some patients have low levels of coenzyme Q10 (CoQ10) in muscle and may show some clinical improvement with CoQ10 treatment (Balreira et al., 2014).
Most common symptoms of ADULT-ONSET AUTOSOMAL RECESSIVE CEREBELLAR ATAXIA
- Intellectual disability
- Seizures
- Ataxia
- Nystagmus
- Cataract
More info about ADULT-ONSET AUTOSOMAL RECESSIVE CEREBELLAR ATAXIA
Search interest in ANO10
Potential gene panels for ANO10 gene
Ataxia, Supplemental Recessive Evaluation Panel
By Athena Diagnostics Inc Ataxia, Supplemental Recessive Evaluation that also includes the following genes: SACS TTPA APTX COQ8A SYNE1 TDP1 SYT14 SIL1 FLVCR1 ANO10
More info about this panelAtaxia, Complete Recessive Evaluation Panel
By Athena Diagnostics Inc Ataxia, Complete Recessive Evaluation that also includes the following genes: SACS TTPA APTX COQ8A SYNE1 TDP1 SYT14 SIL1 FLVCR1 ANO10
More info about this panelAtaxia, Comprehensive Evaluation Panel
By Athena Diagnostics Inc Ataxia, Comprehensive Evaluation that also includes the following genes: SACS ATXN1 ATXN10 ATXN2 ATXN7 ATXN8OS SLC1A3 SPTBN2 TBP TTPA
More info about this panelAtaxia Exome Panel Panel
By Genetic Services Laboratory University of Chicago Ataxia Exome Panel that also includes the following genes: BCS1L RTN2 SACS SCN1A SCN2A SCN8A SCO1 SDHA SDHD SLC16A2
More info about this panelSpinocerebellar ataxia 10, AR (SCAR10, sequence analysis of ANO10 gene) Panel
By CGC Genetics
This panel specifically test the ANO10 gene.
More info about this panelHereditary ataxias (NGS panel for 44 genes) Panel
By CGC Genetics Hereditary ataxias (NGS panel for 44 genes) that also includes the following genes: SACS SLC1A3 SPTBN2 TTPA VAMP1 VLDLR CACNA1A CACNB4 ELOVL4 ABHD12
More info about this panelAutosomal Recessive Spinocerebellar Ataxia-10 via ANO10 Gene Sequencing with CNV Detection Panel
By PreventionGenetics PreventionGenetics
This panel specifically test the ANO10 gene.
More info about this panelMental retardation - different panels Panel
By Institute of Human Genetics Uniklinik RWTH Aachen Mental retardation - different panels that also includes the following genes: RGS7 RIT1 RMRP BCS1L RPL10 RPS6KA3 RRAS SALL1 SC5D ATXN10
More info about this panelCoQ10 Deficiency Panel
By MGZ Medical Genetics Center CoQ10 Deficiency that also includes the following genes: APTX COQ8A PDSS1 COQ6 PDSS2 COQ2 COQ9 ANO10 ETFA ETFB
More info about this panelANO10 Panel
By MGZ Medical Genetics Center
This panel specifically test the ANO10 gene.
More info about this panelNeurogenetic Disorders - panels Panel
By MGZ Medical Genetics Center Neurogenetic Disorders - panels that also includes the following genes: BCS1L RTN2 RYR1 SACS SCN1A SCN1B SCN2A SCN8A SCO1 SCO2
More info about this panelMitochondrial Diseases Panel
By MGZ Medical Genetics Center Mitochondrial Diseases that also includes the following genes: BCS1L SCO1 SCO2 SDHA SDHB SDHC SDHD SLC19A2 SLC22A5 SLC25A12
More info about this panelAllNeuro panel Panel
By Centogene AG - the Rare Disease Company AllNeuro panel that also includes the following genes: BCS1L ROR2 RPL10 BDNF RPS6KA3 RTN2 RYR1 SACS BIN1 SBF1
More info about this panelSpinocerebellar ataxia type 10, autosomal recessive Panel
By Centogene AG - the Rare Disease Company
This panel specifically test the ANO10 gene.
More info about this panelAtaxia and differential diagnoses Panel Panel
By CeGaT GmbH Ataxia and differential diagnoses Panel that also includes the following genes: RPIA SACS ATXN1 ATXN10 ATXN2 ATXN7 SCN2A SLC17A5 SLC1A3 SLC6A1
More info about this panelSingle gene testing ANO10 Panel
By CeGaT GmbH
This panel specifically test the ANO10 gene.
More info about this panelAtaxia, autosomal recessive and X-linked Panel Panel
By CeGaT GmbH Ataxia, autosomal recessive and X-linked Panel that also includes the following genes: SACS SLC9A1 SPG7 SPTBN2 STUB1 TTPA WWOX ATP8A2 CA8 SNX14
More info about this panelSpinocerebellar Ataxia Panel
By Asper Biogene Asper Biogene LLC Spinocerebellar Ataxia that also includes the following genes: SACS SLC9A1 SLC9A6 SPTBN2 STUB1 TWNK ACO2 TTPA WFS1 WWOX
More info about this panelAtaxia Panel
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases Ataxia that also includes the following genes: SACS SLC1A3 SPTBN2 TTPA CACNA1A CACNB4 APTX TGM6 COQ8A SYNE1
More info about this panelANO10 Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the ANO10 gene.
More info about this panelAtaxia Panel Panel
By Blueprint Genetics Ataxia Panel that also includes the following genes: SACS SLC1A3 SLC20A2 SLC2A1 SLC9A6 SPG7 SPTBN2 STUB1 TWNK ACO2
More info about this panelComprehensive Metabolism Panel Panel
By Blueprint Genetics Comprehensive Metabolism Panel that also includes the following genes: BCS1L CNNM2 RYR1 CNNM4 SCN4A SEC23B SGSH SI SLC40A1 SLC12A3
More info about this panelCoenzyme q10 Deficiency Panel Panel
By Blueprint Genetics Coenzyme q10 Deficiency Panel that also includes the following genes: APTX COQ8A PDSS1 COQ4 COQ6 SLC25A26 COQ7 PDSS2 COQ2 COQ9
More info about this panelSPINOCEREBELLAR ATAXIA NGS PANEL Panel
By Laboratorio de Genetica Clinica SL SPINOCEREBELLAR ATAXIA NGS PANEL that also includes the following genes: SPTBN2 STUB1 TWNK TTPA WWOX CA8 CACNA1A CACNA1G ELOVL4 APTX
More info about this panelCoenzyme Q10 Deficiency , Panel Massive Sequencing (NGS) 12 Genes Panel
By Reference Laboratory Genetics Coenzyme Q10 Deficiency , Panel Massive Sequencing (NGS) 12 Genes that also includes the following genes: APTX COQ8A PDSS1 COQ4 COQ6 PDSS2 COQ2 COQ9 ANO10 ETFA
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